Enamines in Heterocyclic Synthesis: Route to Aminopyrazolopyrimidines and Arylpyrazolopyrimidiens Derivatives
Hanadi Yousef. Medrasi,
Abdellatif Mohamed Salaheldin
Issue:
Volume 2, Issue 1, February 2014
Pages:
1-5
Received:
20 February 2014
Published:
30 March 2014
Abstract: An easy preparation of enaminonitrile derivatives, obtained by using a mixture of triethyl orthoformate and piperidine in DMF solution, and their transformation into new substituted azolopyrimidines is described. The one-step transformation was carried out under microwave irradiation and by classical heating methods. The use of microwave irradiation led to high conversion and shorter reaction times.
Abstract: An easy preparation of enaminonitrile derivatives, obtained by using a mixture of triethyl orthoformate and piperidine in DMF solution, and their transformation into new substituted azolopyrimidines is described. The one-step transformation was carried out under microwave irradiation and by classical heating methods. The use of microwave irradiatio...
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