Journal of Drug Design and Medicinal Chemistry

Archive

Volume 1, Issue 2, December 2015

  • Synthesis and Biological Evaluation of 2-Mercaptobenzimidazole Derivatives as Anti-inflammatory Agents

    Saumya Gupta, Surya Prakash Gupta, Neeraj Upmanyu, Gopal Garg

    Issue: Volume 1, Issue 2, December 2015
    Pages: 12-16
    Received: 9 November 2015
    Accepted: 23 December 2015
    Published: 25 December 2015
    DOI: 10.11648/j.jddmc.20150102.11
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    Abstract: A series of 2-mercaptobenzimidazole derivatives (MB1–MB5) were synthesized by mannich reaction. The purity of synthesized compounds were determined by melting point and TLC and their structure was established by various analytical techniques such as IR and 1HNMR spectral studies. The newly synthesized compounds were screened for anti-inflammatory a... Show More
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  • Antimicrobial Potential of Glycyrrhiza glabra

    Asad Abbas, Muhammad Zubair, Nasir Rasool, Komal Rizwan

    Issue: Volume 1, Issue 2, December 2015
    Pages: 17-20
    Received: 14 November 2015
    Accepted: 9 December 2015
    Published: 4 January 2016
    DOI: 10.11648/j.jddmc.20150102.12
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    Abstract: This study was carried out to evaluate the antimicrobial activity of methanolic extract and different fractions (n-butanol, ethyl acetate, chloroform and n-hexane) of Glycyrrhiza glabra root. The antimicrobial activity was determined by the disc diffusion method and minimum inhibitory concentration (MIC) against a panel of microorganisms (four bact... Show More
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