American Journal of Clinical and Experimental Medicine

Volume 4, Issue 6, November 2016

  • The Protection Effect of Topical Cocoa Extract on Cyclobutane Pyrimidine Dimer (CPD) Formation and Tissue Neutrophil in Mice Induced by Ultraviolet B

    Utin Variantini, Safruddin Amin, Anni Adriani, Idham Jaya Ganda, Gemini Alam, M. Husni Cangara

    Issue: Volume 4, Issue 6, November 2016
    Pages: 160-165
    Received: 18 September 2016
    Accepted: 27 September 2016
    Published: 19 October 2016
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    Abstract: Ultraviolet (UV) radiation has dangerous effects on the skin that may cause multiple clinical and cellular effects, which will produce DNA damage characterized by formation of photoproducts such as cyclobutane pyrimidine dimer (CPD), and acute inflammation characterized by neutrophil infiltration in the skin tissues. Cocoa flavanols are natural ant... Show More
  • Pattern of Esophageal Cancer in Sudan

    Ali Adam Elhadi, Hyder Osman Mirghani, Yassin Ibrahim, Ibrahim Abdullah Albalawi

    Issue: Volume 4, Issue 6, November 2016
    Pages: 166-169
    Received: 26 September 2016
    Accepted: 5 October 2016
    Published: 27 October 2016
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    Abstract: Objectives: Carcinoma of the esophagus is the eights common cancer worldwide causing a lot of morbidity and mortality, defining the risk factors could aid prevention. In the current study, we aimed to explore the pattern of esophageal cancer in Sudan. Methods: Seventy-two patients referred for upper gastrointestinal endoscopy and diagnosed with eso... Show More
  • Effectivity of Preovulation Phase Autologous Serum Application on Moderate-Severe Acne Vulgaris Patients

    Nurhayati Edison, Safruddin Amin, Khairuddin Djawad, Raden Satriono, Yohanes Widodo, Marianti A. Manggau

    Issue: Volume 4, Issue 6, November 2016
    Pages: 170-178
    Received: 16 September 2016
    Accepted: 28 September 2016
    Published: 10 November 2016
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    Abstract: Acne vulgaris (AV) is the most common skin disease, including in Indonesia. This research aims to determine the effectivity of preovulation phase autologous serum application in patients with moderate-severe AV. This research was conducted in Makassar, South Sulawesi. Thirteen patient samples with moderate-severe AV who have met the inclusion crite... Show More
  • Evaluation of Anti-ulcerogenic Activity in Oil Extract of Jintan Hitam (Nigella sativa) Against Ethanol Induced Gastric Ulcer in Mice (Mus musculus)

    Syamsu Rijal, Upik Anderiani Miskad, Djumadi Achmad, Rina Masadah, Dasril Daud, Cahyono Kaelan, Halida Rahawarin, Swandari Paramita, Yadi Yasir

    Issue: Volume 4, Issue 6, November 2016
    Pages: 179-184
    Received: 3 October 2016
    Accepted: 22 October 2016
    Published: 14 November 2016
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    Abstract: Jintan hitam (Nigella sativa) has been widely used in traditional medicine to treat several diseases, including gastric ulcer. However, there are no scientific data demonstrating anti-ulcerogenic activity conferred by use of jintan hitam. The present study aimed to evaluate the antiulcer properties of oil extract from jintan hitam. In the gastric u... Show More
  • Impact of Juvenile Idiopathic Arthritis on School Attendance and Performance

    Kamrul Laila, Mujammel Haque, Md. Mahbubul Islam, Mohammad Imnul Islam, Manik Kumar Talukder, Shahana Akhter Rahman

    Issue: Volume 4, Issue 6, November 2016
    Pages: 185-190
    Received: 23 September 2016
    Accepted: 21 October 2016
    Published: 14 November 2016
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    Abstract: Juvenile idiopathic arthritis (JIA) includes a group of disorders characterized by chronic arthritis. It is the most common chronic rheumatic illness in children and is a significant cause of morbidity, disability and dysfunction. Therefore, the potential for school attendance and academic performance become compromised and these children are often... Show More
  • Effects of Preventive Long-Term Treatment with Strontium Ranelate and Zoledronic Acid on Bone Quality in Ovariectomized Rats

