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Effect of Doxycycline in Autologous Serum to Improvement Clinical Manifestation of Acne Vulgaris
Muhlis Yunus,
Anis Irawan Anwar,
Siswanto Wahab,
Farida Tabri,
Ilhamjaya Patellongi,
Johanes Widodo
Issue:
Volume 5, Issue 2, March 2017
Pages:
30-35
Received:
25 January 2017
Accepted:
10 February 2017
Published:
1 March 2017
Abstract: Acne vulgaris (AV) is an inflammatory disease of skin on the follicle polisebasea frequent and considered dermatological problems the most common worldwide. This study investigates the relationship topical therapy using autologous serum containing doxycycline in women with moderate to severe acne vulgaris. Research conducted in Makassar, South Sulawesi, as many as 13 samples that met the inclusion criteria. Clinical examination in patients with moderate acne vulgaris to severe and based on clinical manifestations, level of sebum measured before, and levels of estradiol. All patients given the autologous serum after being given doxycycline 200 mg single dose oral which will be applied every night. Furthermore monitored on day to 14 and day to 28. The data were processed using paired Wilcoxon test. Results improvement in clinical manifestations and levels of sebum on days 14 and 28 compared to day 1 was significantly (p <0.05). There were improvements in clinical manifestations and decrease sebum levels in patients with moderate to severe AV after application of autologous serum containing doxycycline.
Abstract: Acne vulgaris (AV) is an inflammatory disease of skin on the follicle polisebasea frequent and considered dermatological problems the most common worldwide. This study investigates the relationship topical therapy using autologous serum containing doxycycline in women with moderate to severe acne vulgaris. Research conducted in Makassar, South Sula...
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Study of Para-Phenylenediamine (PPD) in the Clothes Textile Materials
Amelia Prisdiani,
Farida Tabri,
Sri Vitayani Muchtar,
Burhanuddin Bahar,
Yohanes Widodo Wirohadidjojo,
Agussalim Bukhari
Issue:
Volume 5, Issue 2, March 2017
Pages:
36-40
Received:
26 January 2017
Accepted:
10 February 2017
Published:
1 March 2017
Abstract: Atopic dermatitis is a chronic skin disease that most commonly occurs in children. The research aimed at investigating the para-phenylenenediamine (PPD) content on the textile material of the disperse blue 106 which was given the softening agent (SA). The research was conducted Biopharmaco-Laboratory of the Research Activity Centre Building, Hasanuddin University, Makassar as the place of the UV-VIS Spectrophotometer examination. The research used the experimental method to find out PPD content in the clothes textile material soaked in SA. The research result indicates that PPD content in the clothes textile material using SA is higher than the aquadest, and there is PPD increase content released by SA in line with the textile material soaking duration.
Abstract: Atopic dermatitis is a chronic skin disease that most commonly occurs in children. The research aimed at investigating the para-phenylenenediamine (PPD) content on the textile material of the disperse blue 106 which was given the softening agent (SA). The research was conducted Biopharmaco-Laboratory of the Research Activity Centre Building, Hasanu...
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Protective Effect of Cocoa Extract on Malondialdehyde Level in Ultraviolet B Induced - Albino Mice Skin
Suci Nugraeni Tahir,
Farida Tabri,
Khairuddin Djawad,
Anni Adriani,
Arifin Seweng,
Nasrum Massi
Issue:
Volume 5, Issue 2, March 2017
Pages:
41-45
Received:
27 January 2017
Accepted:
10 February 2017
Published:
1 March 2017
Abstract: The antioxidant activity in cocoa linked to the polyphenol content therein, especially subunit monomers catechin and epicatechin. The aim of the study was to determine the protective effects of cocoa extract on levels of malondialdehyde in albino mice by exposure to UVB. This study was conducted at animal laboratory to interventions UVB and Extract, Cocoa and Biomolecular laboratory of medical faculty of Hasanuddin University for the ELISA examination. This study used true experimental design with animal experimental design to assess the effectiveness of topical application cacao extract on mice skin after UVB induction for twelve weeks. The research samples were 30 head of albino mice divided into 6 groups: control 5 mice without protection and given 450 mJ UV Bexposure 3 times per week, the second group was 5 untreated controlmice, the third group was 5 mice with 100 ppm of cocoa topical extract every day and UVB 450 mJ exposure 3 times a week, the fourth group of 5 mice with 200 ppm topical cocoa extract every day and exposure to 450 mJ three times a week, the fifth group of 5 mice with 400 ppm topical cocoa extract every day and exposure to 450 mJ three times a week, the sixth group of 5 mice with 800 ppm topical everyday cocoa extract and exposure to 450 mJ three times a week, a week after termination and biopsy excisionof skin for examination of Malondialdehyde level with ELISA. The results indicated resources of 200 ppm cocoa extract Provides the best effect with reduced MDA levels with the highest protective effect Compared to other groups.
Abstract: The antioxidant activity in cocoa linked to the polyphenol content therein, especially subunit monomers catechin and epicatechin. The aim of the study was to determine the protective effects of cocoa extract on levels of malondialdehyde in albino mice by exposure to UVB. This study was conducted at animal laboratory to interventions UVB and Extract...
