Urinary tract infection is among bacterial infections that provide antibiotic treatment. The overly systematic use of a single class of antibiotic induces a selection pressure leading to bacterial resistance. The purpose of this study is to evaluate the level of resistance and to follow the evolution of the sensitivity of uropathogenic bacteria to fosfomycin to allow a better antibiotherapy of urinary infections. This is a prospective 3-year study of all positive cytobacterioligical urine exam from inpatients or consultants who have arrived at the microbiology laboratory at the Avicenne Military Hospital in Marrakech. Of the 12,116 cytobacterioligical urine exam performed, 1788 met the criteria for urinary tract infection. These urinary infections mainly concerned patients followed externally (1471). The sex ratio between men and women is 1.07. Of the isolated uropathogenic bacteria, E. coli is the predominant strain (51% isolates). Uropathogenic bacteria were sensitive to fosfomycin in more than 90% of cases, and this sensitivity was favorable during the study period. On the other hand, a high frequency of resistance has been recorded for betalactamines, in particular amoxicillin and amoxicillin-clavulanic acid. Fosfomycin has excellent activity on bacteria of urinary tract infections so its single dose prescription would be effective in uncomplicated urinary tract infections.
| Published in | Pathology and Laboratory Medicine (Volume 2, Issue 2) |
| DOI | 10.11648/j.plm.20180202.14 |
| Page(s) | 47-50 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Cytobacterioligical Urine Exam, Uropathogenic Bacteria, Fosfomycin, Resistance
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APA Style
Zohair Ait Ouzdi, Lamiae Arsalane, Youssef El Kamouni, Said Zouhair. (2019). The Resistance of Uropathogenic Bacteria to Fosfomycin. Pathology and Laboratory Medicine, 2(2), 47-50. https://doi.org/10.11648/j.plm.20180202.14
ACS Style
Zohair Ait Ouzdi; Lamiae Arsalane; Youssef El Kamouni; Said Zouhair. The Resistance of Uropathogenic Bacteria to Fosfomycin. Pathol. Lab. Med. 2019, 2(2), 47-50. doi: 10.11648/j.plm.20180202.14
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Download@article{10.11648/j.plm.20180202.14,
author = {Zohair Ait Ouzdi and Lamiae Arsalane and Youssef El Kamouni and Said Zouhair},
title = {The Resistance of Uropathogenic Bacteria to Fosfomycin},
journal = {Pathology and Laboratory Medicine},
volume = {2},
number = {2},
pages = {47-50},
doi = {10.11648/j.plm.20180202.14},
url = {https://doi.org/10.11648/j.plm.20180202.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plm.20180202.14},
abstract = {Urinary tract infection is among bacterial infections that provide antibiotic treatment. The overly systematic use of a single class of antibiotic induces a selection pressure leading to bacterial resistance. The purpose of this study is to evaluate the level of resistance and to follow the evolution of the sensitivity of uropathogenic bacteria to fosfomycin to allow a better antibiotherapy of urinary infections. This is a prospective 3-year study of all positive cytobacterioligical urine exam from inpatients or consultants who have arrived at the microbiology laboratory at the Avicenne Military Hospital in Marrakech. Of the 12,116 cytobacterioligical urine exam performed, 1788 met the criteria for urinary tract infection. These urinary infections mainly concerned patients followed externally (1471). The sex ratio between men and women is 1.07. Of the isolated uropathogenic bacteria, E. coli is the predominant strain (51% isolates). Uropathogenic bacteria were sensitive to fosfomycin in more than 90% of cases, and this sensitivity was favorable during the study period. On the other hand, a high frequency of resistance has been recorded for betalactamines, in particular amoxicillin and amoxicillin-clavulanic acid. Fosfomycin has excellent activity on bacteria of urinary tract infections so its single dose prescription would be effective in uncomplicated urinary tract infections.},
year = {2019}
}
TY - JOUR T1 - The Resistance of Uropathogenic Bacteria to Fosfomycin AU - Zohair Ait Ouzdi AU - Lamiae Arsalane AU - Youssef El Kamouni AU - Said Zouhair Y1 - 2019/01/07 PY - 2019 N1 - https://doi.org/10.11648/j.plm.20180202.14 DO - 10.11648/j.plm.20180202.14 T2 - Pathology and Laboratory Medicine JF - Pathology and Laboratory Medicine JO - Pathology and Laboratory Medicine SP - 47 EP - 50 PB - Science Publishing Group SN - 2640-4478 UR - https://doi.org/10.11648/j.plm.20180202.14 AB - Urinary tract infection is among bacterial infections that provide antibiotic treatment. The overly systematic use of a single class of antibiotic induces a selection pressure leading to bacterial resistance. The purpose of this study is to evaluate the level of resistance and to follow the evolution of the sensitivity of uropathogenic bacteria to fosfomycin to allow a better antibiotherapy of urinary infections. This is a prospective 3-year study of all positive cytobacterioligical urine exam from inpatients or consultants who have arrived at the microbiology laboratory at the Avicenne Military Hospital in Marrakech. Of the 12,116 cytobacterioligical urine exam performed, 1788 met the criteria for urinary tract infection. These urinary infections mainly concerned patients followed externally (1471). The sex ratio between men and women is 1.07. Of the isolated uropathogenic bacteria, E. coli is the predominant strain (51% isolates). Uropathogenic bacteria were sensitive to fosfomycin in more than 90% of cases, and this sensitivity was favorable during the study period. On the other hand, a high frequency of resistance has been recorded for betalactamines, in particular amoxicillin and amoxicillin-clavulanic acid. Fosfomycin has excellent activity on bacteria of urinary tract infections so its single dose prescription would be effective in uncomplicated urinary tract infections. VL - 2 IS - 2 ER -
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