miR-203, as a member of the miRNAs family, play a major role in control of gene expression during normal development and are disrupted in the initiation and progression of specific diseases. It was worth nothing that a growing body of evidence indicated an abnormal expression of miR-203 in several human leading cancers including gastrointestinal and urogenital cancers. The cytosine-phosphoguanine (CpG)-island methylation was one of the most significant factors which controlled the expression of miR-203. Furthermore, miR-203 participated in these cancers via targeting its downstream genes. However, the precise regulatory mechanisms underlying miR-203 association with these cancers are still not fully understood. The aim of this review is to sum up the collective knowledge of miR-203 in gastrointestinal and urogenital cancers.
| Published in | International Journal of Animal Science and Technology (Volume 1, Issue 1) |
| DOI | 10.11648/j.ijast.20170101.12 |
| Page(s) | 5-14 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2018. Published by Science Publishing Group |
miR-203, Gastrointestinal Cancers, Urogenital Cancers, Methylation, Targeting
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APA Style
Lei Zhan, Bing Wei. (2018). The Amphibolous Role of miR-203 in Gastrointestinal and Urogenital Cancers. International Journal of Animal Science and Technology, 1(1), 5-14. https://doi.org/10.11648/j.ijast.20170101.12
ACS Style
Lei Zhan; Bing Wei. The Amphibolous Role of miR-203 in Gastrointestinal and Urogenital Cancers. Int. J. Anim. Sci. Technol. 2018, 1(1), 5-14. doi: 10.11648/j.ijast.20170101.12
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Download@article{10.11648/j.ijast.20170101.12,
author = {Lei Zhan and Bing Wei},
title = {The Amphibolous Role of miR-203 in Gastrointestinal and Urogenital Cancers},
journal = {International Journal of Animal Science and Technology},
volume = {1},
number = {1},
pages = {5-14},
doi = {10.11648/j.ijast.20170101.12},
url = {https://doi.org/10.11648/j.ijast.20170101.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijast.20170101.12},
abstract = {miR-203, as a member of the miRNAs family, play a major role in control of gene expression during normal development and are disrupted in the initiation and progression of specific diseases. It was worth nothing that a growing body of evidence indicated an abnormal expression of miR-203 in several human leading cancers including gastrointestinal and urogenital cancers. The cytosine-phosphoguanine (CpG)-island methylation was one of the most significant factors which controlled the expression of miR-203. Furthermore, miR-203 participated in these cancers via targeting its downstream genes. However, the precise regulatory mechanisms underlying miR-203 association with these cancers are still not fully understood. The aim of this review is to sum up the collective knowledge of miR-203 in gastrointestinal and urogenital cancers.},
year = {2018}
}
TY - JOUR T1 - The Amphibolous Role of miR-203 in Gastrointestinal and Urogenital Cancers AU - Lei Zhan AU - Bing Wei Y1 - 2018/01/03 PY - 2018 N1 - https://doi.org/10.11648/j.ijast.20170101.12 DO - 10.11648/j.ijast.20170101.12 T2 - International Journal of Animal Science and Technology JF - International Journal of Animal Science and Technology JO - International Journal of Animal Science and Technology SP - 5 EP - 14 PB - Science Publishing Group SN - 2640-1312 UR - https://doi.org/10.11648/j.ijast.20170101.12 AB - miR-203, as a member of the miRNAs family, play a major role in control of gene expression during normal development and are disrupted in the initiation and progression of specific diseases. It was worth nothing that a growing body of evidence indicated an abnormal expression of miR-203 in several human leading cancers including gastrointestinal and urogenital cancers. The cytosine-phosphoguanine (CpG)-island methylation was one of the most significant factors which controlled the expression of miR-203. Furthermore, miR-203 participated in these cancers via targeting its downstream genes. However, the precise regulatory mechanisms underlying miR-203 association with these cancers are still not fully understood. The aim of this review is to sum up the collective knowledge of miR-203 in gastrointestinal and urogenital cancers. VL - 1 IS - 1 ER -
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