Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study

Christopher Edet Ekpenyong; Inyang Udoinyang Clement; Caleb Effiong Edet

doi:doi:10.11648/j.ejcbs.20190502.11

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Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study

Christopher Edet Ekpenyong, Inyang Udoinyang Clement, Caleb Effiong Edet

Published in European Journal of Clinical and Biomedical Sciences (Volume 5, Issue 2)

Received: 20 February 2019 Accepted: 25 March 2019 Published: 23 May 2019

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Abstract

Despite the increasing prevalence of hyperuricemia in the general population and its association with many diseases, serum uric acid (SUA) level has not been routinely determined in the evaluation and management of patients, especially those with metabolic disorders. This cross-sectional study used standard methods to assess the influence of personal characteristics, lifestyle and cardio-metabolic status on SUA levels of patients who visited a primary care center in Southern Nigeria. Forty-nine point seven percent of participants were hyperuricemic. Significant association and higher odds for hyperuricemia were found among participants who were married (Odd Ratio (OR)=2.24,95%Confidence interval (C.I) 1.947-5.303), dehydrated (OR=1.46,C.I 0.845-2.535), currently consuming alcohol (OR=5.199, C.I 4.249-69.623), with poor dietary habits (OR=1.23,C.I0.982-7.2356), physically inactive (OR=2.760,C.I 0.294-25.881), night clubbing (OR=3.09,C.I3.22-12.982), frequently drinking soft/sweet drinks (OR=3.42,C.I 2.01-10.29), abnormal anthropometric profile (OR=1.27,CI 1.094-1.485) for BMI and OR=1.52,C.I 0.874-2.656) for waist circumference) and metabolic disorders including hypertension (OR=1.60,C.I 1.280-2.008), T2DM (OR=1.27,C.I 1.089-1.474), dyslipidemia and musculoskeletal disorders (OR=3.26,C.I1.633-6.492). Demographic factors, poor lifestyle habits, abnormal adiposity and metabolic aberrations drive hyperuricemia and therefore underline the need for SUA evaluation and management among those with these characteristics to prevent associated diseases.

Published in	European Journal of Clinical and Biomedical Sciences (Volume 5, Issue 2)
DOI	10.11648/j.ejcbs.20190502.11
Page(s)	27-38
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Hyperuricemia, Lifestyle, Demographics, Dysmetabolic Syndrome

References

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Christopher Edet Ekpenyong, Inyang Udoinyang Clement, Caleb Effiong Edet. (2019). Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study. European Journal of Clinical and Biomedical Sciences, 5(2), 27-38. https://doi.org/10.11648/j.ejcbs.20190502.11

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Christopher Edet Ekpenyong; Inyang Udoinyang Clement; Caleb Effiong Edet. Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study. Eur. J. Clin. Biomed. Sci. 2019, 5(2), 27-38. doi: 10.11648/j.ejcbs.20190502.11

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AMA Style

Christopher Edet Ekpenyong, Inyang Udoinyang Clement, Caleb Effiong Edet. Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study. Eur J Clin Biomed Sci. 2019;5(2):27-38. doi: 10.11648/j.ejcbs.20190502.11

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@article{10.11648/j.ejcbs.20190502.11,
  author = {Christopher Edet Ekpenyong and Inyang Udoinyang Clement and Caleb Effiong Edet},
  title = {Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {5},
  number = {2},
  pages = {27-38},
  doi = {10.11648/j.ejcbs.20190502.11},
  url = {https://doi.org/10.11648/j.ejcbs.20190502.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20190502.11},
  abstract = {Despite the increasing prevalence of hyperuricemia in the general population and its association with many diseases, serum uric acid (SUA) level has not been routinely determined in the evaluation and management of patients, especially those with metabolic disorders. This cross-sectional study used standard methods to assess the influence of personal characteristics, lifestyle and cardio-metabolic status on SUA levels of patients who visited a primary care center in Southern Nigeria. Forty-nine point seven percent of participants were hyperuricemic. Significant association and higher odds for hyperuricemia were found among participants who were married (Odd Ratio (OR)=2.24,95%Confidence interval (C.I) 1.947-5.303), dehydrated (OR=1.46,C.I 0.845-2.535), currently consuming alcohol (OR=5.199, C.I 4.249-69.623), with poor dietary habits (OR=1.23,C.I0.982-7.2356), physically inactive (OR=2.760,C.I 0.294-25.881), night clubbing (OR=3.09,C.I3.22-12.982), frequently drinking soft/sweet drinks (OR=3.42,C.I 2.01-10.29), abnormal anthropometric profile (OR=1.27,CI 1.094-1.485) for BMI and OR=1.52,C.I 0.874-2.656) for waist circumference) and metabolic disorders including hypertension (OR=1.60,C.I 1.280-2.008), T2DM (OR=1.27,C.I 1.089-1.474), dyslipidemia and musculoskeletal disorders (OR=3.26,C.I1.633-6.492). Demographic factors, poor lifestyle habits, abnormal adiposity and metabolic aberrations drive hyperuricemia and therefore underline the need for SUA evaluation and management among those with these characteristics to prevent associated diseases.},
 year = {2019}
}

