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Smartphone-Based Ammonium Ion Biosensor for Sweat Analysis
Issue:
Volume 7, Issue 2, April 2019
Pages:
61-64
Received:
18 April 2019
Published:
23 May 2019
Abstract: In this article, we present a smartphone-based biosensor for detection of the ammonium ion in sweat. The sensing system consists of a sample collection chip, an ammonium ion selective electrode by screen printing, a potential reading chip and a smartphone. When the sweat flows through the sensitive membrane, a membrane potential is generated which can be captured by the potential reading chip linked with the smartphone. The potential signal was then converted to concentration value by a calibration curve. The detection can be achieved within one minute with good repeatability, and the level of the ammonium ion in sweat can reflect the body state during exercise.
Abstract: In this article, we present a smartphone-based biosensor for detection of the ammonium ion in sweat. The sensing system consists of a sample collection chip, an ammonium ion selective electrode by screen printing, a potential reading chip and a smartphone. When the sweat flows through the sensitive membrane, a membrane potential is generated which ...
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Using NGS Technology for Transcriptome Comparison of Normal and Tumor Tissues in Colorectal Cancer Patients
Issue:
Volume 7, Issue 2, April 2019
Pages:
65-71
Received:
22 April 2019
Published:
23 May 2019
Abstract: Colorectal cancer is a kind of malignant tumor, which results from life habits and genetic factors. This research project is called "Using NGS Technology for Transcriptome Comparison of Normal and Tumor Tissues in Colorectal Cancer Patients", which belongs to basic research. Next-generation sequencing technology (NGS), also known as high-throughput sequencing technology, can comprehensively obtain whole genome and transcriptome information of cells and tissues through experimental operations including DNA or RNA extraction, purification, library construction, and bioinformatics analysis; in this way, NGS can screen the mutation and abnormal expression of tumor genes and provide relatively accurate therapeutic targets as the guidance of medication. In this study, the transcriptome of five pairs of tumor tissue samples (t: tumor) and normal tissue samples (n: normal) from five patients with colorectal cancer were compared by NGS: the total RNA from those tissues were extracted to construct mRNA library, from which cancer-related transcriptome information was obtained through NGS-based RNA-seq technology and bioinformatics analysis, which may guide clinical research and treatment. The RNA-seq data of transcriptome information from the colorectal cancer patients reflected variably expressed pattern in the comparison of CRCs/normal tissue pairs; two notable targets, COL1A1 and SPP1, were consistent with two other previous researches and matched pathways enrichment with one of them.
Abstract: Colorectal cancer is a kind of malignant tumor, which results from life habits and genetic factors. This research project is called "Using NGS Technology for Transcriptome Comparison of Normal and Tumor Tissues in Colorectal Cancer Patients", which belongs to basic research. Next-generation sequencing technology (NGS), also known as high-throughput...
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An Investigation of Acute Gastroenteritis Outbreak Caused by Norovirus GII Infection in a University
Yapin Li,
Huisuo Yang,
Haiyang Zhang,
Min Wang,
Qingfeng Li,
Jian Wang,
Wenjing Song,
Dongqi Gao
Issue:
Volume 7, Issue 2, April 2019
Pages:
72-77
Received:
19 January 2019
Published:
23 May 2019
Abstract: Objective: To investigate an acute gastroenteritis epidemic in a university and to identify the scale, to find the possible causes of the outbreak. Methods: The field epidemiological survey method was used for information collection. Case-control and retrospective cohort study methods were used. The database was established with SPSS 25.0 and statistical analysis was performed. Results: In January 2018, an outbreak of acute gastroenteritis occurred in a university. A total of 162 cases were found and the attack rate was 8.94% (162/1813), all of whom were students. All the cases were eaten in the same student canteen. Case-control studies showed that on January 10th, lunch braised pork ribs, 10th dinner tomato scrambled eggs, and 11th dinner cakes were suspicious food. Norovirus nucleic acid was detected in the anal swab and fecal specimens of the case and canteen staff, all of which were GII type. The investigation found that there was no hand washing facility in the student canteen. The staff in the canteen did not wear masks, hats and gloves in the operation. The kitchen had no tableware disinfection cabinet, and the canteen detected 4 cases of Norovirus nucleic acid positive. Conclusions: This epidemic was an outbreak of acute gastroenteritis caused by Norovirus GII infection in a university. It is recommended to strengthen the management of food workers, strictly check the medical examination before taking up the post, strictly apply the fake sales system, and regularly check the personnel who have symptoms related to the gastrointestinal tract. Purchase food cabinet disinfection cabinets, disinfect food utensils in strict accordance with the operating procedures; add hand washing facilities in the cafeteria; change the table meal method into a meal method. Conduct health education for students and develop good health habits.
