This study was conducted to investigate the antiemetic, antimicrobial and anti-radical activity of methanolic extracts of Foeniculum vulgare. The antiemetic assay was carried out by using chick emetic model with minor modifications by calculating the mean decrease in the number of retching. The antimicrobial activity of the crude extract was performed by Disc Diffusion method. The anti-radical activity was determined by the 2, 2-diphenyl-2-picrylhydrazyl hydrate (DPPH) method. The anti-emetic activity of Foeniculum vulgare leaves on young chicks revealed that these extracts have a less anti-emetic effect. The group of chicks treated with Chlorpromazine was found to have 60.6 retches as compared to the 66 retches of the control group, thus Chlorpromazine reduced the retches by 7.93%. The chickens treated with leaves extracts inhibited the retches up to 2.03%. The minimum antimicrobial effect was found in this methanol crude extract. The extract did not appear potent in terms of both zones of inhibition and spectrum of activity. In anti-radical activity test, the extract showed moderate free radical scavenging activity with IC50 value 240.39μg/ml. while compared to that of the reference standard ascorbic acid. Methanolic extract of Foeniculum vulgare leaves have minimum anti-emetic and anti-microbial activities and moderate anti-radical properties.
| Published in | Pharmaceutical Science and Technology (Volume 3, Issue 1) |
| DOI | 10.11648/j.pst.20190301.14 |
| Page(s) | 27-33 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Antiemetic, Antimicrobial, Antioxidant, Foeniculum vulgare
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APA Style
Md. Ruhul Amin, Md. Abdullah-Al-Masum, Asma Kabir, Tofazzal Hossain Rubel, Md. Omar Faruqe, et al. (2019). Pharmacological Study on a Potential Medicinal Herb-Foeniculum vulgare. Pharmaceutical Science and Technology, 3(1), 27-33. https://doi.org/10.11648/j.pst.20190301.14
ACS Style
Md. Ruhul Amin; Md. Abdullah-Al-Masum; Asma Kabir; Tofazzal Hossain Rubel; Md. Omar Faruqe, et al. Pharmacological Study on a Potential Medicinal Herb-Foeniculum vulgare. Pharm. Sci. Technol. 2019, 3(1), 27-33. doi: 10.11648/j.pst.20190301.14
AMA Style
Md. Ruhul Amin, Md. Abdullah-Al-Masum, Asma Kabir, Tofazzal Hossain Rubel, Md. Omar Faruqe, et al. Pharmacological Study on a Potential Medicinal Herb-Foeniculum vulgare. Pharm Sci Technol. 2019;3(1):27-33. doi: 10.11648/j.pst.20190301.14
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Download@article{10.11648/j.pst.20190301.14,
author = {Md. Ruhul Amin and Md. Abdullah-Al-Masum and Asma Kabir and Tofazzal Hossain Rubel and Md. Omar Faruqe and Md. Shahadat Hossain and Md Abu Torab and Md. Afjal Hossain and Md. Shahadat Hossain and Shafayet Ahmed Siddiqui},
title = {Pharmacological Study on a Potential Medicinal Herb-Foeniculum vulgare},
journal = {Pharmaceutical Science and Technology},
volume = {3},
number = {1},
pages = {27-33},
doi = {10.11648/j.pst.20190301.14},
url = {https://doi.org/10.11648/j.pst.20190301.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.pst.20190301.14},
abstract = {This study was conducted to investigate the antiemetic, antimicrobial and anti-radical activity of methanolic extracts of Foeniculum vulgare. The antiemetic assay was carried out by using chick emetic model with minor modifications by calculating the mean decrease in the number of retching. The antimicrobial activity of the crude extract was performed by Disc Diffusion method. The anti-radical activity was determined by the 2, 2-diphenyl-2-picrylhydrazyl hydrate (DPPH) method. The anti-emetic activity of Foeniculum vulgare leaves on young chicks revealed that these extracts have a less anti-emetic effect. The group of chicks treated with Chlorpromazine was found to have 60.6 retches as compared to the 66 retches of the control group, thus Chlorpromazine reduced the retches by 7.93%. The chickens treated with leaves extracts inhibited the retches up to 2.03%. The minimum antimicrobial effect was found in this methanol crude extract. The extract did not appear potent in terms of both zones of inhibition and spectrum of activity. In anti-radical activity test, the extract showed moderate free radical scavenging activity with IC50 value 240.39μg/ml. while compared to that of the reference standard ascorbic acid. Methanolic extract of Foeniculum vulgare leaves have minimum anti-emetic and anti-microbial activities and moderate anti-radical properties.},
year = {2019}
}
TY - JOUR T1 - Pharmacological Study on a Potential Medicinal Herb-Foeniculum vulgare AU - Md. Ruhul Amin AU - Md. Abdullah-Al-Masum AU - Asma Kabir AU - Tofazzal Hossain Rubel AU - Md. Omar Faruqe AU - Md. Shahadat Hossain AU - Md Abu Torab AU - Md. Afjal Hossain AU - Md. Shahadat Hossain AU - Shafayet Ahmed Siddiqui Y1 - 2019/09/03 PY - 2019 N1 - https://doi.org/10.11648/j.pst.20190301.14 DO - 10.11648/j.pst.20190301.14 T2 - Pharmaceutical Science and Technology JF - Pharmaceutical Science and Technology JO - Pharmaceutical Science and Technology SP - 27 EP - 33 PB - Science Publishing Group SN - 2640-4540 UR - https://doi.org/10.11648/j.pst.20190301.14 AB - This study was conducted to investigate the antiemetic, antimicrobial and anti-radical activity of methanolic extracts of Foeniculum vulgare. The antiemetic assay was carried out by using chick emetic model with minor modifications by calculating the mean decrease in the number of retching. The antimicrobial activity of the crude extract was performed by Disc Diffusion method. The anti-radical activity was determined by the 2, 2-diphenyl-2-picrylhydrazyl hydrate (DPPH) method. The anti-emetic activity of Foeniculum vulgare leaves on young chicks revealed that these extracts have a less anti-emetic effect. The group of chicks treated with Chlorpromazine was found to have 60.6 retches as compared to the 66 retches of the control group, thus Chlorpromazine reduced the retches by 7.93%. The chickens treated with leaves extracts inhibited the retches up to 2.03%. The minimum antimicrobial effect was found in this methanol crude extract. The extract did not appear potent in terms of both zones of inhibition and spectrum of activity. In anti-radical activity test, the extract showed moderate free radical scavenging activity with IC50 value 240.39μg/ml. while compared to that of the reference standard ascorbic acid. Methanolic extract of Foeniculum vulgare leaves have minimum anti-emetic and anti-microbial activities and moderate anti-radical properties. VL - 3 IS - 1 ER -
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