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Determination of Iron in Some Selected Iron Containing Tablets Using Redox Titration

Received: 31 August 2019     Accepted: 20 September 2019     Published: 30 September 2019
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Abstract

Iron is an essential trace element, required for haemoglobin formation and the oxidative process of living tissues. A comparative study of the determination of iron in iron tablets was carried out using Redox titration on five samples of capsule containing iron. The capsules were analyzed using Redox titration on five of the samples containing iron content inform of ferrous fumarate. The weight of ferrous fumarate Fe (C4H2O4) as well as elemental Fe2+ in milligram per gram for each capsule containing ferrous fumarate was determined. The titration was carried out using potassium permanganate (vii) (KMNO4) which is the oxidation agent. The results obtained indicated Chemiron contained 144±4.61 (mg/g) while the label contained 150mg/g, Astyfer contained 74.6±5.69 (mg/g) while the label contained 80mg/g, Ferrobin plus contained 246±2.36 (mg/g) while the label contain 300mg/g, Emivite super contain 102±3.64 (mg/g) while the label contain 100mg/g, and Maxiron 265±1.73 (mg/g) while the label contain 250mg/g. Base on the results for the analysis of all the sample it can be concluded that Maxiron have the highest percentage of iron which is best supplements for adult lacking high percentage of iron. However, Astyfer has the lowest amount of iron which is the best supplement for infants who require very low amount of iron supplements.

Published in World Journal of Applied Chemistry (Volume 4, Issue 3)
DOI 10.11648/j.wjac.20190403.13
Page(s) 42-44
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Iron, Tablet, Redox, Supplement

References
[1] Rajbhandari, A., Aryal A. and Rajbhandari, S. D. “Determination of Iron in Iron Tablets by Spectrophotometry and Atomic Absorption Spectroscopy” International Journal of Pharmaceutical & Biological Archives 2013; 4 (3): 435-438 ISSN 0976-3333.
[2] Helen, A. C. (2006). “Introductory Nutrition” Thersmumir Mosby College. 4th edition, pp. 270.
[3] Kaur, S. “Iron Deficiency Anemia (IDA): A Review International Journal of Science and Research” (IJSR) Volume 5 Issue 4, April 2016 pages 1999-20003 ISSN (Online): 2319-7064.
[4] Gioia, A. M., Pietra, D. and Gatti, R. “Spectrophotometric Method of Determination of Iron” Journal ofPharmacuitical and Biomediacal Analysisvol. 29, no 6 (2002) 1159-1164 Doi: 10.1016/S0731-7085(02)00170-X.
[5] Garole, D. J. “Application of UV Spectrophotometric Methodfor Estimation of Iron in Tablet dosage form” International Journal of PharmTech Research, Vol. 4, No. 1, pp 309-310, Jan-Mar 2012 ISSN: 0974-4304.
[6] Brody, T. (1999) Nutritional Biochemistry. 2nd edition. San Diego: academic press; vol 3. Pp 345-349.
[7] Kennedy, A. (2014) “The Influence of Diet Prenatally and During the First Year of Life on Sour Taste Development a Longitudinal Investigation within an Irish Setting” 2014 (Doctoral dissertation, Dublin City University).
[8] Ibrahim, I. A. A. and Yusuf, A. J. “Quantitative Determination of Iron and Folic Acid in Lactucasativa (Lettuce) Plant” Adv. Appl. Sci. Res., 2015, 6 (7): 112-115 ISSN: 0976-8610.
[9] Yip, R. and Dallman, P. R. Iron, Present Knowledge in Nutrition, 7th edition, International Life Science Institute Press, Washington, DC 1996.
[10] World Health Organization (WHO). Iron Deficiency Anaemia Assessment, Prevention, and Control. A guide for programme manager. 2011.
[11] Adamson, J. W. Iron deficiency and other Hypoproliferative Anemias. In: Long DL, Kasper DL et al, editors. Harrison’s Principles of Internal Medicine. 18th ed. McGraw-Hill companies; 2012. p. 844-85.
[12] Habibzadeh, “Anemia in the Middle East” Lancet, vol. 379, no. 1, 2012.
[13] Bashanfer, S., Al-alim, A. A. and Morish, M. A. “Prevalence of Iron Deficiency Anemia among Univrsity Students in Hodeida Province Yemen” Anemia, vol. 2018, doi: 10.1155/2018/4157876.
[14] Habib, M. A., Black, K., Soofi, S. B., Hussain, I., Bhatti, Z., Bhutta, Z. A., et al. (2016) Prevalence and Predictors of Iron Deficiency Anemia in Children under Five Years of Age in Pakistan, A Secondary Analysis of National Nutrition Survey Data 2011–2012. PLoS ONE 11 (5): e0155051. doi: 10.1371/journal.pone.0155051.
[15] Miller, H. G. (1998). An Introduction to Tropical Food Science, Cambridge University press, New York. Pp. 297.
[16] Arthur, C. K., Isbister, J. P. and Schweter, H. P. “Iron deficiency: misunderstood, misdiagnosed and mistreated Drugs”. pp. 171-812.
[17] Agget, P. J (2012). Iron in present knowledge and nutrition (10th edition). Washington: Wiley-Blackwell. 506-518.
[18] Smith, H. J. and Hywel, (2007). Introduction to the Principle of Drug, John Wright and Son Ltd, London. Pp. 145-146.
[19] Chaka, G. T. (2010). “Determination of Iron in Dietary Supplements through Redox Titration” Collins College University, department of chemistry. Available online: www.collin.edu/chemistry/handout/1412/redoxtittrationexperiment.fpdf. Retrieved: 23/07/2016.
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  • APA Style

