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Endoscopic Nasobiliary Drainage Help to Prevent the Postoperative Complications of ERCP for Choledocholith Removal

Received: 15 August 2016     Accepted: 17 November 2016     Published: 17 December 2016
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Abstract

Aims: In order to investigate the preventive effect of endoscopic nasobiliary drainage (ENBD) on the postoperative complications of ERCP with endoscopic sphincterotomy (EST) for choledocholith. Methods: we collected 180 patients with choledocholith who received the treatment of ERCP for extracting stones between January 2007 and June 2009. All of the 180 patients were divided into two groups: the ENBD group which, including 80 patients, were placed with ENBD, and the control group, including the residual 100 patients, were not placed with ENBD. We measured the scrum amylase levels within 24 hours, before and after ERCP. Meanwhile, the incidences of hyperamylasemia, acute pancreatitis, cholangitis and sphincter of Oddi dysfunction (SOD) were observed after ERCP. Results: The ENBD group shown lower scrum amylase levels after ERCP (225.78±178.62 vs. 563.08±201.24, P<0.05) than control group, while not significant difference existed between these two groups (130.25±35.20 vs. 145.35±45.34, P>0.05) before ERCP. At the same time, ENBD group were found with less incidences of hyperamylasemia (5% vs. 18%, P<0.05), acute pancreatitis (2.5% vs. 8%, P<0.05) and SOD (5% vs. 20%, P<0.05), but not different in cholangitis (2.5% vs. 3%, P>0.05) than control group. Conclusion: Out results suggested that ENBD can prevent the complications of hyperamylasemia, acute pancreatitis and SOD after ERCP effectively.

Published in European Journal of Clinical and Biomedical Sciences (Volume 2, Issue 6)
DOI 10.11648/j.ejcbs.20160206.14
Page(s) 83-86
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Endoscopic Retrograde Cholangiopancreatography, Endoscopic Nasobiliary Drainage, Endoscopic Sphincterotomy, Hyperamylasemia, Acute Pancreatitis, Cholangitis

References
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[2] Cotton PB, Lehman G, Vennes J, et al. Endoscopic sphincterotomy complications and their management: an attempt at consensus [J]. Gastrointest Endosc, 1991, 37 (12): 383-393.
[3] Kozarek RA, Ball TJ, Patterson DJ, et al. Endoscopic pancreatic duct sphincterotomy: indications, technique, and analysis of results [J]. Gastrointest Endosc, 1994, 40 (13): 592-598.
[4] Sherman S, Lehman GA. Endoscopic pancreatic sphincterotomy: techniques and complications [J]. Gastrointest Endosc Clin N Am, 1998, 8 (2): 115-124.
[5] Freeman ML, DiSario JA, Nelson DB, et al. Risk factors for post-ERCP pancreati- tis: a prospective, multicenter study [J]. Gastrointest Endosc, 2001, 54 (4): 425-434.
[6] Masci E, Toti G, Mariani A, et al. Complications of diagnostic and therapeutic ERCP: a prospective multicenter study [J]. Am J Gastroenterol, 2001, 96 (2): 417-423.
[7] Li ZS, Xu GM, Kong ZX, et al. Complications of diagnostic ERCP and treatment [J]. Chinese Journal of Digestive Endoscopy, 2002, 19 (2): 77-81.
[8] Freeman ML, Nelson DB, Sherman S, et al. Complications of endoscopic biliary Sphincterotomy [J]. N Engl J Med, 1996, 33 (5): 909–918.
[9] Tang SJ, Mayo MJ, Rodriguez-Frias E, et al. Safety and utility of ERCP during pregnancy [J]. Gastrointest Endosc, 2009, 69 (3): 453.
[10] Masci E, Toti G, Mariani A, et al. Complications of diagnostic and therapeutic ERCP: a p rospective multicenter study [J]. Am J Gastroenterol, 2001, 9 (6): 417–423.
[11] Mandryka Y, Klimczak J, Duszewski M, et al. Bile duct infections as a late complication after endoscopic sphincterotomy [J]. Pol Merkur Lekarski, 2006, 21 (126): 525.
[12] Wang HJ, Zhan ZG, Yan JF. Clinical analysis of pancreatitis and hyperamylasemia prevented after ERCP following endoscopic nasobiliary drainage [J]. Pancreatic disease science, 2007, 7 (2): 119.
[13] Chen WF, Yao LQ. Postoperative complications of ERCP and EST progress in the prevention and treatment [J]. China Practical Medicine, 2004, 6 (8):66-67.
[14] Loperfido S, Angelini G, Benedetti G, et al. Major early complications from diagnostic and therapeutic ERCP: a prospective multicenter study [J]. Gastrointest Endosc. 1998, 48 (1): 1-10.
[15] Quallich LG, Stern MA, Rich M, et al. Bile duct crystals do not contribute to sphincter of Oddi dysfunction [J]. Gastrointest Endosc 2002, 55 (23): 163-166.
[16] Tzovaras G, Rowlands BJ. Transduodenal sphincteroplasty and transampullary septectomy for sphincter of Oddi dysfunction [J]. Ann R Coll Surg Engl 2002, 8 (4): 14-19.
[17] Xing GP, Wang HY, Yu XP, et al. clinical analysis of 391 cases of common bile duct stones with ERCP, EST and ENBD treatment of [J]. Journal of Clinical Gastroenterology, 2007, 19 (4): 245-246.
Cite This Article
  • APA Style