Abstract: Objective: To investigate an acute gastroenteritis epidemic in a university and to identify the scale, to find the possible causes of the outbreak. Methods: The field epidemiological survey method was used for information collection. Case-control and retrospective cohort study methods were used. The database was established with SPSS 25.0 and stati...
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Experimental Study on Autism Caused by Prenatal Exposure to Plasticizer DEHP
Boyang Hu,
Yiting Song,
Genan Liang,
Yihuan Shao,
Linling Qi,
Xue Jiang,
Yuemin Ding
Issue:
Volume 7, Issue 2, April 2019
Pages:
78-81
Received:
5 March 2019
Published:
23 May 2019
Abstract: Objective: Epidemiological studies have found that exposure to plasticizers in the environment may be associated with autism in preschool children, but laboratory evidence is lacking. To determine whether prenatal exposure to DEHP, a plasticizer, causes autism in offspring mice. Methods: Pregnant mice were randomly divided into four groups: corn oil control group and low, medium and high concentration DEHP exposure group (10 mg/kg, 50 mg/kg, 250 mg/kg). Mice were received continuous intragastric administration of DEHP from the 3rd day to the 17th day of pregnancy. Behavioral characteristics of autism in offspring were assessed after birth. Results: The social ability of offspring was significantly decreased after prenatal exposure to moderate and high concentration DEHP. The female offspring showed repetitive stereotyped behavior and decreased spontaneous activities. Conclusion: Exposure to medium and high concentration of DEHP during embryonic stage can induce autism in offsprings.
Abstract: Objective: Epidemiological studies have found that exposure to plasticizers in the environment may be associated with autism in preschool children, but laboratory evidence is lacking. To determine whether prenatal exposure to DEHP, a plasticizer, causes autism in offspring mice. Methods: Pregnant mice were randomly divided into four groups: corn oi...
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The Effect and Evaluation of Video Intervention and Education on Stress and the Effect of Operation of Patients Undergoing Oral Maxillofacial Operation
Tao Ran,
Zhang Yifang,
Huang Minfeng,
Li Jianan
Issue:
Volume 7, Issue 2, April 2019
Pages:
82-86
Received:
11 April 2019
Published:
23 May 2019
Abstract: Objective: To evaluate the effect of video intervention and education on anxiety and pressure of patients undergoing oral maxillofacial operation. Method: a total of 96 patients were randomly divided into the experimental and control group, with 48 patients in each group. The control group were given routine intervention and education while the experimental group were given video intervention and education.The Zung Self-Rating Anxiety scale (SAS) and the Zung Self-Rating Anxiety scale (SDS) were used to evaluate the anxiety and depression degree of all patients one day before operation.The Visual Analogue Scale (VAS) and Dental visit satisfaction scale (DVSS) were used to assess the pain and satisfaction of all patients after operation one day after operation. Results: The SAS score of two group at 1 day before operation is (the control group: 11.52±1.93, the experimental group: 11.66±2.01).There is no statistical significance between two groups.The SDS score of two group at 1 day before operation is (the control group:13.78±2.92, the experimental group:13.89±3.02). There is no statistical significance between two groups. After video intervention and education, The SAS score of two groups is (the control group:11.36±1.90, the experimental group: 7.85±1.00), The SDS score of two groups is (the control group:13.10±2.85, the experimental group:8.46±1.51),there is significant difference between results of two groups (p < 0.05); the twice SAS and SDS score of the control group before one day of operation show have no statistical difference. The VAS score of two group at 1 day after operation is (the control group:6.28±1.13, the experimental group: 3.86±0.78).There is statistical significance between two groups (p < 0.05). The DVSS score of two group after operation is (the control group:70%, the experimental group: 91%). There is statistical significance between two groups (p < 0.05). Conclusion: The video intervention and education can effectively relieve pressure of patients undergoing oral maxillofacial operation. Furthermore, it can also improve the effect of operation.
Abstract: Objective: To evaluate the effect of video intervention and education on anxiety and pressure of patients undergoing oral maxillofacial operation. Method: a total of 96 patients were randomly divided into the experimental and control group, with 48 patients in each group. The control group were given routine intervention and education while the exp...
