-
Synthesis and Characterization of Some Metal Complexes of Cu(II), Ni(II), Zn(II), Cd(II), Sn(II), Co(II), Sb(III) AND Fe(III) Containing Bidentate Schiff Base of Smdtc
Abdul Alim,
Md. Kudrat-E-Zahan,
Md. Masuqul Haque,
MTH Tarafder
Issue:
Volume 3, Issue 3, June 2015
Pages:
35-39
Received:
20 March 2015
Accepted:
29 March 2015
Published:
21 April 2015
Abstract: A series of transition metal complexes of Cu(II), Ni(III) Zn(II), Cd(II), Co(II), Sb(III) and Fe(III)Containing Bidentate Schiff base, [NI-(4-chloro-benzylidene)-hydrazecarbodithioicacid methyl ester] derived from the condensation of S- methyldithiocarbazate and P-chlorobenzaldehyde were synthesized and characterized by IR, UV- Vis., and some physical measurements. IR spectral studies show the binding sites of the Schiff base ligand with the metal ion. Molar conductance data and magnetic susceptibility measurements give evidence for monomeric and neutral nature of the complexes.
Abstract: A series of transition metal complexes of Cu(II), Ni(III) Zn(II), Cd(II), Co(II), Sb(III) and Fe(III)Containing Bidentate Schiff base, [NI-(4-chloro-benzylidene)-hydrazecarbodithioicacid methyl ester] derived from the condensation of S- methyldithiocarbazate and P-chlorobenzaldehyde were synthesized and characterized by IR, UV- Vis., and some phys...
Show More
-
Comparative Chemical Constituents of some Cassia Species and their Pharmacognistic Importance in South Eastern Nigeria
Awomukwu,
Daniel Azubuike,
Nyananyo,
Bio Louis,
Ikpeama,
Ahamefule Ifeanyichukwu,
Adieze,
Charles Ugochukwu
Issue:
Volume 3, Issue 3, June 2015
Pages:
40-49
Received:
6 April 2015
Accepted:
25 April 2015
Published:
11 May 2015
Abstract: An assessment and investigation into three species of Cassia namely Cassia alata Linn., Cassia occidentalis Linn. and Cassia sieberiana DC. belonging to the family of Fabaceae (subfamily Caesalpinoideae) was carried out with the aim of identifying and quantifying the bioactive components of these ornamental shrubs. The alkaloid, flavonoid, saponin, steroid, phenol and tannin contents of the vegetative and reproductive parts of these plants viz. the leaves, stems, roots and pods were screened and compared. All the plant parts investigated contained appreciable amount of alkaloids, flavonoids and saponins ranging from (1.24 ± 0.06% - 4.06 ± 0.51%), (1.18 ± 0.0% - 2.68 ± 0%) and (2.20 ± 0.03% - 4.28 ± 0%) respectively. Tannin contents on the plant parts were equally high (1.12 ± 0.01% - 1.54 ± 0.01%), while the phenol contents ranged from (0.13 ± 0% - 0.36 ± 0%) respectively. These analytical results suggest the plants have a significant role in phyto-medicine. The importance of these plants was discussed in line with the role they play in ethno-medicinal life of the people.
Abstract: An assessment and investigation into three species of Cassia namely Cassia alata Linn., Cassia occidentalis Linn. and Cassia sieberiana DC. belonging to the family of Fabaceae (subfamily Caesalpinoideae) was carried out with the aim of identifying and quantifying the bioactive components of these ornamental shrubs. The alkaloid, flavonoid, saponin,...
