A Combined Clinical and Langmuir Film Study of Natural Tear Films

Ester Guaus; Carla Fàbregas; Miriam Pérez; Juan Torrent-Burgués

doi:doi:10.11648/j.ijovs.20170201.13

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A Combined Clinical and Langmuir Film Study of Natural Tear Films

Ester Guaus, Carla Fàbregas, Miriam Pérez, Juan Torrent-Burgués

Published in International Journal of Ophthalmology & Visual Science (Volume 2, Issue 1)

Received: 2 February 2017 Accepted: 23 February 2017 Published: 9 March 2017

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Abstract

The Langmuir technique has been applied to the study of natural tears and the results obtained from surface pressure-area isotherms have been correlated with those of clinical tests (the Schirmer and the TFBUT tests). The population studied only included people aged over 45. Natural tears were collected from Schirmer strips, which were placed in contact with the water subphase of a Langmuir trough for recording the surface pressure-area isotherms. These isotherms have been classified as good or weak according to the characteristics obtained. From the isotherms, characteristic values such as π_limit, C_S^-1_max and π_max were also obtained. The analysis from the Chi-squared test indicates dependence between the Schirmer test and the type of isotherms (P<0.05). In the case of the TFBUT test and the type of isotherms the value of P>0.05 indicates that the independence cannot be discarded with the significance criteria imposed. Working with the same criteria of significance, we obtain moderate or good Pearson correlation coefficients with statistical significance (P<0.05) between the values of the Schirmer test and the π_limit, C_S^-1_max and π_max values. On the other hand, we obtain low Pearson correlation coefficients with no statistical significance (P>0.05) between the values of the TFBUT test and the π_limit, C_S^-1_max and π_max values.

Published in	International Journal of Ophthalmology & Visual Science (Volume 2, Issue 1)
DOI	10.11648/j.ijovs.20170201.13
Page(s)	5-14
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Natural Tears, Surface Pressure-Area Isotherm, Elastic Modulus, Schirmer Test, Tear Film Break-Up-Time (TFBUT)

References

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APA Style

Ester Guaus, Carla Fàbregas, Miriam Pérez, Juan Torrent-Burgués. (2017). A Combined Clinical and Langmuir Film Study of Natural Tear Films. International Journal of Ophthalmology & Visual Science, 2(1), 5-14. https://doi.org/10.11648/j.ijovs.20170201.13

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ACS Style

Ester Guaus; Carla Fàbregas; Miriam Pérez; Juan Torrent-Burgués. A Combined Clinical and Langmuir Film Study of Natural Tear Films. Int. J. Ophthalmol. Vis. Sci. 2017, 2(1), 5-14. doi: 10.11648/j.ijovs.20170201.13

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AMA Style

Ester Guaus, Carla Fàbregas, Miriam Pérez, Juan Torrent-Burgués. A Combined Clinical and Langmuir Film Study of Natural Tear Films. Int J Ophthalmol Vis Sci. 2017;2(1):5-14. doi: 10.11648/j.ijovs.20170201.13

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@article{10.11648/j.ijovs.20170201.13,
  author = {Ester Guaus and Carla Fàbregas and Miriam Pérez and Juan Torrent-Burgués},
  title = {A Combined Clinical and Langmuir Film Study of Natural Tear Films},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {2},
  number = {1},
  pages = {5-14},
  doi = {10.11648/j.ijovs.20170201.13},
  url = {https://doi.org/10.11648/j.ijovs.20170201.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20170201.13},
  abstract = {The Langmuir technique has been applied to the study of natural tears and the results obtained from surface pressure-area isotherms have been correlated with those of clinical tests (the Schirmer and the TFBUT tests). The population studied only included people aged over 45. Natural tears were collected from Schirmer strips, which were placed in contact with the water subphase of a Langmuir trough for recording the surface pressure-area isotherms. These isotherms have been classified as good or weak according to the characteristics obtained. From the isotherms, characteristic values such as πlimit, CS-1max and πmax were also obtained. The analysis from the Chi-squared test indicates dependence between the Schirmer test and the type of isotherms (P<0.05). In the case of the TFBUT test and the type of isotherms the value of P>0.05 indicates that the independence cannot be discarded with the significance criteria imposed. Working with the same criteria of significance, we obtain moderate or good Pearson correlation coefficients with statistical significance (P<0.05) between the values of the Schirmer test and the πlimit, CS-1max and πmax values. On the other hand, we obtain low Pearson correlation coefficients with no statistical significance (P>0.05) between the values of the TFBUT test and the πlimit, CS-1max and πmax values.},
 year = {2017}
}

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TY  - JOUR
T1  - A Combined Clinical and Langmuir Film Study of Natural Tear Films
AU  - Ester Guaus
AU  - Carla Fàbregas
AU  - Miriam Pérez
AU  - Juan Torrent-Burgués
Y1  - 2017/03/09
PY  - 2017
N1  - https://doi.org/10.11648/j.ijovs.20170201.13
DO  - 10.11648/j.ijovs.20170201.13
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 5
EP  - 14
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20170201.13
AB  - The Langmuir technique has been applied to the study of natural tears and the results obtained from surface pressure-area isotherms have been correlated with those of clinical tests (the Schirmer and the TFBUT tests). The population studied only included people aged over 45. Natural tears were collected from Schirmer strips, which were placed in contact with the water subphase of a Langmuir trough for recording the surface pressure-area isotherms. These isotherms have been classified as good or weak according to the characteristics obtained. From the isotherms, characteristic values such as πlimit, CS-1max and πmax were also obtained. The analysis from the Chi-squared test indicates dependence between the Schirmer test and the type of isotherms (P<0.05). In the case of the TFBUT test and the type of isotherms the value of P>0.05 indicates that the independence cannot be discarded with the significance criteria imposed. Working with the same criteria of significance, we obtain moderate or good Pearson correlation coefficients with statistical significance (P<0.05) between the values of the Schirmer test and the πlimit, CS-1max and πmax values. On the other hand, we obtain low Pearson correlation coefficients with no statistical significance (P>0.05) between the values of the TFBUT test and the πlimit, CS-1max and πmax values.
VL  - 2
IS  - 1
ER  -

