Effects of Moringa oleifera Biochemical Constituents on Kidney, Liver and Brain of Wister Rats
Ibrahim Maina Hassan,
Bashir Saidu,
Ja’afaru Abdullahi Ishaq,
Ashiru Dahiru,
Nafisat Abdulazeez,
Halima Ibrahim Yusuf,
Dahiru Hafiz Karofi,
Nicholas Nathaniel Pilau,
Adamu Abdul Abubakar,
Bulama Ibrahim,
Adama Musa Abdullahi
Issue:
Volume 8, Issue 4, December 2020
Pages:
128-132
Received:
18 March 2020
Accepted:
2 April 2020
Published:
31 December 2020
Abstract: Medicinal plant have evolved over the centuries as essential parts of African civilization and are widely recognized today as representing its rich cultural and scientific heritage. The increasing demand for Medicinal plant products has renewed interest in the pharmaceutical industry in the production of herbal health care formulations, herbal-based cosmetic products, and herbal nutritional supplements. Thus, in addition to serving medical and cultural functions, Medicinal plants in Africa have economic importance. Global and national markets have been growing for medicinal herbs, and significant economic gains are being realized through the sale of medicinal plant products. The aim of this particular investigation was to observe the effects of Moringa oleifera 80% methanol leaf extract on the histological architecture of kidney, liver and brain tissues. Fifteen (15) rats were randomLy divided into three (3) with five rats per group. Rats were exposed to 2000 mg/kg, 1000 mg/kg and 500 mg/kg of Moringa oleifera extract per os (p.o) along with the control group that was placed on commercial diet. There was no observed mortality in all experimental rats but there is deleterious effect in brain, liver and kidney in those that were exposed to higher doses especially the 2000 mg/kg. It’s therefore concluded that higher dose of Moringa oleifera is toxic while moderate doses is safe to most vital organs especially brain, liver and kidney. There is need for further investigation to identify the phytochemical constituents that are responsible for the toxic effects.
Abstract: Medicinal plant have evolved over the centuries as essential parts of African civilization and are widely recognized today as representing its rich cultural and scientific heritage. The increasing demand for Medicinal plant products has renewed interest in the pharmaceutical industry in the production of herbal health care formulations, herbal-base...
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Comparative Assessment of Physico-chemical Characteristics of Two Grassland Soils Subjected to Different Uses in Delta State, Nigeria
Amukali Ogochukwu,
Obadoni Bernard Onyemaechi,
Bariweni Perekibina Anthony,
Iwuegbu Elizabeth
Issue:
Volume 8, Issue 4, December 2020
Pages:
133-137
Received:
26 May 2020
Accepted:
18 June 2020
Published:
31 December 2020
Abstract: In this study, physico-chemical properties of 2 differentially located grassland soils which were subjected to different economic usages, were assessed. The study was carried out for grassland soils of Ogbole-Ogume (excavation) and Abbi (Cultivation), both in Ndokwa West LGA of Delta State, Nigeria. The soils were collected at the road margin (0m), 30m into the grasslands and 10m away from the end of the grasslands at a depth of about 10.30m each from the soil surfaces. Soil characteristics as pH, Mg, Ca, Na, K, EC, CEC, SO₄, P, N, clay, silt and sand contents were analyzed following standard procedures and methodologies. At margins, soils from Ogbole-Ogume and Abbi contained 94.5% and 91.0% sand; at 30m into the grasslands, both were 93.0% sand while at 10m beyond the grassland soils, 93.0% and 90.0% sand were recorded for Ogbole-Ogume and Abbi, respectively. Comparatively, physico-chemical parameters investigated in this study showed variations between both sampled sites as parameters like pH, Mg, Ca, K, CEC, P and N were generally higher in Abbi than in Ogbole-Ogume grassland soils. This clearly indicated that crop cultivation at Abbi grassland soils must have significantly impacted more on the physico-chemical properties of the soils than excavation activities as practiced at Ogbole-Ogume grassland soils. This has strong indications for food security and environmental health.
Abstract: In this study, physico-chemical properties of 2 differentially located grassland soils which were subjected to different economic usages, were assessed. The study was carried out for grassland soils of Ogbole-Ogume (excavation) and Abbi (Cultivation), both in Ndokwa West LGA of Delta State, Nigeria. The soils were collected at the road margin (0m),...
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