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The Protective Effects of Topical Cocoa Extract Lotio on Albino Mice to the Level of 8-OHdG After Ultraviolet B Exposure
Ramona Utami,
Anis Irawan Anwar,
Khairuddin Djawad,
Anni Adriani,
Siswanto Wahab,
Burhanuddin Bahar
Issue:
Volume 5, Issue 2, March 2017
Pages:
46-49
Received:
25 January 2017
Accepted:
10 February 2017
Published:
2 March 2017
Abstract: Ultraviolet B radiation (UVB) often cause oxidative stress, through the reactive oxygen species (ROS) formation and produce DNA damage. This study aims to assess the protective effects of topically cocoa extract lotio against DNA damage by measure of 8-OHdG level in albino mice after UVB exposure. This study was conducted in Makassar, South Sulawesi, using 20 Swiss albino mice, aged 6-9 weeks, weight 20-30 grams. Mice were divided into 3 groups: The first group is a control group or negative control (without cocoa extract and without UVB exposure, consist 4 mice), the second is UVB control group exposure with UVB 450mJ / cm2 three times a week for 12 weeks without topical cocoa extract (4 mice) and the third group is mice with extract cocoa 200, 400 and 800 ppm every day, 20 minutes before exposure with UVB 450mJ / cm2 three times a week for 12 weeks (each concentration of cocoa extracts consist of 4 mice). At 24 hours after last exposure all mice were terminated and excisional biopsy on the dorsal skin of the size of 1x1 cm and performed 8-OHdG ELISA. The results show there was significant difference (p <0.05) between the control group UVB with negative control and cocoa 800 ppm. The 800 ppm cocoa extract is the most effective to the reduction of 8-OhdG level.
Abstract: Ultraviolet B radiation (UVB) often cause oxidative stress, through the reactive oxygen species (ROS) formation and produce DNA damage. This study aims to assess the protective effects of topically cocoa extract lotio against DNA damage by measure of 8-OHdG level in albino mice after UVB exposure. This study was conducted in Makassar, South Sulawes...
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A Comparison Between 0,25% Tumeric Extract Cream and Grated Tumeric for Skin Discoloration
Solecha Setiawati,
Faridha Ilyas,
Farida Tabri,
Khairuddin Djawad,
Gemini Alam
Issue:
Volume 5, Issue 2, March 2017
Pages:
50-55
Received:
26 January 2017
Accepted:
10 February 2017
Published:
2 March 2017
Abstract: Turmeric has been found to have some efficacies in repairing the skin texture including its ability to enlighten the color of the skin associated to premature skin aging. This study aims to compare between the 0.25% turmeric extract cream and grated turmeric in skin color change. Samples in this study were collected from women subjects that were selected randomly and consecutively. There were 22 women subjects involved in this study that were assigned into two treatment groups: group I with one application a day and group II with two applications a day. Each subject in both groups applied 0.25% turmeric extract cream in upper right arm, control (4% Hydroquinone) in lower right and left arms, and grated turmeric in upper left arm. The treatment responses were evaluated by skin analyzer measuring the pigment number at day 0, 8, and 21. Data were analyzed statistically by Willcoxon test. Study findings indicated significant differences (p<0,05) between twice application of 0. 25% turmeric cream extract and 4% Hq at day 8 (2.30) on skin changes (pigment). There was also a significant difference (p<0,05) when comparing the 0,25 turmeric extract in twice application a day between H21-H0 and H21-H8.
Abstract: Turmeric has been found to have some efficacies in repairing the skin texture including its ability to enlighten the color of the skin associated to premature skin aging. This study aims to compare between the 0.25% turmeric extract cream and grated turmeric in skin color change. Samples in this study were collected from women subjects that were se...
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Use of Patient Preference Form to Evaluate Patients Satisfaction of OBGYN Outpatient Service in Dr. Wahidin Sudirohusodo Hospital Makassar – Indonesia
Eddy Hartono,
Shandy Suwanto Putra,
Elizabeth Catrina Jusuf,
Umar Malinta
Issue:
Volume 5, Issue 2, March 2017
Pages:
56-59
Received:
17 February 2017
Accepted:
1 March 2017
Published:
20 March 2017
Abstract: Patient satisfaction can be measured by five dimension: tangibles, realibility, responsiveness, assurance and emphaty. All of which shown from the satisfaction level of patient, especially from doctor-patient communication. Nowadays, doctor-patient communication has already shifted from paternalistic to patient centered communication, so it required efforts to improve effective communication. Patient preference form is a questionnaire which filled by the patient before meeting the doctor which contains the patient's anxiety level, the problem which is the main purpose of visitation, as well as the selection of the type of communication to be used by doctors. This study aims to know the use of patient preferences form to evaluate patient satisfaction of Obgyn outpatient service in Dr Wahidin Sudirohusodo hospital, Makassar. This was an descriptive observational study which was conducted in Obgyn outpatient service of Dr Wahidin Sudirohusodo Hospital, Makassar. The samples were 50 respondents using consecutive sampling method. The patient preference form was given to respondents before meeting doctor and given the questionnaire and interview afterward. This study revealed that 64.0% of respondents felt really anxious before the meeting, 92.0% chose friendly language than formal. 82.0% satisfied with the service and felt the anxiety degree were lowering after the meeting. 92.0% said the main purpose have been achieved but only 74.0% felt the doctor use the right language like they chose before. 90% respondents felt the patient preference form were useful. Patient preference form can be used to evaluate patient satisfaction of Obgyn outpatient service in BLU Dr Wahidin Sudirohusodo hospital, Makassar, especially improving effective doctor-patient communication. The threats and weeakness can be pressed by doctor communication training and also by adjusting patient preference form with Indonesia situation and Obgyn field.
Abstract: Patient satisfaction can be measured by five dimension: tangibles, realibility, responsiveness, assurance and emphaty. All of which shown from the satisfaction level of patient, especially from doctor-patient communication. Nowadays, doctor-patient communication has already shifted from paternalistic to patient centered communication, so it require...
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