Research Article
Super-Resolution Ultrasound Imaging of Oligodendroglioma: A Case Report and Literature Review
Issue:
Volume 13, Issue 5, October 2025
Pages:
120-125
Received:
28 June 2025
Accepted:
25 August 2025
Published:
5 September 2025
Abstract: Oligodendroglioma is a type of diffusely infiltrating glioma, most common in adults between 25 and 45 years old. Neuroimaging constitutes an essential component of both diagnostic evaluation and surgical planning. While conventional imaging modalities effectively delineate tumor location and extent, they possess inherent limitations in detecting early pathological changes. Ultrasound imaging enjoys widespread clinical adoption owing to its excellent tissue penetration, lack of ionizing radiation, real-time imaging capacity, and equipment portability. Intraoperative ultrasound tools like contrast-enhanced ultrasound (CEUS) have become crucial for real-time tumor mapping. CEUS uses microbubble contrast agents to enhance tumor visualization by highlighting perfusion differences, improving boundary definition and residual tumor detection. Super-resolution ultrasound (SR-US) has emerged as an innovative imaging modality capable of high-resolution vascular mapping and functional assessment. Given these capabilities, this article presents a CEUS-guided surgical case, demonstrating its role in optimizing tumor resection while preserving brain function. A 33-year-old female patient was admitted to the hospital with a three-day history of an intracranial mass detected during a routine physical examination. MRI revealed a cysto-solid mass in the right frontal lobe, suggesting oligodendroglioma. The patient underwent a right frontal lobe resection, during which intraoperative ultrasound, CEUS, and SR-US imaging were performed. These imaging techniques revealed a cysto-solid mass with no blood vessels within the tumor and a rich microvascular structure in the surrounding brain tissue. The tumor was resected, and pathological examination confirmed the diagnosis of oligodendroglioma (WHO Grade II). MRI is the preferred diagnostic method, while CEUS and SR-US imaging have significant value in the diagnosis and treatment of brain tumors, improving diagnostic accuracy and surgical resection rates.
Abstract: Oligodendroglioma is a type of diffusely infiltrating glioma, most common in adults between 25 and 45 years old. Neuroimaging constitutes an essential component of both diagnostic evaluation and surgical planning. While conventional imaging modalities effectively delineate tumor location and extent, they possess inherent limitations in detecting ea...
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Research Article
Role of Preoperative Localization Before Focused Parathyroidectomy in Case of Parathyroid Adenoma
Issue:
Volume 13, Issue 5, October 2025
Pages:
126-133
Received:
20 August 2025
Accepted:
3 September 2025
Published:
25 September 2025
Abstract: Background: Commonly, primary hyperparathyroidism is caused by a single parathyroid adenoma; a smaller fraction are hyperplasia, or multigland disease. Prelocalization of the diseased parathyroid gland is key to effective parathyroidectomy. Focused parathyroidectomy has become the standard treatment for selected patients with primary hyperparathyroidism. The aim is to assess the role of preoperative localization before doing focused parathyroidectomy. Methods: From July 2022 to June 2023, this cross-sectional study was conducted at Bangabandhu Sheikh Mujib Medical University's general surgery department in Dhaka. 14 patients with primary hyperparathyroidism had focused parathyroidectomy. Statistical analysis of the results was obtained by using window-based computer software with IBM SPSS statistics (Version 22). Results: The male-to-female ratio was 2.5:1, and the mean age was 32.36 years (SD = 9.76). The sensitivity, specificity, and accuracy for the ultrasound’s validity test were 75.0%, 50.0%, and 71.4%, respectively. The validity test for the Sestamibi scan has an accuracy of 85.7%, a specificity of 0.0%, and a sensitivity of 100.0%. The biochemical frozen section validity test's sensitivity, specificity, accuracy, and positive and negative predictive values were all 100%. The majority of individuals (85.7%) in the histopathology study investigation had parathyroid adenoma. The range of the postoperative hospital stay was 2 to 19 days, with an average of 8.2±6.26 days. Not all patients who underwent surgery had ugly scars. Conclusion: Preoperative localization enables patients to have focused parathyroidectomy, which is potentially cost effective, reduce postoperative complication, hospital stay with good cosmesis and patient satisfaction; ultimately improve postoperative outcome.
Abstract: Background: Commonly, primary hyperparathyroidism is caused by a single parathyroid adenoma; a smaller fraction are hyperplasia, or multigland disease. Prelocalization of the diseased parathyroid gland is key to effective parathyroidectomy. Focused parathyroidectomy has become the standard treatment for selected patients with primary hyperparathyro...
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Review Article
Gastrointestinal Stromal Tumour Management at the Bouake University Hospital
Issue:
Volume 13, Issue 5, October 2025
Pages:
134-140
Received:
20 August 2025
Accepted:
3 September 2025
Published:
25 September 2025
Abstract: Gastric GISTs are rare tumours that are often detected late. The aim of this study was to describe the different treatment modalities for gastric GISTs at Bouake University Hospital. It was retrospective study of 17 patients with gastric GIST between January 2013 and December 2023. GISTs accounted for 4.2% of all gastric tumours. The main reason for consultation was an abdominal mass. The average duration of progression was 10.9 months ± 2.1 months. FOGD, performed in 7 patients, suspected GIST in only one case. Abdominal CT scan, performed in 15 patients, was suggestive of GIST in 8 cases. The tumour was located in the antrum in 11 cases. There was extension to neighbouring organs in 5 cases. The tumours were classified as stage III in 9 cases. Immunohistochemistry confirmed the diagnosis of GIST with expression of C-KIT (CD117) antibodies in all cases. GIST is most often diagnosed at the stage of a large abdominal mass. Immunohistochemistry, which allows for diagnostic confirmation, is not accessible to most patients.
Abstract: Gastric GISTs are rare tumours that are often detected late. The aim of this study was to describe the different treatment modalities for gastric GISTs at Bouake University Hospital. It was retrospective study of 17 patients with gastric GIST between January 2013 and December 2023. GISTs accounted for 4.2% of all gastric tumours. The main reason fo...
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,
Xue Song