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TY  - JOUR
T1  - Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study
AU  - Christopher Edet Ekpenyong
AU  - Inyang Udoinyang Clement
AU  - Caleb Effiong Edet
Y1  - 2019/05/23
PY  - 2019
N1  - https://doi.org/10.11648/j.ejcbs.20190502.11
DO  - 10.11648/j.ejcbs.20190502.11
T2  - European Journal of Clinical and Biomedical Sciences
JF  - European Journal of Clinical and Biomedical Sciences
JO  - European Journal of Clinical and Biomedical Sciences
SP  - 27
EP  - 38
PB  - Science Publishing Group
SN  - 2575-5005
UR  - https://doi.org/10.11648/j.ejcbs.20190502.11
AB  - Despite the increasing prevalence of hyperuricemia in the general population and its association with many diseases, serum uric acid (SUA) level has not been routinely determined in the evaluation and management of patients, especially those with metabolic disorders. This cross-sectional study used standard methods to assess the influence of personal characteristics, lifestyle and cardio-metabolic status on SUA levels of patients who visited a primary care center in Southern Nigeria. Forty-nine point seven percent of participants were hyperuricemic. Significant association and higher odds for hyperuricemia were found among participants who were married (Odd Ratio (OR)=2.24,95%Confidence interval (C.I) 1.947-5.303), dehydrated (OR=1.46,C.I 0.845-2.535), currently consuming alcohol (OR=5.199, C.I 4.249-69.623), with poor dietary habits (OR=1.23,C.I0.982-7.2356), physically inactive (OR=2.760,C.I 0.294-25.881), night clubbing (OR=3.09,C.I3.22-12.982), frequently drinking soft/sweet drinks (OR=3.42,C.I 2.01-10.29), abnormal anthropometric profile (OR=1.27,CI 1.094-1.485) for BMI and OR=1.52,C.I 0.874-2.656) for waist circumference) and metabolic disorders including hypertension (OR=1.60,C.I 1.280-2.008), T2DM (OR=1.27,C.I 1.089-1.474), dyslipidemia and musculoskeletal disorders (OR=3.26,C.I1.633-6.492). Demographic factors, poor lifestyle habits, abnormal adiposity and metabolic aberrations drive hyperuricemia and therefore underline the need for SUA evaluation and management among those with these characteristics to prevent associated diseases.
VL  - 5
IS  - 2
ER  -

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Author Information

Christopher Edet Ekpenyong

Department of Physiology, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria
Inyang Udoinyang Clement

Department of Orthopedics and Traumatology, Faculty of Clinical Sciences, University of Uyo, Nigeria
Caleb Effiong Edet

Department of Physiology, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria

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Christopher Edet Ekpenyong, Inyang Udoinyang Clement, Caleb Effiong Edet. (2019). Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study. European Journal of Clinical and Biomedical Sciences, 5(2), 27-38. https://doi.org/10.11648/j.ejcbs.20190502.11

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Christopher Edet Ekpenyong; Inyang Udoinyang Clement; Caleb Effiong Edet. Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study. Eur. J. Clin. Biomed. Sci. 2019, 5(2), 27-38. doi: 10.11648/j.ejcbs.20190502.11

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AMA Style

Christopher Edet Ekpenyong, Inyang Udoinyang Clement, Caleb Effiong Edet. Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study. Eur J Clin Biomed Sci. 2019;5(2):27-38. doi: 10.11648/j.ejcbs.20190502.11

