CNS-Antidepressant Activity of Crude Extracts and Different Fractions of Stem Bark of Acacia Nilotica
Md. Mamun-Or-Rashid,
Muhammad Ashiqul Islam,
Taniya Idris,
Md. Shah Amran
Issue:
Volume 1, Issue 2, December 2017
Pages:
13-19
Received:
16 June 2017
Accepted:
5 July 2017
Published:
16 August 2017
DOI:
10.11648/j.pst.20170102.11
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Abstract: According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude methanolic extract of Acacia nilotica bark with different soluble partitionates were subjected to investigate for the evaluation of analgesic, hypoglycemic, CNS depressant and antidiarrheal activity on mice and thrombolytic, antihelmentic, antimicrobial, antioxidant along with cytotoxicity different in vivo experiment. The crude methanolic extract of bark of Acacia nilotica were evaluated for antidepressant activity showed insignificant value.
Abstract: According to the World Health Report, approximately 450 million people suffer from a mental or behavioral disorder. This amounts of 12.3% of the global burden of disease, and will rise to 15% by 2020. Depression is most prevalent mental disorder and it is recognized to be symptomatically, psychologically and biologically heterogeneous. The crude me...
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The Role of Door Handles in the Spread of Microorganisms of Public Health Consequences in University of Benin Teaching Hospital (UBTH), Benin City, Edo State
Augustine Brian Odigie,
Frederick Osaro Ekhiase,
Paul Ikechukwu Orjiakor,
Sunday Omozuwa
Issue:
Volume 1, Issue 2, December 2017
Pages:
20-21
Received:
19 June 2017
Accepted:
3 July 2017
Published:
9 August 2017
DOI:
10.11648/j.pst.20170102.12
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Abstract: This study was aimed at investigating the microbial loads of surfaces of door handles at University of Benin Teaching Hospital (UBTH) with a view to understanding their roles in the transmission of pathogenic microorganisms. Eleven (11) sampling units were identified and used for the study. They included: Emergency Ward, Paediatric Ward, Male and Female Surgical Ward, Intensive Care Unit, Theatre Ward, Consultancy Outpatient Department (COPD), Microbiological Laboratory, Revenue Section, Pharmacy Department, and General Toilet. The samples were collected with the aid of sterile swab sticks moistened with sterile normal saline for a period of Six Months (May 2015 – October 2015) and analyzed using standard microbiological methods. Surfaces of door handles of General toilet, Paediatric Ward and Theatre Ward generally had the highest viable bacterial counts, which ranged from 4.03 ± 0.32 - 4.17 ± 0.27 × 104cfu/cm2, while the Intensive Care Unit, Male Surgical Ward and Microbiological Laboratory recorded the least bacterial load that ranged from 3.03± 0.03 - 3.30 ± 0.21 × 104cfu/cm2. The bacterial isolates were Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae, Bacillus subtilis, and Escherichia coli. The most predominant bacterial isolate was E. coli (92.00%), while B. subtilis (60.01%) was the least. Statistical analysis revealed significant correlation (p<0.05) between bacterial isolates and door handles at different sampling units. Findings from this study suggest that hospital door handles harbor a significant variety of pathogenic and non-pathogenic microorganisms of public health value, and thus could act as potential fomites for communicable diseases dissemination. Health-care workers, patients and visitors are encouraged to pay greater attention to personal hygiene practices to avoid the incidence and spread of hospital acquired infections.
Abstract: This study was aimed at investigating the microbial loads of surfaces of door handles at University of Benin Teaching Hospital (UBTH) with a view to understanding their roles in the transmission of pathogenic microorganisms. Eleven (11) sampling units were identified and used for the study. They included: Emergency Ward, Paediatric Ward, Male and F...
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