Show More
-
Synthesis of New Curcumin Analogues from Kulit Lawang Oils Using the Conventional Method and Microwave
Imanuel Berly Delvis Kapelle,
Tun Tedja Irawadi,
Meika Syahbana Rusli,
Djumali Mangunwidjaja,
Zainal Alim Mas’ud
Issue:
Volume 3, Issue 3, June 2015
Pages:
50-56
Received:
17 April 2015
Accepted:
29 April 2015
Published:
12 May 2015
Abstract: Kulit lawang oils are essential oils that are widely available in the Moluccas and oil major component contain eugenol and safrole. Safrole can be converted into value-added products that curcumin analogues. The purpose of this research is to synthesize new compounds curcumin analogues from kulit lawang oils. The steps being taken is isolation safrole, safrole isomerization and oxidation isosafrole produce piperonal. The method synthesis curcumin analogues with piperonal precursor with two methods: conventional and microwave. Results safrole isolation from skin oils mace using alkaline extraction method for 5 hours yield 19.30% were is characterized by GCMS, FTIR and 1H-NMR. Isosafrole proceeds reaction isomerization safrole without the use of solvents for 6 hours at a temperature of 120 ° C obtained yield 77.56% with two products cis-isosafrole (15.4%) and trans-isosafrole (69.34%) were characterized by GC, FTIR and 1H-NMR. Precursors piperonal which was resulting obtained from the oxidation reaction isosafrol using KMnO4 at temperature < 30 °C obtained yield 65.63% were characterized by GCMS, FTIR and 1H-NMR. Results synthesis curcumin analogues (1,5-Bis-benzo [1,3] dioxol-5-yl-penta-1,4-dien-3-one) in the conventional method using 10% NaOH catalyst for 3 hours at a temperature of 25 °C be obtained yield 78.43% and synthesized using microwave at 140 watts for 2 minutes obtained yield 53.3%.
Abstract: Kulit lawang oils are essential oils that are widely available in the Moluccas and oil major component contain eugenol and safrole. Safrole can be converted into value-added products that curcumin analogues. The purpose of this research is to synthesize new compounds curcumin analogues from kulit lawang oils. The steps being taken is isolation safr...
Show More
-
Nucleophilic Displacements at Carbonyl Compounds
Issue:
Volume 3, Issue 3, June 2015
Pages:
57-61
Received:
23 April 2015
Accepted:
17 May 2015
Published:
27 May 2015
Abstract: The nucleophilic displacements at carbonyl center are remarkable. Mainly stepwise mechanism was found in these reactions. The stepwise mechanism with rate-limiting addition of the nucleophilie to the carbonyl group to form zwitterionic tetrahedral intermediate was a common type of mechanism. Such as, Dey et al. [1] proposed the pyridinolyses of α-chloroacetanilides proceed via a stepwise mechanism with rate-limiting addition of the nucleophile to the carbonyl group to form zwitterionic tetrahedral intermediate (T±). In some cases concerted mechanism was found. Oh and coworkers [9] reported that a concerted mechanism with a hydrogen bonded cyclic transition state for the aminolysis of aryl N-allyl thiocarbamates with benzylamines in acetonitrile The mechanism change from stepwise to concerted was also found in some cases. It was concluded that the change of the amine from benzylamines to anilines causes a shift of the aminolysis mechanism from a concerted to a stepwise process. This paper includes an exclusive review of literature from 1997 to 2015.
Abstract: The nucleophilic displacements at carbonyl center are remarkable. Mainly stepwise mechanism was found in these reactions. The stepwise mechanism with rate-limiting addition of the nucleophilie to the carbonyl group to form zwitterionic tetrahedral intermediate was a common type of mechanism. Such as, Dey et al. [1] proposed the pyridinolyses of α-c...
Show More
-
Synthesis of Myristicin Ketone (3,4-Methylenedioxy-5-Methoxyphenyl)-2-Propanone from Myristicin
Hanoch Julianus Sohilait,
Healthy Kainama
Issue:
Volume 3, Issue 3, June 2015
Pages:
62-66
Received:
12 May 2015
Accepted:
29 May 2015
Published:
11 June 2015
Abstract: The synthesis of myristicin ketone from myristicin has been achieved through conversion of allyl group to ketone. Myristicin was isolated from nutmeg oil. The reaction of myristicin with mercury acetate in aqueous tetrahydrofuran, followed by in situ reduction of the mercurial intermediate by alkaline solution sodium borohydride produced myristicin alcohol. Myristicin alcohol was oxidized with PCC at 40 0C for 90 minutes, followed by purified with saturated potassium disulphite yield myristicin ketone (3-methoxy-4,5-methylenedioxyphenyl)-2-propanone (68.32%).
Abstract: The synthesis of myristicin ketone from myristicin has been achieved through conversion of allyl group to ketone. Myristicin was isolated from nutmeg oil. The reaction of myristicin with mercury acetate in aqueous tetrahydrofuran, followed by in situ reduction of the mercurial intermediate by alkaline solution sodium borohydride produced myristicin...
Show More