    Zhu Qingyun, Pan Xinting, Wang Yunlong, Liu Fuguo, Sun Yunbo, et al. (2016). Endoscopic Nasobiliary Drainage Help to Prevent the Postoperative Complications of ERCP for Choledocholith Removal. European Journal of Clinical and Biomedical Sciences, 2(6), 83-86. https://doi.org/10.11648/j.ejcbs.20160206.14

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    ACS Style

    Zhu Qingyun; Pan Xinting; Wang Yunlong; Liu Fuguo; Sun Yunbo, et al. Endoscopic Nasobiliary Drainage Help to Prevent the Postoperative Complications of ERCP for Choledocholith Removal. Eur. J. Clin. Biomed. Sci. 2016, 2(6), 83-86. doi: 10.11648/j.ejcbs.20160206.14

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    AMA Style

    Zhu Qingyun, Pan Xinting, Wang Yunlong, Liu Fuguo, Sun Yunbo, et al. Endoscopic Nasobiliary Drainage Help to Prevent the Postoperative Complications of ERCP for Choledocholith Removal. Eur J Clin Biomed Sci. 2016;2(6):83-86. doi: 10.11648/j.ejcbs.20160206.14

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  • @article{10.11648/j.ejcbs.20160206.14,
      author = {Zhu Qingyun and Pan Xinting and Wang Yunlong and Liu Fuguo and Sun Yunbo and Li Liandi and Yu Bangxu and Jiang Wenbin and Li Kun and Wang Huimin and Sui Na},
      title = {Endoscopic Nasobiliary Drainage Help to Prevent the Postoperative Complications of ERCP for Choledocholith Removal},
      journal = {European Journal of Clinical and Biomedical Sciences},
      volume = {2},
      number = {6},
      pages = {83-86},
      doi = {10.11648/j.ejcbs.20160206.14},
      url = {https://doi.org/10.11648/j.ejcbs.20160206.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20160206.14},
      abstract = {Aims: In order to investigate the preventive effect of endoscopic nasobiliary drainage (ENBD) on the postoperative complications of ERCP with endoscopic sphincterotomy (EST) for choledocholith. Methods: we collected 180 patients with choledocholith who received the treatment of ERCP for extracting stones between January 2007 and June 2009. All of the 180 patients were divided into two groups: the ENBD group which, including 80 patients, were placed with ENBD, and the control group, including the residual 100 patients, were not placed with ENBD. We measured the scrum amylase levels within 24 hours, before and after ERCP. Meanwhile, the incidences of hyperamylasemia, acute pancreatitis, cholangitis and sphincter of Oddi dysfunction (SOD) were observed after ERCP. Results: The ENBD group shown lower scrum amylase levels after ERCP (225.78±178.62 vs. 563.08±201.24, P0.05) before ERCP. At the same time, ENBD group were found with less incidences of hyperamylasemia (5% vs. 18%, P0.05) than control group. Conclusion: Out results suggested that ENBD can prevent the complications of hyperamylasemia, acute pancreatitis and SOD after ERCP effectively.},
     year = {2016}
    }
    

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  • TY  - JOUR
    T1  - Endoscopic Nasobiliary Drainage Help to Prevent the Postoperative Complications of ERCP for Choledocholith Removal
    AU  - Zhu Qingyun
    AU  - Pan Xinting
    AU  - Wang Yunlong
    AU  - Liu Fuguo
    AU  - Sun Yunbo
    AU  - Li Liandi
    AU  - Yu Bangxu
    AU  - Jiang Wenbin
    AU  - Li Kun
    AU  - Wang Huimin
    AU  - Sui Na
    Y1  - 2016/12/17
    PY  - 2016
    N1  - https://doi.org/10.11648/j.ejcbs.20160206.14
    DO  - 10.11648/j.ejcbs.20160206.14
    T2  - European Journal of Clinical and Biomedical Sciences
    JF  - European Journal of Clinical and Biomedical Sciences
    JO  - European Journal of Clinical and Biomedical Sciences
    SP  - 83
    EP  - 86
    PB  - Science Publishing Group
    SN  - 2575-5005
    UR  - https://doi.org/10.11648/j.ejcbs.20160206.14
    AB  - Aims: In order to investigate the preventive effect of endoscopic nasobiliary drainage (ENBD) on the postoperative complications of ERCP with endoscopic sphincterotomy (EST) for choledocholith. Methods: we collected 180 patients with choledocholith who received the treatment of ERCP for extracting stones between January 2007 and June 2009. All of the 180 patients were divided into two groups: the ENBD group which, including 80 patients, were placed with ENBD, and the control group, including the residual 100 patients, were not placed with ENBD. We measured the scrum amylase levels within 24 hours, before and after ERCP. Meanwhile, the incidences of hyperamylasemia, acute pancreatitis, cholangitis and sphincter of Oddi dysfunction (SOD) were observed after ERCP. Results: The ENBD group shown lower scrum amylase levels after ERCP (225.78±178.62 vs. 563.08±201.24, P0.05) before ERCP. At the same time, ENBD group were found with less incidences of hyperamylasemia (5% vs. 18%, P0.05) than control group. Conclusion: Out results suggested that ENBD can prevent the complications of hyperamylasemia, acute pancreatitis and SOD after ERCP effectively.
    VL  - 2
    IS  - 6
    ER  - 

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Author Information
  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

  • The Intensive Care Unit of the Affiliated Hospital of Qingdao University, Qingdao, China

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