    Marta Martín-Fernández, Marina Gómez-Chinchón, Luis Álvarez, Blanca Torrubia, Manuel Díaz-Curiel, David Guede, Jose Ramón Caeiro, Cristobalina Rodríguez-Álvarez, Concepción de la Piedra

    Issue: Volume 4, Issue 6, November 2016
    Pages: 191-200
    Received: 3 September 2016
    Accepted: 18 September 2016
    Published: 15 November 2016
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    Abstract: The aim of this work was to study the effects on bone quality produced by long-range treatment with zoledronic acid (ZA) or strontium ranelate (SrR) in ovariectomized rats. Sixty 6-month-old female Wistar rats were divided: SHAM (n=15), simulated intervention; OVX (n=15), ovariectomized; OVX+ZA (n=15), ovariectomized treated with ZA (0.083 mg/kg i.... Show More
  • Many Infectious Human Diseases Can be Arrested with Oxygen

    Delik D. Gabaev

    Issue: Volume 4, Issue 6, November 2016
    Pages: 201-203
    Received: 29 July 2016
    Accepted: 29 October 2016
    Published: 23 November 2016
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    Abstract: Many bacteria and viruses that cause dangerous diseases for all living things, appeared on Earth when there was no oxygen on the planet. Therefore, they are anaerobe organisms. Atmospheric oxygen is baleful for them. In case of a disease, the oxygen delivery arrest the infection and cancer cells.
  • Inhalation of Bacterial Cellulose Nanofibers Facilitates Silica Particle Clearance in a Rat Silicosis Model

    Wen-Chuan Li, Nai-Fang Fu, Jun-Cai Wu, Xian-Jun Li, Rui-Hui Pan, Yan-Yan Zheng, Yong-Jin Gan, Jian-An Ling, Heng-Qiu Liang, Dan-Yu Liang, Jing Xie, Zhi-Chao Dong, Sheng-Jun Jiang

    Issue: Volume 4, Issue 6, November 2016
    Pages: 204-211
    Received: 22 November 2016
    Published: 24 November 2016
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    Abstract: Background: Millions of workers globally are afflicted by pneumoconiosis, a disease caused by inhaling dust or particles. A particularly prevalent form is silicosis, caused by inhaling silica particles. The Chinese herbal medicine kombucha, which contains Gluconacetobacter xylinus and yeasts, can effectively clear dust from rats’ lungs. The study p... Show More
  • Severe Impaired Bone Formation was Induced by Short-Term Fasting in Adult Mice

    Jiajing Chen, Rui He, Juan Li, Yan Zhang, Jinwei Qi, Xianghui Meng, Yuying Wang

    Issue: Volume 4, Issue 6, November 2016
    Pages: 212-215
    Received: 6 December 2016
    Published: 7 December 2016
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    Abstract: The alterations in bone metabolism were associated with food and nutrition. Regrettably is that no studies have analyzed the bone microstructure subjected to complete fasting in mammals. Our study aimed to identify the effects and alterations of complete fasting on bones via histomorphometric analysis in adult female mice. Twelve-week-old C57BL/6J ... Show More
  • Assessment of Cardiovascular Disease Risk in Type 2 Diabetic Patients: A Comparison of Risk Indices

    Brown Holy, Obi Doris Chidinma

    Issue: Volume 4, Issue 6, November 2016
    Pages: 216-220
    Received: 30 October 2016
    Accepted: 19 November 2016
    Published: 26 December 2016
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    Abstract: Diabetes mellitus is a major public health problem; it is synchronized with the development of many complications of which cardiovascular disease is the most prevalent and detrimental. This study aimed at comparing the strength of various cardiovascular risk indices among diabetes type 2 patients. The risk indices evaluated were: Apoprotein A1, Apo... Show More