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Author Information

Ester Guaus

Faculty of Optics and Optometry, Department of Chemical Engineering, Universitat Politècnica de Catalunya, C/ Violinista Vellsolà, Terrassa (Barcelona), Spain
Carla Fàbregas

Faculty of Optics and Optometry, Department of Chemical Engineering, Universitat Politècnica de Catalunya, C/ Violinista Vellsolà, Terrassa (Barcelona), Spain
Miriam Pérez

Faculty of Optics and Optometry, Department of Chemical Engineering, Universitat Politècnica de Catalunya, C/ Violinista Vellsolà, Terrassa (Barcelona), Spain
Juan Torrent-Burgués

Faculty of Optics and Optometry, Department of Chemical Engineering, Universitat Politècnica de Catalunya, C/ Violinista Vellsolà, Terrassa (Barcelona), Spain

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APA Style

Ester Guaus, Carla Fàbregas, Miriam Pérez, Juan Torrent-Burgués. (2017). A Combined Clinical and Langmuir Film Study of Natural Tear Films. International Journal of Ophthalmology & Visual Science, 2(1), 5-14. https://doi.org/10.11648/j.ijovs.20170201.13

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ACS Style

Ester Guaus; Carla Fàbregas; Miriam Pérez; Juan Torrent-Burgués. A Combined Clinical and Langmuir Film Study of Natural Tear Films. Int. J. Ophthalmol. Vis. Sci. 2017, 2(1), 5-14. doi: 10.11648/j.ijovs.20170201.13

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AMA Style

Ester Guaus, Carla Fàbregas, Miriam Pérez, Juan Torrent-Burgués. A Combined Clinical and Langmuir Film Study of Natural Tear Films. Int J Ophthalmol Vis Sci. 2017;2(1):5-14. doi: 10.11648/j.ijovs.20170201.13

Copy | Download

@article{10.11648/j.ijovs.20170201.13,
  author = {Ester Guaus and Carla Fàbregas and Miriam Pérez and Juan Torrent-Burgués},
  title = {A Combined Clinical and Langmuir Film Study of Natural Tear Films},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {2},
  number = {1},
  pages = {5-14},
  doi = {10.11648/j.ijovs.20170201.13},
  url = {https://doi.org/10.11648/j.ijovs.20170201.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20170201.13},
  abstract = {The Langmuir technique has been applied to the study of natural tears and the results obtained from surface pressure-area isotherms have been correlated with those of clinical tests (the Schirmer and the TFBUT tests). The population studied only included people aged over 45. Natural tears were collected from Schirmer strips, which were placed in contact with the water subphase of a Langmuir trough for recording the surface pressure-area isotherms. These isotherms have been classified as good or weak according to the characteristics obtained. From the isotherms, characteristic values such as πlimit, CS-1max and πmax were also obtained. The analysis from the Chi-squared test indicates dependence between the Schirmer test and the type of isotherms (P<0.05). In the case of the TFBUT test and the type of isotherms the value of P>0.05 indicates that the independence cannot be discarded with the significance criteria imposed. Working with the same criteria of significance, we obtain moderate or good Pearson correlation coefficients with statistical significance (P<0.05) between the values of the Schirmer test and the πlimit, CS-1max and πmax values. On the other hand, we obtain low Pearson correlation coefficients with no statistical significance (P>0.05) between the values of the TFBUT test and the πlimit, CS-1max and πmax values.},
 year = {2017}
}

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TY  - JOUR
T1  - A Combined Clinical and Langmuir Film Study of Natural Tear Films
AU  - Ester Guaus
AU  - Carla Fàbregas
AU  - Miriam Pérez
AU  - Juan Torrent-Burgués
Y1  - 2017/03/09
PY  - 2017
N1  - https://doi.org/10.11648/j.ijovs.20170201.13
DO  - 10.11648/j.ijovs.20170201.13
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 5
EP  - 14
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20170201.13
AB  - The Langmuir technique has been applied to the study of natural tears and the results obtained from surface pressure-area isotherms have been correlated with those of clinical tests (the Schirmer and the TFBUT tests). The population studied only included people aged over 45. Natural tears were collected from Schirmer strips, which were placed in contact with the water subphase of a Langmuir trough for recording the surface pressure-area isotherms. These isotherms have been classified as good or weak according to the characteristics obtained. From the isotherms, characteristic values such as πlimit, CS-1max and πmax were also obtained. The analysis from the Chi-squared test indicates dependence between the Schirmer test and the type of isotherms (P<0.05). In the case of the TFBUT test and the type of isotherms the value of P>0.05 indicates that the independence cannot be discarded with the significance criteria imposed. Working with the same criteria of significance, we obtain moderate or good Pearson correlation coefficients with statistical significance (P<0.05) between the values of the Schirmer test and the πlimit, CS-1max and πmax values. On the other hand, we obtain low Pearson correlation coefficients with no statistical significance (P>0.05) between the values of the TFBUT test and the πlimit, CS-1max and πmax values.
VL  - 2
IS  - 1
ER  -

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