Abstract: Modulation is a process through which a message has to pass in order to be effectively transmitted. However, there are some limitations to Pulse Code Modulation and Delta Modulation that can cause data redundancy, quantization error, slope overload distortion and granular noise which result in a bad communication process. Throughout the past few years, Pulse Code Modulation (PCM), Delta Modulation (DM) and Differential Pulse Code Modulation (DPCM), in digital communication systems, have proven to have unparalleled advantages over analog communication systems; this is in terms of error minimization and distances of transmission enhancements. Delta Modulation, a simplified version of Pulse Coded Modulation also pauses major problems in noise and quantization error. Consequently, and to combat the arising problems, communication engineers have developed newly adaptive compression and modulations techniques for better digital transmission. One of these innovative systems is the Differential Pulse Coded Modulation (DPCM) that can solve the aforementioned problems. Thus the focal point of this article is to explore the simulation of these systems using Simulink (The Math Works, Inc., USA). Eventually, the systems are tested on both image and audio inputs to prove the superiority of DPCM over DM and PCM systems in reducing noise and increasing the signal to quantization noise ratio, thus insuring a smooth and successful transfer of data.Abstract: Modulation is a process through which a message has to pass in order to be effectively transmitted. However, there are some limitations to Pulse Code Modulation and Delta Modulation that can cause data redundancy, quantization error, slope overload distortion and granular noise which result in a bad communication process. Throughout the past few ye...Show More