American Journal of Clinical and Experimental Medicine

Volume 2, Issue 6, November 2014

  • The Analysis Mutation of the CARD15 Gene Variants in Chronic Periodontitis

    Asmawati Amin, Bahruddin Thalib, Mochammad Hatta

    Issue: Volume 2, Issue 6, November 2014
    Pages: 117-122
    Received: 1 October 2014
    Accepted: 17 October 2014
    Published: 30 October 2014
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    Abstract: Purpose of this study was to determine the variant of CARD 15 gene mutations with periodontitis chronic .Identified by using polymerase chain reaction (PCR) and folowed by using restriction fragment length polymorphism analysis (RFLP). CARD 15 gene mutation with chronic periodontitis were found heterozygote mutation and homozygote mutation variants... Show More
  • Comparative Effects of Exercise on Selected Cardiorespiratory Parameters among Young Adults from Different Ethnic Groups Resident in Nigeria

    Alese Ojo Oluwole, Adeosun Olukayode Isaac, Johnson Esther Olubusola, Olukiran Sesan Olaoluwa, Alese Margaret Olutayo

    Issue: Volume 2, Issue 6, November 2014
    Pages: 123-127
    Received: 10 October 2014
    Accepted: 1 November 2014
    Published: 10 November 2014
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    Abstract: This study investigated the differences or similarities in the baseline and post exercise cardiorespiratory parameters between young male adults of Igbo and Yoruba. A total of two hundred apparently healthy subjects (100 Yorubas and 100 Igbos) were involved in the study. Subjects were undergraduates who were within the age of 18-30 years. The subje... Show More
  • Constitutional Pericentric Inversion of Chromosome 9 and Chronic Myeloid Leukemia

    Salil Vaniawala, Gadhia Pankaj

    Issue: Volume 2, Issue 6, November 2014
    Pages: 128-131
    Received: 10 October 2014
    Accepted: 6 November 2014
    Published: 20 November 2014
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    Abstract: In the present study, we screened the bone marrow chromosome database entries between March, 2004 and December, 2013 to identify cases with inv(9) along with t(9;22) variations. Our study recorded 2300 cases of confirmed CML (Ph positive), of which only 12 (0.52%) cases had inv(9) and t(9;22). The association between inv(9) and t(9;22) is not fully... Show More
  • Caffeine Modulates Biliary Secretions in Indigenous Nigerian Dogs

    Kolawole Victor Olorunshola, Cheh Augustine Awasum, Nenadi Claire Hedima

    Issue: Volume 2, Issue 6, November 2014
    Pages: 132-136
    Received: 29 September 2014
    Accepted: 7 November 2014
    Published: 17 November 2014
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    Abstract: This study was aimed at evaluating the effect of caffeine on biliary secretions in indigenous Nigerian dogs. A total of 6 dogs weighing 12 – 15 kg divided into 2 groups were used. The control group was fed their normal diet and water ad libitum and the treated group received 16 mg/kg of white crystalline caffeine dissolved in 10 mls of water and ad... Show More
  • Efficacy of Topical Zinc Sulphate on Wound Healing of Experimentally Induced Skin Ulcers by Nicorandil and Induction Effect on Transforming Growth Factor-β

    Shireen Sameen, Tagreed Altaei

    Issue: Volume 2, Issue 6, November 2014
    Pages: 137-150
    Received: 5 November 2014
    Accepted: 12 November 2014
    Published: 17 November 2014
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    Abstract: Induced ulcer wound repair needs re-epithelialisation to replace necrotised and/or damaged tissue and to re-establish its integrity. Transforming growth factor-β (TGF-β) affects all cell types that are involved in all stages of wound healing. The assessment of induced ulcer wound healing activity was carried out through three models: First, excisi... Show More
  • The Effect of Arm Swing Exercise on Gait and Balance in Stroke Patients

    June-Seok Ma, Hyun-Joo Kim

    Issue: Volume 2, Issue 6, November 2014
    Pages: 151-155
    Received: 19 October 2014
    Accepted: 3 November 2014
    Published: 21 November 2014
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    Abstract: The aim of this study is investigate the effect of arm swing exercise on balance and gait in stroke patients. Group A (n=8): 0.5kg strap was applied during arm swing exercise in experimental group for 30 minutes a day, 3 times a week for 4 weeks. Group B (n=8): Subjects in control group performed neurodevelopmental treatment for 30 minutes a day, 3... Show More
  • E-Prostanoid Receptor Distribution in Airway Smooth Muscle Cells of a Rat Model of Asthma

    Yanfeng Ying, Ye Hu, Haohao Chen, Pingguang Tu

    Issue: Volume 2, Issue 6, November 2014
    Pages: 156-160
    Received: 3 November 2014
    Accepted: 13 November 2014
    Published: 23 November 2014
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    Abstract: Airway remodeling is a main pathological characteristic of asthma, and strongly associated with migration and proliferation of airway smooth muscle cells. E-prostanoid (EP) receptor can regulate airway remodeling. This study established a rat model of asthma and evaluated EP changes in airway smooth muscle cells under the asthmatic state so as to p... Show More
  • Rhabdomyolysis Associated to Glossopharyngeal Edema: A Rare Side Effect of Diclofenac

    Hicham Bakkali, Lahcen Belyamani, Salahedine Massou, Loukmane Elwartiti, Khalil Aboulaala, Hicham Balkhi, Charqui Haimeur

    Issue: Volume 2, Issue 6, November 2014
    Pages: 161-164
    Received: 21 November 2014
    Accepted: 2 December 2014
    Published: 15 December 2014
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    Abstract: Rhabdomyolysis is a widely used non steroid anti-inflammatory drug. Rhabdomyolysis after taking Diclofenac is rarely reported, and the association to a glossopharyngeal edema has never been discussed. Here is a case of rhabdomyolysis associated to glossopharyngeal edema after taking 200 mg of Diclofenac. The patient was first diagnosed with para ph... Show More
  • Clinical Adverse Events Profile during Combination Therapy with Amlodipine and Hydrochlorothiazide in Hypertensive Nigerians

    G. B. S. Iyalomhe, E. K. I. Omogbai, A. O. Isah, S. I. Iyalomhe

    Issue: Volume 2, Issue 6, November 2014
    Pages: 165-170
    Received: 6 December 2014
    Accepted: 16 December 2014
    Published: 19 December 2014
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    Abstract: Background: Combination therapy with antihypertensive drugs from different classes has been recommended as an effective strategy to attain blood pressure (BP) goal. Although amlodipine (AML) and hydrochlorothiazide (HCZ) are frequently used as combination therapy in Nigeria, information regarding the adverse events associated with this regimen is s... Show More
  • Management of Chronic Neuritis with an Extended and Continuous Course of Prednisolone and Methotrexate: A Case Report

    Delwar Hossain

    Issue: Volume 2, Issue 6, November 2014
    Pages: 171-174
    Received: 8 December 2014
    Accepted: 17 December 2014
    Published: 22 December 2014
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    Abstract: Patients may have prolonged neuritic episode in the field of leprosy. In that case, one or few interrupted courses of prednisolone of 4-months duration may prove inadequate for the unduly suffering patients. With an intention to see whether a prolonged course of prednisolone and methotrexate could be of any help for them, a patient having neuritis ... Show More