Abstract: Multiple myeloma is a malignant, hematological neoplasia affected plasma cells. It causes anemia, leads to increased susceptibility to infections by compromising immune response and severe pain is raised as a result of osteolytic lesions. For medical therapy of this condition, bisphosphonates (BPs) can be prescribed. Despite its great benefits in Multiple Myeloma (MM), in particular intravenous administration of BPs can lead to Medication-related osteonecrosis of the jaws (MRONJ). A 61-year-old female patient refers to our department for complaint of difficulty on usage of her prosthesis. In medical history, it was learned that her chemotherapy for multiple myeloma has been continued for 5 years and skull radiographs showed characteristic punched-out lytic lesions. With clinical and radiological examinations, this condition diagnosed as Stage II MRONJ. The aim of this study is to report the case of MRONJ within the reason of incompatible prosthesis by this way to be directive about preventive management.Abstract: Multiple myeloma is a malignant, hematological neoplasia affected plasma cells. It causes anemia, leads to increased susceptibility to infections by compromising immune response and severe pain is raised as a result of osteolytic lesions. For medical therapy of this condition, bisphosphonates (BPs) can be prescribed. Despite its great benefits in M...Show More
Abstract: The aim of this article is to describe the treatment of a skeletal Class III and asymmetric patient. Two treatment alternatives were explained: -conventional orthodontics to camouflage the skeletal anomaly and -traditional orthodontics/orthognathic surgery approach; the surgical option was selected. Pre-surgical orthodontics was applied for leveling, aligning and relieving dental compensations. A Bilateral Sagital Split Osteotomy was performed for mandibular setback. Post-surgical orthodontics was applied for finishing and detailing occlusion. Total treatment time was 10 months. Facial balance was enhanced and a good dental occlusion was achieved. Careful treatment planning by the ortho-surgical team, proper application of biomechanics and good selection of dental orthodontic materials, allow the orthodontist to delay less time in the pre and post-surgical stages in the traditional surgical orthodontic approach.Abstract: The aim of this article is to describe the treatment of a skeletal Class III and asymmetric patient. Two treatment alternatives were explained: -conventional orthodontics to camouflage the skeletal anomaly and -traditional orthodontics/orthognathic surgery approach; the surgical option was selected. Pre-surgical orthodontics was applied for levelin...Show More