Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children

Yulianty Mochtar; Nadirah Rasyid Ridha; Dasril Daud

doi:doi:10.11648/j.ajcem.20150303.19

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Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children

Yulianty Mochtar, Nadirah Rasyid Ridha, Dasril Daud

Published in American Journal of Clinical and Experimental Medicine (Volume 3, Issue 3)

Received: 23 April 2015 Accepted: 6 May 2015 Published: 21 May 2015

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Abstract

Introduction: Relapse in children with leukemia is a phase appearing the leukemia cells after complete remission; this situation can impact the children itself, parents and also the support system. Objective: To identify the factors related of relapse incidence in children with leukemia. Methods: This study was conducted by using a retrospective cohort study design based on medical record data from Dr. Wahidin Sudirohusodo Hospital, Makassar from December 2013 until August 2014. Study samples were children of 0 month – 18 years old diagnosed of having Acute Lymphoblastic Leukemia-L1. They are treated with chemotherapy and divided into relapse and non-relapse samples. Results: From 42 relapse and non-relapse samples, there were 35.7% (15) relapse samples and 64.3% (27) non relapse samples. Bivariate analyses revealed that among 1-10 year, there were 31.4% (11) with relapse and 68.6% (24) without relapse. Among the samples aged more than 10 years old, there were 57.1% (4) samples with relapse and 42.9% (3) samples without relapse, with p=0.225 (p>0.05). In terms of interval time from first diagnosis until the occurrence of relapse, the median value was 1.80 in 1-10 year-old group. In the group of >10 years old, the median value was 0.84 and p=0.207 (p>0.05). Conclusion: Age did not give any influence in the incidence of relapse in children with ALL-L1 and the interval time when the first diagnosed until relapse.

Published in	American Journal of Clinical and Experimental Medicine (Volume 3, Issue 3)
DOI	10.11648/j.ajcem.20150303.19
Page(s)	124-127
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Acute Lymphoblastic Leukemia-L1, Relapse, Age, Children

References

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APA Style

Yulianty Mochtar, Nadirah Rasyid Ridha, Dasril Daud. (2015). Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children. American Journal of Clinical and Experimental Medicine, 3(3), 124-127. https://doi.org/10.11648/j.ajcem.20150303.19

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ACS Style

Yulianty Mochtar; Nadirah Rasyid Ridha; Dasril Daud. Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children. Am. J. Clin. Exp. Med. 2015, 3(3), 124-127. doi: 10.11648/j.ajcem.20150303.19

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AMA Style

Yulianty Mochtar, Nadirah Rasyid Ridha, Dasril Daud. Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children. Am J Clin Exp Med. 2015;3(3):124-127. doi: 10.11648/j.ajcem.20150303.19

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@article{10.11648/j.ajcem.20150303.19,
  author = {Yulianty Mochtar and Nadirah Rasyid Ridha and Dasril Daud},
  title = {Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {3},
  number = {3},
  pages = {124-127},
  doi = {10.11648/j.ajcem.20150303.19},
  url = {https://doi.org/10.11648/j.ajcem.20150303.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20150303.19},
  abstract = {Introduction: Relapse in children with leukemia is a phase appearing the leukemia cells after complete remission; this situation can impact the children itself, parents and also the support system. Objective: To identify the factors related of relapse incidence in children with leukemia. Methods: This study was conducted by using a retrospective cohort study design based on medical record data from Dr. Wahidin Sudirohusodo Hospital, Makassar from December 2013 until August 2014. Study samples were children of 0 month – 18 years old diagnosed of having Acute Lymphoblastic Leukemia-L1. They are treated with chemotherapy and divided into relapse and non-relapse samples. Results: From 42 relapse and non-relapse samples, there were 35.7% (15) relapse samples and 64.3% (27) non relapse samples. Bivariate analyses revealed that among 1-10 year, there were 31.4% (11) with relapse and 68.6% (24) without relapse. Among the samples aged more than 10 years old, there were 57.1% (4) samples with relapse and 42.9% (3) samples without relapse, with p=0.225 (p>0.05). In terms of interval time from first diagnosis until the occurrence of relapse, the median value was 1.80 in 1-10 year-old group. In the group of >10 years old, the median value was 0.84 and p=0.207 (p>0.05). Conclusion: Age did not give any influence in the incidence of relapse in children with ALL-L1 and the interval time when the first diagnosed until relapse.},
 year = {2015}
}

