Assessment of the Content of Dietary Trans Fatty Acids and Biologically Active Substances in Cow's Milk and Curd
Silviya Ivanova,
Ljubomir Angelov
Issue:
Volume 5, Issue 6, December 2017
Pages:
86-92
Received:
26 September 2017
Accepted:
14 October 2017
Published:
8 November 2017
Abstract: The present study aims to establish the content of natural trans fatty acids (TFA), biologically active and anticancerogenic components in cow's milk, obtained from the Bulgarian Rhodope Cattle breed and the curd produced by it during the lactation, and to evaluate the fatty acid composition of milk fat as a healthy source of human nutrition. The insurance of livestock with nutritional resource rich of linoleic and alpha linolenic acid on pasture grass rearing cows leads to an increase the quality in the fat fraction of milk in terms of biologically active fatty acids- omega-3, omega-6, CLA, trans and cis-fatty acids and decreases the amount of saturated fatty acids. The production of curd does not lead to substantial changes in the fatty acid composition resulting from well-conducted and respected technological processing. The assessment of the lipid preventive score, atherogenic and thrombogenic index in the milk and the curds produced by it give us an idea of the usefulness of the given product- high lipid preventive score and atherogenic index (over 1.0) and low cholesterolemic index (less than 1.0). The studied cow’s milk are characterized by product as low content of trans fatty acids (from 0.11 to 0.21 g / 100 ml product) and high amount of saturated fatty acids, the results obtained of curd are similarly- product with low content of trans fatty acids (0.34 to 1.09 g/100g product) and a high amount of saturated fatty acid content (from 12.63 to 19.96 g/100g product).
Abstract: The present study aims to establish the content of natural trans fatty acids (TFA), biologically active and anticancerogenic components in cow's milk, obtained from the Bulgarian Rhodope Cattle breed and the curd produced by it during the lactation, and to evaluate the fatty acid composition of milk fat as a healthy source of human nutrition. The i...
Show More
Sensitive Extractional Colorimetric Analysis of Fexofenadine Hydrochloride and Irbesartan Bases Through Acid-Dye Complexation Using Naphthol Blue Black in Pure Form and Pharmaceuticals
Safwan Ashour,
Roula Bayram
Issue:
Volume 5, Issue 6, December 2017
Pages:
93-100
Received:
25 January 2017
Accepted:
10 February 2017
Published:
28 November 2017
Abstract: A simple, accurate and sensitive method has been presented for the determination of fexofenadine hydrochloride (FEX) and irbesartan (IRB) in bulk and pharmaceutical preparations. The method is based on the reaction of the above cited drugs with naphthol blue black (NBB) dye in solutions containing Britton buffer to form ion-pair complexes extractable with chloroform and subsequently measured spectrophotometrically at 625 nm. All the reaction conditions for the proposed methods have been studied. The reactions were extremely rapid at room temperature and the absorbance values remained unchanged for at least 24 hrs. Beer's law was obeyed in the concentration ranges 2.7–53.8 and 10–244 μg mL-1 with detection limit of 0.013 and 0.75 μg mL-1 for FEX and IRB, respectively. The proposed methods were applied successfully for the determination of FEX and IRB in pharmaceutical formulations. Interferences of the other ingredients and excipients were not observed. The results obtained were compared statistically with those obtained by the official method and showed no significant differences regarding accuracy and precision.
Abstract: A simple, accurate and sensitive method has been presented for the determination of fexofenadine hydrochloride (FEX) and irbesartan (IRB) in bulk and pharmaceutical preparations. The method is based on the reaction of the above cited drugs with naphthol blue black (NBB) dye in solutions containing Britton buffer to form ion-pair complexes extractab...
Show More
Barium Diphenylamine-4-Sulfonate (BDPA) Ion-Ion Interactions and Solvation Volumes in Acetonitrile–Water Mixed Solvents
Elsayed T. Helmy,
Esam A. Gomaa,
Elsayed M. Abou Eleef
Issue:
Volume 5, Issue 6, December 2017
Pages:
101-105
Received:
7 November 2017
Accepted:
20 November 2017
Published:
2 January 2018
Abstract: The aim of this work is to calculate ion-ion interaction, density of organic-aqueous mixtures of Acetonitrile-water (AN-H2O), density of saturated solutions of BDPA, salvation volumes (Van der Waals volume VM, molar volume VM and electrostriction volume Ve) and solvated radii (ro) from solubility experiments. It was found that values of the log activity coefficient (γ+) of BDPA in (AN-H2O) mixture were decreases by increasing in the content of the organic solvent used. The values of the log γ+ found to decrease with the increase in temperature. The densities and the molar volumes of the saturated solutions of BDPA decrease by increasing ratio of AN and also increases by increasing in temperature. All the electrostriction volumes calculated for BDPA having negative values. The electrostriction volumes increase in negativity on increasing the percentages of the organic solvent. The solvated radii of BDPA are increased as the organic solvent content increase and as the temperature increase.
Abstract: The aim of this work is to calculate ion-ion interaction, density of organic-aqueous mixtures of Acetonitrile-water (AN-H2O), density of saturated solutions of BDPA, salvation volumes (Van der Waals volume VM, molar volume VM and electrostriction volume Ve) and solvated radii (ro) from solubility experiments. It was found that values of the log act...
Show More