    Muhammad Auwal Balarabe, Aliyu Zainab Folashade. (2019). Determination of Iron in Some Selected Iron Containing Tablets Using Redox Titration. World Journal of Applied Chemistry, 4(3), 42-44. https://doi.org/10.11648/j.wjac.20190403.13

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    ACS Style

    Muhammad Auwal Balarabe; Aliyu Zainab Folashade. Determination of Iron in Some Selected Iron Containing Tablets Using Redox Titration. World J. Appl. Chem. 2019, 4(3), 42-44. doi: 10.11648/j.wjac.20190403.13

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    AMA Style

    Muhammad Auwal Balarabe, Aliyu Zainab Folashade. Determination of Iron in Some Selected Iron Containing Tablets Using Redox Titration. World J Appl Chem. 2019;4(3):42-44. doi: 10.11648/j.wjac.20190403.13

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  • @article{10.11648/j.wjac.20190403.13,
      author = {Muhammad Auwal Balarabe and Aliyu Zainab Folashade},
      title = {Determination of Iron in Some Selected Iron Containing Tablets Using Redox Titration},
      journal = {World Journal of Applied Chemistry},
      volume = {4},
      number = {3},
      pages = {42-44},
      doi = {10.11648/j.wjac.20190403.13},
      url = {https://doi.org/10.11648/j.wjac.20190403.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjac.20190403.13},
      abstract = {Iron is an essential trace element, required for haemoglobin formation and the oxidative process of living tissues. A comparative study of the determination of iron in iron tablets was carried out using Redox titration on five samples of capsule containing iron. The capsules were analyzed using Redox titration on five of the samples containing iron content inform of ferrous fumarate. The weight of ferrous fumarate Fe (C4H2O4) as well as elemental Fe2+ in milligram per gram for each capsule containing ferrous fumarate was determined. The titration was carried out using potassium permanganate (vii) (KMNO4) which is the oxidation agent. The results obtained indicated Chemiron contained 144±4.61 (mg/g) while the label contained 150mg/g, Astyfer contained 74.6±5.69 (mg/g) while the label contained 80mg/g, Ferrobin plus contained 246±2.36 (mg/g) while the label contain 300mg/g, Emivite super contain 102±3.64 (mg/g) while the label contain 100mg/g, and Maxiron 265±1.73 (mg/g) while the label contain 250mg/g. Base on the results for the analysis of all the sample it can be concluded that Maxiron have the highest percentage of iron which is best supplements for adult lacking high percentage of iron. However, Astyfer has the lowest amount of iron which is the best supplement for infants who require very low amount of iron supplements.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Determination of Iron in Some Selected Iron Containing Tablets Using Redox Titration
    AU  - Muhammad Auwal Balarabe
    AU  - Aliyu Zainab Folashade
    Y1  - 2019/09/30
    PY  - 2019
    N1  - https://doi.org/10.11648/j.wjac.20190403.13
    DO  - 10.11648/j.wjac.20190403.13
    T2  - World Journal of Applied Chemistry
    JF  - World Journal of Applied Chemistry
    JO  - World Journal of Applied Chemistry
    SP  - 42
    EP  - 44
    PB  - Science Publishing Group
    SN  - 2637-5982
    UR  - https://doi.org/10.11648/j.wjac.20190403.13
    AB  - Iron is an essential trace element, required for haemoglobin formation and the oxidative process of living tissues. A comparative study of the determination of iron in iron tablets was carried out using Redox titration on five samples of capsule containing iron. The capsules were analyzed using Redox titration on five of the samples containing iron content inform of ferrous fumarate. The weight of ferrous fumarate Fe (C4H2O4) as well as elemental Fe2+ in milligram per gram for each capsule containing ferrous fumarate was determined. The titration was carried out using potassium permanganate (vii) (KMNO4) which is the oxidation agent. The results obtained indicated Chemiron contained 144±4.61 (mg/g) while the label contained 150mg/g, Astyfer contained 74.6±5.69 (mg/g) while the label contained 80mg/g, Ferrobin plus contained 246±2.36 (mg/g) while the label contain 300mg/g, Emivite super contain 102±3.64 (mg/g) while the label contain 100mg/g, and Maxiron 265±1.73 (mg/g) while the label contain 250mg/g. Base on the results for the analysis of all the sample it can be concluded that Maxiron have the highest percentage of iron which is best supplements for adult lacking high percentage of iron. However, Astyfer has the lowest amount of iron which is the best supplement for infants who require very low amount of iron supplements.
    VL  - 4
    IS  - 3
    ER  - 

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Author Information
  • Department of Pure and Applied Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria

  • Department of Pure and Applied Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria

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