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@article{10.11648/j.ejcbs.20190502.11,
  author = {Christopher Edet Ekpenyong and Inyang Udoinyang Clement and Caleb Effiong Edet},
  title = {Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {5},
  number = {2},
  pages = {27-38},
  doi = {10.11648/j.ejcbs.20190502.11},
  url = {https://doi.org/10.11648/j.ejcbs.20190502.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20190502.11},
  abstract = {Despite the increasing prevalence of hyperuricemia in the general population and its association with many diseases, serum uric acid (SUA) level has not been routinely determined in the evaluation and management of patients, especially those with metabolic disorders. This cross-sectional study used standard methods to assess the influence of personal characteristics, lifestyle and cardio-metabolic status on SUA levels of patients who visited a primary care center in Southern Nigeria. Forty-nine point seven percent of participants were hyperuricemic. Significant association and higher odds for hyperuricemia were found among participants who were married (Odd Ratio (OR)=2.24,95%Confidence interval (C.I) 1.947-5.303), dehydrated (OR=1.46,C.I 0.845-2.535), currently consuming alcohol (OR=5.199, C.I 4.249-69.623), with poor dietary habits (OR=1.23,C.I0.982-7.2356), physically inactive (OR=2.760,C.I 0.294-25.881), night clubbing (OR=3.09,C.I3.22-12.982), frequently drinking soft/sweet drinks (OR=3.42,C.I 2.01-10.29), abnormal anthropometric profile (OR=1.27,CI 1.094-1.485) for BMI and OR=1.52,C.I 0.874-2.656) for waist circumference) and metabolic disorders including hypertension (OR=1.60,C.I 1.280-2.008), T2DM (OR=1.27,C.I 1.089-1.474), dyslipidemia and musculoskeletal disorders (OR=3.26,C.I1.633-6.492). Demographic factors, poor lifestyle habits, abnormal adiposity and metabolic aberrations drive hyperuricemia and therefore underline the need for SUA evaluation and management among those with these characteristics to prevent associated diseases.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Risk Factors for Undiagnosed Hyperuricemia and Gout: Influence of Personal Characteristics, Life Style and Cardio-Metabolic Status: A Cross Sectional Study
AU  - Christopher Edet Ekpenyong
AU  - Inyang Udoinyang Clement
AU  - Caleb Effiong Edet
Y1  - 2019/05/23
PY  - 2019
N1  - https://doi.org/10.11648/j.ejcbs.20190502.11
DO  - 10.11648/j.ejcbs.20190502.11
T2  - European Journal of Clinical and Biomedical Sciences
JF  - European Journal of Clinical and Biomedical Sciences
JO  - European Journal of Clinical and Biomedical Sciences
SP  - 27
EP  - 38
PB  - Science Publishing Group
SN  - 2575-5005
UR  - https://doi.org/10.11648/j.ejcbs.20190502.11
AB  - Despite the increasing prevalence of hyperuricemia in the general population and its association with many diseases, serum uric acid (SUA) level has not been routinely determined in the evaluation and management of patients, especially those with metabolic disorders. This cross-sectional study used standard methods to assess the influence of personal characteristics, lifestyle and cardio-metabolic status on SUA levels of patients who visited a primary care center in Southern Nigeria. Forty-nine point seven percent of participants were hyperuricemic. Significant association and higher odds for hyperuricemia were found among participants who were married (Odd Ratio (OR)=2.24,95%Confidence interval (C.I) 1.947-5.303), dehydrated (OR=1.46,C.I 0.845-2.535), currently consuming alcohol (OR=5.199, C.I 4.249-69.623), with poor dietary habits (OR=1.23,C.I0.982-7.2356), physically inactive (OR=2.760,C.I 0.294-25.881), night clubbing (OR=3.09,C.I3.22-12.982), frequently drinking soft/sweet drinks (OR=3.42,C.I 2.01-10.29), abnormal anthropometric profile (OR=1.27,CI 1.094-1.485) for BMI and OR=1.52,C.I 0.874-2.656) for waist circumference) and metabolic disorders including hypertension (OR=1.60,C.I 1.280-2.008), T2DM (OR=1.27,C.I 1.089-1.474), dyslipidemia and musculoskeletal disorders (OR=3.26,C.I1.633-6.492). Demographic factors, poor lifestyle habits, abnormal adiposity and metabolic aberrations drive hyperuricemia and therefore underline the need for SUA evaluation and management among those with these characteristics to prevent associated diseases.
VL  - 5
IS  - 2
ER  -

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