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Meet the Needs of Reservoir Identification Research of Atypical Archie Phenomenon
Wenqiang Tang,
Kun Xiong,
Chen Pan,
Haoting Xing,
Wei Chen,
Xuan Liu,
Xinxin Zang,
Yun Yang
Issue:
Volume 7, Issue 2, April 2019
Pages:
87-91
Received:
2 April 2019
Published:
23 May 2019
Abstract: According to the core data, the characteristics of resistivity variation under different porous structure and wettability are studied and explained theoretically. It is concluded that with the increase of porous structure exponent m, the resistivity increases significantly with the same saturation, and the influence is beyond imagination. With the increase of saturation index n, the resistivity increases with the same saturation. If all fixed m and n values are used to calculate the water saturation of the reservoir, the water saturation result will be very high and the hydrocarbon reservoir will be ignored. This change feature is of great guiding significance to the identification of hidden oil and gas reservoir satisfying the atypical Archie formula.
Abstract: According to the core data, the characteristics of resistivity variation under different porous structure and wettability are studied and explained theoretically. It is concluded that with the increase of porous structure exponent m, the resistivity increases significantly with the same saturation, and the influence is beyond imagination. With the ...
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Experimental Study on Rock Fragmentation Efficiency of Two Stage PDC Bit
Wang Bin,
Guan Zhichuan,
Hu Huaigang,
Pan Rui
Issue:
Volume 7, Issue 2, April 2019
Pages:
92-97
Received:
8 April 2019
Published:
23 May 2019
Abstract: This paper proposes a two-stage PDC bit that can actively release the formation pressure in advance to improve the rock breaking efficiency, and provides a new solution for effectively improving the rock breaking efficiency of the deep hard formation. The red sandstone drilling comparison experiment under the same drilling parameters of the two-stage PDC bit and the conventional PDC bit is carried out. The experimental results show that the two-stage PDC bit can effectively improve the rock breaking efficiency under the same conditions and compare with the conventional PDC bit. The speed increase efficiency can be up to 90%; the use of two-stage drill can greatly reduce the rock breaking torque during the drilling process. Under the same working conditions, the double-stage PDC bit can reduce the rock breaking torque by up to 30%, and the two-stage The mechanical specific energy of the drill bit is generally lower than the mechanical specific energy of the conventional drill bit, and the relative reduction of the mechanical specific energy under the same conditions is between 5% and 25%. And effectively reduce the ineffective vibration of the drill bit, thereby achieving the purpose of protecting the drill bit and increasing the life of the combination of the drill bit and the bottom drill.
Abstract: This paper proposes a two-stage PDC bit that can actively release the formation pressure in advance to improve the rock breaking efficiency, and provides a new solution for effectively improving the rock breaking efficiency of the deep hard formation. The red sandstone drilling comparison experiment under the same drilling parameters of the two-sta...
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Features of Atmospheric Pollutant in Beijing Region from 2014 to 2017
Tang Xiru,
Xu Liping,
Liu Shufu,
Shen Chunming,
Wang Bin,
Long Tao
Issue:
Volume 7, Issue 2, April 2019
Pages:
98-106
Received:
10 April 2019
Published:
23 May 2019
Abstract: In order to find effective ways to control atmospheric environment, this paper mainly studies the Spatial-temporal features of atmospheric pollutant distribution in the past 2014-2017 years. The particulate matter concentration was retrieved by remote sensing data and all data would be processed by Kriging method. The results show that most pollutant concentration decreased, especially SO2, PM2.5 and PM10, though the ozone problem is beginning to stand out; In addition, CO concentration in different regions varies in different seasons, meanwhile other pollutants do not like this.
Abstract: In order to find effective ways to control atmospheric environment, this paper mainly studies the Spatial-temporal features of atmospheric pollutant distribution in the past 2014-2017 years. The particulate matter concentration was retrieved by remote sensing data and all data would be processed by Kriging method. The results show that most polluta...
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Full-Field Strain Analysis of Porous Membrane Under Biaxial Tension
Wang Wei,
Xu Xiaochen,
Xu Zhihong
Issue:
Volume 7, Issue 2, April 2019
Pages:
107-114
Received:
25 March 2019
Published:
23 May 2019
Abstract: In this paper, the full-field strain and strain concentration factor around the hole of PTFE membrane under uniaxial biaxial tension are studied based on digital image speckle (DIC) technique and finite element calculation.Through the load-strain curve of porous membrane during tension, three stages of properties of membrane during biaxial tension are obtained: elastic stage, plastic stage and failure stage.The relationship between the maximum strain around the pore, the ultimate bearing capacity of the membrane and the pore size is obtained. The relationship between the strain concentration factor at the pore edge and the pore size is obtained.The results show that the larger the pore size, the more obvious the strain concentration around the pore and the smaller the ultimate load it can bear, and the greater the strain concentration coefficient around the pore, the more easily the membrane is damaged.
