American Journal of Clinical and Experimental Medicine

Volume 3, Issue 3, May 2015

  • The Risk Factors of Early Onset Neonatal Sepsis

    Muhammad Hayun, Ema Alasiry, Dasril Daud, Dwi Bahagia Febriani, Djauhariah Madjid

    Issue: Volume 3, Issue 3, May 2015
    Pages: 78-82
    Received: 24 March 2015
    Accepted: 7 April 2015
    Published: 17 April 2015
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    Abstract: Introduction: Neonatal sepsis is one of the major causes of morbidity and mortality in newborn. Early onset neonatal sepsis (EONS) is a severe disease and has high mortality rate. The clinical signs of EONS are nonspecific and the confirmation of diagnosis may consuming time. Therefore, the diagnostic approach is necessary by considering the risk f... Show More
  • Multiple Sclerosis: Effect of Oral Administration of an Antioxidant Dietary Supplement in C57BL6/N Induced Model of Experimental Autoimmune Encephalomyelitis

    Torricelli Piera, Antonelli Francesco, Ferorelli Pasquale, De Martino Angelo, Shevchenko Anna, Beninati Simone

    Issue: Volume 3, Issue 3, May 2015
    Pages: 83-87
    Received: 26 March 2015
    Accepted: 9 April 2015
    Published: 18 April 2015
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    Abstract: In the pathogenesis of demyelinating diseases including multiple sclerosis (MS) an important role is played by oxidative stress. Increased energy requirements during remyelination of axons and mitochondria failure is one of the causes of axonal degeneration and disability in MS. In the presence of neurological diseases such as MS, F2-isoprostanes a... Show More
  • Relationship Between Severity Levels of Diseases in Children with Maternal Anxiety at Pediatric Intensive Care Unit

    Imelda, Martira Maddeppungeng, Idham Jaya Ganda, Dasril Daud

    Issue: Volume 3, Issue 3, May 2015
    Pages: 94-98
    Received: 7 April 2015
    Accepted: 16 April 2015
    Published: 24 April 2015
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    Abstract: Background: PICU (pediatric intensive care unit) is child care units that require intensive surveillance and invasive action. A state of anxious disorder is characterized by feelings of fear which accompanied by somatic complaints shown with hyperactivities of autonomic nervous system and non-specific symptom and normal emotion. Objective: This stu... Show More
  • Profile of mRNA Expression of IL-6 and IL-10 in Breast Cancer Patients with or Without Chemotherapy

    Victor Pontoh, Daniel Sampepajung, Andi Asadul Islam, Mochammad Hatta

    Issue: Volume 3, Issue 3, May 2015
    Pages: 99-104
    Received: 31 March 2015
    Accepted: 25 April 2015
    Published: 11 May 2015
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    Abstract: ackground: Breast cancer is a type of cancer that has a high prevalence, can occur in men and women. Cytokines are factors that are known to have good properties of tumor growth and tumor inhibitory effects. Cytokine has an important role in the control of the immune system. Development of breast carcinoma is closely related to mRNA expression of I... Show More
  • Serum Lipocalin 2 Levels in Acute Exercised Prediabetic Rat Model in Comparison to Normal Healthy Control

    Rania Reafaat Abdelkader Atia, Khaled Abdelfattah Abdelhamid Abulfadle

    Issue: Volume 3, Issue 3, May 2015
    Pages: 105-109
    Received: 24 April 2015
    Accepted: 4 May 2015
    Published: 13 May 2015
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    Abstract: Background: Excess caloric intake expands adipose tissue resulting in a higher risk of metabolic disease. Lipocalin 2 (LCN2) is an adipokine having a role in innate immunity and energy metabolism. It is an acute phase protein that was recently correlated with potential effects on obesity and inflammation. The reaction of this protein to progressive... Show More
  • Study of the Validity of Neutrophil CD64 and Serum Procalcitonin as Diagnostic Markers to Discriminate Infection from Disease Activity in Patients with Systemic Lupus Erythematosus

    Ahmed Ragheb, Ahmed A. Sonbol

    Issue: Volume 3, Issue 3, May 2015
    Pages: 110-117
    Received: 21 April 2015
    Accepted: 27 April 2015
    Published: 13 May 2015
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    Abstract: Introduction: In addition to the complexity of the clinical presentation of both infections and disease activity in systemic lupus erythematosus (SLE) patients, the difficulty in making the therapeutic decision require investigations that should be of diagnostic value. Neutrophil CD64 is up regulated within few hours in patients with infection. Sim... Show More
  • Antimicrobial Activity of Lippia adoensis var. koseret Against Human Pathogenic Bacteria and Fungi

    Gemechu Ameya Buli, Abdella Gure Duga, Engda Dessalegn

    Issue: Volume 3, Issue 3, May 2015
    Pages: 118-123
    Received: 29 March 2015
    Accepted: 12 April 2015
    Published: 19 May 2015
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    Abstract: Background: Lippia adoensis var. koseret is a well known medicinal plant endemic to Ethiopia. It has been traditionally used to treat different infectious diseases and also in food preparation as condiment. The aim of the current study was to evaluate antibacterial and antifungal activities of water, ethanol and methanol based crude extracts of L. ... Show More
  • Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children

    Yulianty Mochtar, Nadirah Rasyid Ridha, Dasril Daud

    Issue: Volume 3, Issue 3, May 2015
    Pages: 124-127
    Received: 23 April 2015
    Accepted: 6 May 2015
    Published: 21 May 2015
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    Abstract: Introduction: Relapse in children with leukemia is a phase appearing the leukemia cells after complete remission; this situation can impact the children itself, parents and also the support system. Objective: To identify the factors related of relapse incidence in children with leukemia. Methods: This study was conducted by using a retrospective co... Show More
  • Interaction of Titanium Dioxide Nanoparticles and Blood Serum of Patients with Bronchial Asthma and Myasthenia Gravis

    Elena Arkhipova, Irina Alchinova, Alexander Sanadze, Leonid Goldenberg, Mikhail Karganov

    Issue: Volume 3, Issue 3, May 2015
    Pages: 128-132
    Received: 6 May 2015
    Accepted: 13 May 2015
    Published: 26 May 2015
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    Abstract: The interest to nanoobjects is mainly attracted by the fact that their properties (and also biological in particular interest to the project) differ drastically from the properties of either bulk material or constituent molecules. The fundamental task is correlation between structure of the nanoparticles and their interaction with surrounding media... Show More