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TY - JOUR
T1 - Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children
AU - Yulianty Mochtar
AU - Nadirah Rasyid Ridha
AU - Dasril Daud
Y1 - 2015/05/21
PY - 2015
N1 - https://doi.org/10.11648/j.ajcem.20150303.19
DO - 10.11648/j.ajcem.20150303.19
T2 - American Journal of Clinical and Experimental Medicine
JF - American Journal of Clinical and Experimental Medicine
JO - American Journal of Clinical and Experimental Medicine
SP - 124
EP - 127
PB - Science Publishing Group
SN - 2330-8133
UR - https://doi.org/10.11648/j.ajcem.20150303.19
AB - Introduction: Relapse in children with leukemia is a phase appearing the leukemia cells after complete remission; this situation can impact the children itself, parents and also the support system. Objective: To identify the factors related of relapse incidence in children with leukemia. Methods: This study was conducted by using a retrospective cohort study design based on medical record data from Dr. Wahidin Sudirohusodo Hospital, Makassar from December 2013 until August 2014. Study samples were children of 0 month – 18 years old diagnosed of having Acute Lymphoblastic Leukemia-L1. They are treated with chemotherapy and divided into relapse and non-relapse samples. Results: From 42 relapse and non-relapse samples, there were 35.7% (15) relapse samples and 64.3% (27) non relapse samples. Bivariate analyses revealed that among 1-10 year, there were 31.4% (11) with relapse and 68.6% (24) without relapse. Among the samples aged more than 10 years old, there were 57.1% (4) samples with relapse and 42.9% (3) samples without relapse, with p=0.225 (p>0.05). In terms of interval time from first diagnosis until the occurrence of relapse, the median value was 1.80 in 1-10 year-old group. In the group of >10 years old, the median value was 0.84 and p=0.207 (p>0.05). Conclusion: Age did not give any influence in the incidence of relapse in children with ALL-L1 and the interval time when the first diagnosed until relapse.
VL - 3
IS - 3
ER -

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Author Information

Yulianty Mochtar

Department of Pediatrics, Medical Faculty, Hasanuddin University, Makassar, Indonesia
Nadirah Rasyid Ridha

Department of Pediatrics, Medical Faculty, Hasanuddin University, Makassar, Indonesia
Dasril Daud

Department of Pediatrics, Medical Faculty, Hasanuddin University, Makassar, Indonesia

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APA Style

Yulianty Mochtar, Nadirah Rasyid Ridha, Dasril Daud. (2015). Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children. American Journal of Clinical and Experimental Medicine, 3(3), 124-127. https://doi.org/10.11648/j.ajcem.20150303.19

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ACS Style

Yulianty Mochtar; Nadirah Rasyid Ridha; Dasril Daud. Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children. Am. J. Clin. Exp. Med. 2015, 3(3), 124-127. doi: 10.11648/j.ajcem.20150303.19

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AMA Style

Yulianty Mochtar, Nadirah Rasyid Ridha, Dasril Daud. Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children. Am J Clin Exp Med. 2015;3(3):124-127. doi: 10.11648/j.ajcem.20150303.19

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@article{10.11648/j.ajcem.20150303.19,
  author = {Yulianty Mochtar and Nadirah Rasyid Ridha and Dasril Daud},
  title = {Age as a Risk Factor of Relapse Occurrence in Acute Lymphoblastic Leukemia-L1 (All-L1) in Children},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {3},
  number = {3},
  pages = {124-127},
  doi = {10.11648/j.ajcem.20150303.19},
  url = {https://doi.org/10.11648/j.ajcem.20150303.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20150303.19},
  abstract = {Introduction: Relapse in children with leukemia is a phase appearing the leukemia cells after complete remission; this situation can impact the children itself, parents and also the support system. Objective: To identify the factors related of relapse incidence in children with leukemia. Methods: This study was conducted by using a retrospective cohort study design based on medical record data from Dr. Wahidin Sudirohusodo Hospital, Makassar from December 2013 until August 2014. Study samples were children of 0 month – 18 years old diagnosed of having Acute Lymphoblastic Leukemia-L1. They are treated with chemotherapy and divided into relapse and non-relapse samples. Results: From 42 relapse and non-relapse samples, there were 35.7% (15) relapse samples and 64.3% (27) non relapse samples. Bivariate analyses revealed that among 1-10 year, there were 31.4% (11) with relapse and 68.6% (24) without relapse. Among the samples aged more than 10 years old, there were 57.1% (4) samples with relapse and 42.9% (3) samples without relapse, with p=0.225 (p>0.05). In terms of interval time from first diagnosis until the occurrence of relapse, the median value was 1.80 in 1-10 year-old group. In the group of >10 years old, the median value was 0.84 and p=0.207 (p>0.05). Conclusion: Age did not give any influence in the incidence of relapse in children with ALL-L1 and the interval time when the first diagnosed until relapse.},
 year = {2015}
}

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