Abstract: A new series of bidentate nitrogen donor type Schiff bases (L1)-(L3) were prepared by the condensation reaction of ethylene-1, 2-diamine with 3, 4, 6-trimethylacetophenone, 2-aminoacetophenone and 2, 4-dimethylacetophenone in 1:2 molar ratio. The ligands were further coordinated with Co(II), Cu(II), Ni(II) and Zn(II) metals to produce their new metal complexes having an octahedral geometry. These compounds were characterized on the basis of their physical, spectral and analytical data. Elemental analysis and spectral data of the uncomplexed ligands and their metal(II) complexes were found to be in good agreement with their structures, indicating high purity of all the newly synthesized compounds. All ligands and their metal complexes were screened for antimicrobial activity. The results of antimicrobial activity indicated that metal complexes have significantly higher activity compared to their corresponding ligands. This higher activity might be due to chelation process which reduces the polarity of metal ion by coordinating with ligands.Abstract: A new series of bidentate nitrogen donor type Schiff bases (L1)-(L3) were prepared by the condensation reaction of ethylene-1, 2-diamine with 3, 4, 6-trimethylacetophenone, 2-aminoacetophenone and 2, 4-dimethylacetophenone in 1:2 molar ratio. The ligands were further coordinated with Co(II), Cu(II), Ni(II) and Zn(II) metals to produce their new met...Show More
