American Journal of Biomedical and Life Sciences

Volume 7, Issue 1, February 2019

  • In Vitro Study on the Antimicrobial Activity of Curcuma Longa Rhizome on Some Microorganism

    Mbah-Omeje, Kelechi Nkechinyere

    Issue: Volume 7, Issue 1, February 2019
    Pages: 1-5
    Received: 23 November 2018
    Accepted: 20 December 2018
    Published: 15 February 2019
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    Abstract: The present study investigates the antimicrobial activity, phytochemical and minimum inhibitory concentration (MIC) of Curcuma longa rhizome extract on Staphylococcus aureus, Staphylococcus epidermidis and Streptococcus salivarius. Methanol, and chloroform extracts of the plant rhizome were collected and obtained by standard methods. All the solven... Show More
  • Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle

    Janet Ogochukwu Nzoputam, Ezeuchu Favour Udochukwu, Emmanuel Amabebe

    Issue: Volume 7, Issue 1, February 2019
    Pages: 6-9
    Received: 28 December 2018
    Accepted: 23 January 2019
    Published: 15 February 2019
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    Abstract: Introduction: Electrolyte-dependent water retention associated with hormonal changes during the menstrual cycle may alter the normal reference intervals of plasma electrolytes with important effects on central nervous system, cardiovascular and renal functions. Hence, we sought to determine and compare plasma electrolytes (sodium, potassium, bicarb... Show More
  • Investigation of Antibacterial Activity of Crude Extracts from Marine Snails and Bivalves in the Southern Coast of Vietnam

    Pham Xuan Ky, Pham Thi Mien, Le Ho Khanh Hy, Dao Viet Ha, Nguyen Phuong Anh, Doan Thi Thiet, Phan Bao Vy, Ho Van The

    Issue: Volume 7, Issue 1, February 2019
    Pages: 10-15
    Received: 12 February 2019
    Accepted: 14 March 2019
    Published: 10 April 2019
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    Abstract: The primary antibacterial activity of methanol and chloroform crude extracts from marine snails and bivalves was assessed by using the agar diffusion technique against four bacterial strains. Active methanol extracts were then characterized using TLC, SDS-PAGE and FTIR. Methanol extracts from 5 snail species and 8 extracts from 12 bivalve species p... Show More
  • Mansonella perstans and Plasmodium falciparum Co-infection in the Akonolinga Health District, Centre Region, Cameroon

    Leopold Gustave Lehman, Martin Gael Oyono, Samuel Fosso, Charles Félix Bilong Bilong

    Issue: Volume 7, Issue 1, February 2019
    Pages: 16-21
    Received: 25 February 2019
    Accepted: 28 March 2019
    Published: 13 April 2019
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    Abstract: Mansonella perstans and Plasmodium falciparum are among the most common human parasites in Sub-Saharan Africa. They pass through the bloodstream during their life in human host. This study aimed at determining the prevalence, determinants of co-infection with M. perstans and P. falciparum and their possible interaction mechanism. A cross-sectional ... Show More
  • Rational Design and Construction of a Knock-Out Vector for Targeting the Decoy Type 2 Interleukin -1 Receptor

    Faith Owabhel Robert, Emmanuel Amabebe

    Issue: Volume 7, Issue 1, February 2019
    Pages: 22-30
    Received: 6 January 2019
    Accepted: 2 April 2019
    Published: 22 April 2019
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    Abstract: Given the limited data describing the phenotype for type 2 interleukin -1 receptor (Il1r2-/-) in mouse strains and based on the decoy role of the gene product (IL-1R2), we hypothesized that IL-1R2 may have a unique but similar inhibitory role to IL-1R antagonist (IL-1Ra) in vivo. Despite the anti-inflammatory function of IL-1R2, its role in disease... Show More