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An Analysis of Severe Coal Mine Trauma Curing According to 144 Examples
Sun Bingfeng,
Fan Shifeng,
Fu Qiang,
Gao Yuan,
Wang Wei,
Ye Chunyong,
Hu Guolun,
Wang Xinpan,
Chen Hongyan
Issue:
Volume 5, Issue 3, June 2019
Pages:
43-45
Received:
3 June 2019
Accepted:
11 July 2019
Published:
23 July 2019
Abstract: Introduction: improve the level of curing severe coal mine trauma patients, find out the regulations and deficiencies of coal mine severe trauma treatment Method: summarize and analyze 144 case data of severe coal mine trauma patients from 5 hospitals in Liupanshui City from March 2014 to March 2017 Result: 144 severe coal mine trauma patients are all males and their average age is 40.92 years old. Most of them hospitalize in the ICU (admission from April to June, about 29.17%) while fewest of them (admission from July to September, about 17.26%). Most patients hospitalize in the ICU about 0.85 days after the severe coal mine trauma happens and the average treatment time of ICU is 15.15 days. Patient source comes most from the people of emergency (94.44%), fewest from the people who transferred after experienced treatment in other hospital. The average score of SOFA evaluation is 4.1 while the average score in APACHE II evaluation is 16.2. Most kind of work which trauma takes place easily is coal mining (74.31%); other jobs which trauma also happens are driving (7.64%), ventilation (8.33%), transportation (6.94%), electromechanics (1.39%). The main reason of trauma is roof failure (41.67%), and there’re other reasons like harvesters extrusion (36.11%), falling (7.64%), electromechanics explosion (7.64%), high gas (5.56%). The main hurt organs are craniocerebal, lung, abdomen, limbs, centrum, maxillofacial. The implementation rate of tertiary rescue is 79.86%. Finally, 135 people survive after treatment while 9 people die. Conclusion: The treatment of severe coal mine trauma has its own regulation and characteristic, attaching high importance to the coal mine security, tertiary rescue and trauma curing is benefit to improve the success rate of curing severe coal mine trauma.
Abstract: Introduction: improve the level of curing severe coal mine trauma patients, find out the regulations and deficiencies of coal mine severe trauma treatment Method: summarize and analyze 144 case data of severe coal mine trauma patients from 5 hospitals in Liupanshui City from March 2014 to March 2017 Result: 144 severe coal mine trauma patients are ...
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Digital Profile of Klebsiella Pneumoniae Strains Producing Extended Spectrum β-Lactamase Isolated in Hospitals in the Littoral Region of Cameroon
Jean Teghonong,
Cecile Okalla Ebongue,
Callixte Yadufashije,
Dieudonne Adiogo
Issue:
Volume 5, Issue 3, June 2019
Pages:
46-50
Received:
24 May 2019
Accepted:
1 July 2019
Published:
24 July 2019
Abstract: Miniaturized galleries are essential for a good identification of bacteria. The aim of this study was to identify multi-resistant Klebsiellap neumoniae strains in the referral health structures of Cameroon littoral region and establish a digital profile. A cross-sectional and descriptivestudy was conducted during 2016 and early 2017, intermediate susceptibility isolates or resistant to cephalosporins third generation (C3G) were collected in the laboratories of referral hospitals of the Littoral (General Hospital, Laquintinie, Military, Gyneco-obstetrics and pediatrics of Douala and Saint John of Malta of Njombé) and in Diagmed laboratory. The confirmation of the strains was made by the gallery API 20E™ (BioMérieux). In this study, atotal of 412 strains of Klebsiellasp (species) were isolated. We obtained 125 strains of Klebsiellasp intermediate or resistant to (C3G) and 122 were confirmed to be Klebsiella pneumoniae. The sex ratio (F / M) was 1.26. Klebsiella pneumoniae pneumonia was the species mostly identified at 82.4% and the two digital profiles mainly found were 5215773 and 1215773 with respective frequencies of 52.8% and 18.4%. The biochemical profile: LDC (+), CIT (+), URE (+), IND (-), VP (+), GLU (+), MAN (+), INO (+), SOR (+), RHA (+), SAC (+), MEL (+), ARA (+) was found in all services. There is a high frequency of Klebsiella pneumoniae pneumonia with several different digital profiles, so it is still essential to make a good identification to facilitate the epidemiological data.
Abstract: Miniaturized galleries are essential for a good identification of bacteria. The aim of this study was to identify multi-resistant Klebsiellap neumoniae strains in the referral health structures of Cameroon littoral region and establish a digital profile. A cross-sectional and descriptivestudy was conducted during 2016 and early 2017, intermediate s...
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Ribavirin Concentrations, Laboratory Variables, and Clinical Outcomes During Treatment of Hepatitis C Infection with First Generation Direct-Acting Antivirals
Halina Michur,
Phillip Morgan,
Ivana Carey,
Nigel Brown,
Nigel Heaton,
Michael Heneghan,
Kosh Agarwal,
John Michael Tredger
Issue:
Volume 5, Issue 3, June 2019
Pages:
51-57
Received:
12 July 2019
Accepted:
20 August 2019
Published:
9 September 2019
Abstract: In treating hepatitis C infection, identification of reliable markers predicting virological non-response appear central to improving outcome and to prompting changes in dynamic treatment approaches. The interrelationship of ribavirin (RBV) concentrations and laboratory variables with clinical outcomes was evaluated in HCV patients treated with ribavirin, and with or without early direct acting antivirals (DAA). Correlations between RBV concentration, laboratory variables (haemoglobin, absolute lymphocyte, platelet and neutrophil counts, serum creatinine and hepatitis C viral load) and patients’ characteristics associated with sustained virological response (SVR) were investigated using multivariate analysis. The 76 patients studied all received interferon (INF) and RBV, with 37 additionally given Boceprevir or Telaprevir. Significant correlations were noted between week 1 RBV concentration and subsequent total exposure at weeks 2, 4 and 12 (P < 0.0001). RBV concentrations in excess of 1.0 mg/L (week 1) and 2.0 mg/L (week 2) provided targets for avoiding breakthrough (P < 0.05). SVR was greater in patients without cirrhosis (73.3% vs. 41.3%; P < 0.01). All patients with an absolute haemoglobin (Hb) fall >30 g/L (week 8) experienced higher SVR rates (P < 0.03). RBV concentrations above 2.7 mg/L at week 4 or later increased the likelihood of Hb falls >30 g/L. Six factors were predictive of SVR in univariate analysis, and three in multivariate analysis. There is an association between SVR and absolute lymphocyte count, IL-28B CC genotype, and HCV-RNA load fall at week 1 (>80 %) or week 2 (>90 %) in HCV patients treated with INF/RBV and early DAA.
Abstract: In treating hepatitis C infection, identification of reliable markers predicting virological non-response appear central to improving outcome and to prompting changes in dynamic treatment approaches. The interrelationship of ribavirin (RBV) concentrations and laboratory variables with clinical outcomes was evaluated in HCV patients treated with rib...
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