Abstract: In this paper, the full-field strain and strain concentration factor around the hole of PTFE membrane under uniaxial biaxial tension are studied based on digital image speckle (DIC) technique and finite element calculation.Through the load-strain curve of porous membrane during tension, three stages of properties of membrane during biaxial tension ...
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Pilot Study on Reverse Osmosis Concentrate of PTA Wastewater by O3-BAC
Issue:
Volume 7, Issue 2, April 2019
Pages:
115-118
Received:
4 April 2019
Published:
23 May 2019
Abstract: This paper studies the effectiveness of the "O3-BAC" composite process in the treatment of the reverse osmosis concentrate of the PTA wastewater, and provides an important basis for the industrialization practice of the treatment of the reverse osmosis concentrate of the PTA wastewater.A pilot test was conducted in a petrochemical PTA sewage treatment plant in JiangSu province using the ozone-biological activated carbon combination process, to investigate the effect of the process on the deep treatment of PTA reverse osmosis concentrated water under the design parameters.The experiment showed that when the pH was 8 ~ 9, the ozone injection amount was 60mg/L, the oxidation contact time was 90min. the BAC adsorption time was 60min.after processing, the CODCr is less than 60mg/L. The effluent quality can meet the direct emission standard of petrochemical industry GB31571-2015.The experimental results show that the combination process is stable for the treatment of reverse osmosis concentrate of the PTA wastewater.
Abstract: This paper studies the effectiveness of the "O3-BAC" composite process in the treatment of the reverse osmosis concentrate of the PTA wastewater, and provides an important basis for the industrialization practice of the treatment of the reverse osmosis concentrate of the PTA wastewater.A pilot test was conducted in a petrochemical PTA sewage treatm...
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Research Progress of Oil Refining Wastewater Treatment Technology at Home and Abroad
Issue:
Volume 7, Issue 2, April 2019
Pages:
119-125
Received:
8 April 2019
Published:
23 May 2019
Abstract: Refining wastewater is difficult to treat because of its high pollutants concentration, complex composition, poor biodegradability,and often contains toxic and harmful substances. This paper introduces the sources and characteristics of refinery wastewater and the main treatment status of refinery wastewater, which is the tertiary treatment method of refinery wastewater. In this paper, the latest research progress of refinery wastewater treatment technology in domestic and foreign research institutions in recent years is reviewed, especially the research progress of advanced oxidation membrane separation method and artificial wetland method. At the same time, the development prospect of refining wastewater treatment technology is prospected, and the research direction in this field is put forward.
Abstract: Refining wastewater is difficult to treat because of its high pollutants concentration, complex composition, poor biodegradability,and often contains toxic and harmful substances. This paper introduces the sources and characteristics of refinery wastewater and the main treatment status of refinery wastewater, which is the tertiary treatment method ...
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Implementation of Data Conversion Interface Between Midas and DUT2014 Structural Model
Xu Ji,
Zhinan Ren,
Zhe Qi,
Zheng He
Issue:
Volume 7, Issue 2, April 2019
Pages:
126-133
Received:
28 April 2019
Published:
23 May 2019
Abstract: DUT2014 is a computational program developed by our team for the elastic-plastic time history analysis of super high-rise building structures. The integrated platform code is open source, which has all the materials and elements for the structural analysis of super high-rise buildings. Moreover, the integrated platform has a new element state transition algorithm (STP), which greatly improves the computational efficiency of elastic-plastic time history analysis. Midas is a finite element analysis software, which has good elastic analysis function and non-linear analysis function, and it has good pre-processing function. Preprocessing of DUT2014 is a command stream format in text format, and its modeling function is relatively cumbersome. In order to realize the customization of DUT2014 modeling function, this paper decided to develop an interface program to transform Midas model data file to DUT2014 model data file. This paper establishes an interface program for converting Midas structured data model file into DUT2014 structured data model file by using Microsoft Visual C++ programming program. In order to verify the correctness of structural data model transformation, this paper will use interface program to transform three different scale structures, and then verify the accuracy of the interface by comparing the quality information, modal calculation results, elastic time history response and elastic-plastic time history response of the model before and after transformation.
Abstract: DUT2014 is a computational program developed by our team for the elastic-plastic time history analysis of super high-rise building structures. The integrated platform code is open source, which has all the materials and elements for the structural analysis of super high-rise buildings. Moreover, the integrated platform has a new element state trans...
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