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Effects of Qishenyiqi Dripping Pill on Pulmonary Function in Chronic Obstructive Pulmonary Disease
Issue:
Volume 4, Issue 1, January 2016
Pages:
1-4
Received:
28 December 2015
Accepted:
18 January 2016
Published:
31 January 2016
Abstract: Objective: To investigate the effects of Qishenyiqi Dripping Pill (QDP) on pulmonary function in patients with chronic obstructive pulmonary disease (COPD). Methods: 97 patients with chronic obstructive pulmonary disease admitted to the general wards of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital randomized plus into experimental group (53 cases) and control group (44 cases) from October 2014 to November 2015. Twice daily QDP 1000mg for experimental group based on the treatment of control group in this study, pulmonary function of two groups was compared. Results: After treatment, FEV1 from 1.36±0.12L to1.60±0.22L in experimental group, and from 1.42±0.25 to 1.51±0.16L in control group. More statistically significant was found in experimental group, P value<0.05. FEV1/FVC from 56.3±6.39% to 64.32±5.21% in experimental group, and from 56.8±8.84% to 57.33±6.56% in control group. More statistically significant was found in experimental group, P value<0.05. MMEF from 56.80±18.22% to 67.45±7.55% in experimental group, and from 55.39±20.12% to 60.22±6.01% in control group. More statistically significant was found in experimental group, P value<0.05. Conclusions: Qishenyiqi Dripping Pill can significantly improved pulmonary function of patient with chronic obstructive pulmonary disease.
Abstract: Objective: To investigate the effects of Qishenyiqi Dripping Pill (QDP) on pulmonary function in patients with chronic obstructive pulmonary disease (COPD). Methods: 97 patients with chronic obstructive pulmonary disease admitted to the general wards of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital randomized plus into ...
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Interleukin-17 in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients: Correlation with Clinical Presentation, Laboratory Parameters and Activity Indices
Eman Hassan Elsayed Hassan,
Riham Fadl Moftah
Issue:
Volume 4, Issue 1, January 2016
Pages:
5-11
Received:
16 January 2016
Accepted:
26 January 2016
Published:
16 February 2016
Abstract: Serum interleukin (IL)-17 concentrations have been reported to be increased in systemic lupus erythematosus (SLE), but associations with clinical characteristics are not well understood. Autoimmune diseases such as rheumatoid arthritis (RA), classically believed to be Th1-mediated, are predominantly driven by a Th17 immune response. The aim of the work is to compare the serum levels of IL-17 in patients with SLE and RA, it is correlation with clinical presentations, laboratory findings and disease activity in both diseases. The study was carried out on 3 groups. Group I: 20 patients with SLE. Group II: 20 patients with RA. Group III: 10 of age and sex matched healthy subjects as a control group. In this study, there were no statistical significant differences between the three studied groups regarding disease duration, disease activity, laboratory investigations (except HB, WBC and platelet count). The mean serum level of IL-17 were 173.2±52.11, 82.6±48.17 and 73.07±41.05 for group I (SLE), II (RA) and III (Control) respectively, group I has values statistically higher than other groups, and group II has values statistically higher than group III. Serum IL-17 level was significantly higher in SLE patients compared to healthy group. We concluded that, Serum IL-17 concentration correlates with SLE and RA diseases activity but is significantly elevated in patients with SLE disease. The association of other cytokines with serum IL-17 suggests that IL-17 may drive activation of diverse immune pathways in SLE and RA.
Abstract: Serum interleukin (IL)-17 concentrations have been reported to be increased in systemic lupus erythematosus (SLE), but associations with clinical characteristics are not well understood. Autoimmune diseases such as rheumatoid arthritis (RA), classically believed to be Th1-mediated, are predominantly driven by a Th17 immune response. The aim of the ...
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Demographic Presentation, Activity Indices, Damage Index: Comparative Study Between Pediatric Lupus Erythematosus Versus Adult Systemic Lupus Erythematosus in Sample Egyptian Population
Eman Hassan Elsayed Hassan,
Amira Hassan El-Gerby
Issue:
Volume 4, Issue 1, January 2016
Pages:
12-18
Received:
16 January 2016
Accepted:
26 January 2016
Published:
16 February 2016
Abstract: Systemic lupus erythematosus (SLE) is a complex autoimmune disease that can affect all organ systems due to alterations of both the innate and adaptive immune systems. Although onset during infancy is rare, the incidence of SLE rises steadily during childhood until mid-adulthood, especially among females. In this study we aimed to highlight the possible discrepancies in clinical presentations as well as serological profiles of pediatric and adult onset SLE patients, we also focused attention on the disease assessment by SLE activity index (SLE DDI) and damage index at time of presentation. Subjects were subdivided into 2 groups: Group I: A total of 92 Pediatric systemic lupus erythematosus (pSLE) that were selected from the students attending the school children hospital of medical health insurance. Group II: A total of 90 adult systemic lupus erythematosus (aSLE) patients and were recruited from those attending the Alexandria Main University Hospital and outpatient clinic. All patients were subjected to: detailed history taking and complete physical and mental examination, also activity indices as well as damage index were applied for every lupus patient of the studied groups, laboratory investigations were done for all patients. Our results demonstrated that, regarding mucocutaneous manifestations: pSLE patients have values higher than aSLE patients regarding photosensitivity (63.3% and 61.1%) and vascular lesions (23.9% and 22.2%) respectively. Regarding haematological manifestations: pSLE patients have values higher than aSLE patients regarding anemia (86.96% and 84.4), leucopenia (28.3% and 22.22) and thrombocytopenia (46.7% and 25.56%) respectively. Regarding renal abnormalities, pSLE patients have higher incidence of nephritic syndrome than aSLE patients. Regarding SLEDAI, pSLE patients have values statistically higher than aSLE patients. Regarding SLAM, pSLE patients have values statistically higher than aSLE patients, while no differences of damage index was noticed.
Abstract: Systemic lupus erythematosus (SLE) is a complex autoimmune disease that can affect all organ systems due to alterations of both the innate and adaptive immune systems. Although onset during infancy is rare, the incidence of SLE rises steadily during childhood until mid-adulthood, especially among females. In this study we aimed to highlight the pos...
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Procalcitonin as a Biomarker of Severity Degree in Sepsis Due to Pneumonia
Agus Prima,
Wachyoe Hadi Saputra
Issue:
Volume 4, Issue 1, January 2016
Pages:
19-23
Received:
4 February 2016
Accepted:
16 February 2016
Published:
29 February 2016
Abstract: Measuring PCT level can be as the examination having the role to differ the systemic inflammatory response syndrome (SIRS) and sepsis. This study aims to know the PCT level in accessing the sepsis degree at pneumonia patients. This study was an analytical study with cross-sectional design. There were 30 samples obtained since February 2013 until March 2014 at the Emergency Room and Inpatient Room of Internal Medicine Local Public Hospital Dr. Zainoel Abidin Banda Aceh. The sample collection was conducted with quota sampling technique. The data was analysed with Anova and followed with LDS. The data was considered to be significant if the p value is < 0,05. The study results were obtained the minimum limit value of PCT level at pneumonia of 0,091 ng/dl, sepsis of 0,686 ng/dl, severe sepsis of 3,593 ng/dl and shock sepsis of 21,703 ng/dl. The analysis results showed that the higher PCT level makes the higher disease severity.
Abstract: Measuring PCT level can be as the examination having the role to differ the systemic inflammatory response syndrome (SIRS) and sepsis. This study aims to know the PCT level in accessing the sepsis degree at pneumonia patients. This study was an analytical study with cross-sectional design. There were 30 samples obtained since February 2013 until Ma...
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