Abstract: It is known from previous works that about a third of men and almost half of women are sensitive to changes in weather conditions. Approximately 65 - 75% of patients with cardiovascular diseases suffer from weather sensitivity. These patients may be dependent on atmospheric variations in temperature and pressure, relative humidity, and geomagnetic activity. In recent years, the dependence f weather-sensitive people on geomagnetic perturbation has been reliably established. The purpose of our research was to find out correlations between Earth and cosmic weather factors and hemodynamics parameters alongside therapy with IATE (prestarium, noliprel) and BRA2 (lozap, Losartan, lorista, blocktran) in elderly patients with arterial hypertension stage 3, degree 3 and influence of terrestrial factor on hypotensive effect. 185 elderly patients with arterial hypertension were examined, including 79 men and 106 women between the ages of 60 to 88. The task: to investigate the results of treatment of elderly patients with hypertensive disease stage 3, degree 3 of IATE and BRA 2 in the gender aspect and to test the effectiveness of the receiving hypotensive therapy alongside meteorological (atmospheric temperature, humidity, atmospheric pressure) and geomagnetic factors (geomagnetic activity expressed by the total planetary Kp-index). It is known that the cardiovascular system parameters are influenced by the parameters of terrestrial and space weather. Despite a large number of studies on the role of fluctuations in weather factors on cardiovascular parameters, this question has not been examined in the gender aspect in elderly patients with hypertensive disease stage 3 degree 3. We demonstrated the influence of changes in atmospheric temperature, air pressure, humidity and Kp-index of geomagnetic activity on heart rate and arterial blood pressure alongside therapy with IATE and BRA2 in elderly women and men, suffering from hypertensive disease stage 3. There were no differences in hypotensive effect of IATE between women and men. But there were differences in hypotensive effect of BRA2 between women and men.Abstract: It is known from previous works that about a third of men and almost half of women are sensitive to changes in weather conditions. Approximately 65 - 75% of patients with cardiovascular diseases suffer from weather sensitivity. These patients may be dependent on atmospheric variations in temperature and pressure, relative humidity, and geomagnetic ...Show More