Tuberculosis Unexpectedly Presented Along Gastrointestinal Tract in Surgical Ward
Noori H. Jasim,
Hashim S. Khayat
Issue:
Volume 5, Issue 1, February 2017
Pages:
1-7
Received:
3 February 2017
Accepted:
21 February 2017
Published:
15 March 2017
Abstract: Little is known in our country particularly in Basra about tuberculous lesions affecting the gastrointestinal tract specifically solid and hallow organs such as liver, pancreas, stomach or intestine. Hence, this study aimed to report, describe and study these cases. The current study is retrospectively studied 12 patients who got tuberculous lesions along the gastrointestinal tract over the last 2 decades in Basra General Hospital (2 of them were gastric, 3 hepatic, 3 pancreatic, 3 small intestinal; one of them affecting duodenojejunal flexure, and lastly 1 perianal sinus ulcerating the nearby skin). All those patients underwent the required surgical operations. In all those patients, TB was diagnosed postoperatively by histopathology and all of them received anti-tuberculosis triple therapy for 6 months including INH, Rifampicin and Ethambutol. A long term scheduled follow up was done showing that all of them were improved except one elderly patient with TB pancreatitis died at early postoperative period. None of these cases effected with pulmonary tuberculosis previously or concomitantly. One case of hepatic tuberculosis had cervical and intra-abdominal lymphadenopathy. It is of interest to mention that extrapulmonary TB in solid and hallow organs of gastrointestinal tract should be considered when evaluating patients with gastrointestinal presentations and lesions such as ulcer, mass, abscess or perianal fistula in endemic areas and the potential for affecting these organs (along gastrointestinal tract) should be kept in mind and accounted for.
Abstract: Little is known in our country particularly in Basra about tuberculous lesions affecting the gastrointestinal tract specifically solid and hallow organs such as liver, pancreas, stomach or intestine. Hence, this study aimed to report, describe and study these cases. The current study is retrospectively studied 12 patients who got tuberculous lesion...
Show More
Severe Trauma Complications Prediction by Biomarkers
Ling Zeng,
Jian-xin Jiang
Issue:
Volume 5, Issue 1, February 2017
Pages:
8-14
Received:
9 February 2017
Accepted:
28 February 2017
Published:
20 March 2017
Abstract: Trauma and its severe complications are major health problems and leading causes of mortality and morbidity among young people in the world. The increasing ability to keep most trauma patients alive has resulted in an increased incidence of complications in this population. The pathophysiology of trauma complications is tremendously complex. Biomarkers have traditionally been considered as important area of medical research: the measurement of certain biomarkers has led to a better understanding of pathophysiology, while others have been used either to assess the effectiveness of specific treatments or for prognostic purposes. If with early diagnosis and early intervention, trauma complications can be prevented and cured. The aim of the review is to discuss new biomarkers which can be used in the prediction of severe trauma complications, mainly sepsis and Multiple Organ Dysfunction Syndrome (MODS). We also discuss to which degree currently available trauma complications biomarkers may help to overcome the present diagnostic uncertainty. We address how new insights into the pathogenesis of trauma complications may help in the development of specific biomarkers and how this may also impact the identification and development of new therapeutic targets. Research into biomarkers may help to predict the prognosis of patients with severe trauma.
Abstract: Trauma and its severe complications are major health problems and leading causes of mortality and morbidity among young people in the world. The increasing ability to keep most trauma patients alive has resulted in an increased incidence of complications in this population. The pathophysiology of trauma complications is tremendously complex. Biomar...
Show More
