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Stability Analysis of Formulated Emulsion Containing Black Cumin (Nigella sativa) Oil

Received: 6 May 2016     Accepted: 16 May 2016     Published: 28 May 2016
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Abstract

In this present study emulsions were prepared by using black cumin oil. Dry gum method was followed to prepare emulsions formula A & B. Stability tests including organoleptic property evaluation, pH test, accelerated stability studies, water-drop test and peroxide value were determined. In case of organoleptic property evaluation emulsions showed insignificant changes and there were no variation in pH in both preparations up to 3 months. Emulsions were also undergone to different temperature effects and centrifugation at 4000 rpm, but lost the homogenous structure and separated into two phases under the effect of light and centrifugation. The study showed better results for emulsion B comparing with emulsion A. Thus our results showed that emulsion formulation B can be a good semi-solid preparation in Pharmaceutical field and food industry.

Published in American Journal of Biomedical and Life Sciences (Volume 4, Issue 3)
DOI 10.11648/j.ajbls.20160403.15
Page(s) 49-53
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Black Cumin Oil, Emulsions, Dry Gum Method, Stability Tests, Better Results, Pharmaceutical Field

References
[1] Carter, S. J. Cooper & Gunn’s Dispensing for Pharmaceutical Students. 12th edition, CBS Publishers & Distributors, India; 1987. pp-120.
[2] Shargel, L., Mutnick, A. H., Souney. P. F, Swason, L. N. (2007). Comprehensive Pharmacy Review. 6th edition. Wolters Kluwer Health (India) Pvt, LTD.
[3] Lachman, L., Lieberman, H. A., Kanig, J. L. (1987). The Theory and Practice of Industrial Pharmacy. 4th edition, Lea and Febriger, Philadelphia, U.S.A. pp- 266-267, 529.
[4] Kentish, S., Wooster, T. J., Ashokkumar, M., Balachandran, S., Mawson, R., Simons, L. (2008). The Use of Ultrasonics for nanoemulsion preparation. Innovative food science and emerging technologies. 9(2): 170-175.
[5] Mason, T. G., Wilking, J. N., Meleson, K., Chang, C. B., Graves, S. M. (2006). Nanoemulsions: formation, structure, and physical properties. Journal of Physics: Condensed Matter. 18(41): 635-666
[6] Sharma, N. K., Ahirwar, D., Jhade, D. and Gupta. S. (2009). Medicinal and pharmacological potential of Nigella sativa: A review. Ethnobotanical review. 13: 946-55.
[7] Allen Jr, L. V., Popovich, N. G., Ansel, H. C. (eds.). (2005). Ansel’s pharmaceutical dosage form and drug delivery systems. 8th edition. Lippincott Williams and Wilkins, Philadelphia, USA. pp- 409, 414.
[8] Aulton, M. E. (1990). Pharmaceutical practice. 1st Edition. Longman Singapore Publishers Pte Ltd. pp- 115.
[9] Bolton, S., Bol, C. (2005). Pharmaceutical Statistics: Practical and Clinical Applications. 4th edition. Marcel Dekker, Inc. New York. pp- 468.
[10] Smaoui, S., Hlima, H. B., Jarraya, R., Kamoun, N. G., Ellouze, R., and Damak, M. (2012). Cosmetic emulsion from virgin olive oil: Formulation and bio-physical evaluation. African Journal of Biotechnology. 11(40): 9664-9671.
[11] Libermann, H. A., Reiger, M, M. and Banker, G.S. (eds). (1998). Pharmaceutical dosage forms. Dispersed system. Volume I. Marcel Dekker Inc. Newyork and Basel. pp: 234.
[12] Becher, P. (1965). Emulsion theory and practice. 2nd edition. Reinhold, New York.
[13] Lubrizol standard test procedure (2007). Lubrizol Advanced Materials, Inc. is a wholly owned subsidiary of The Lubrizol Corporation. Available from: www.personalcare.noveon.com
Cite This Article
  • APA Style

    Shanita Zaman Smrity, A. H. M. Saifuddin, Sakina Sultana. (2016). Stability Analysis of Formulated Emulsion Containing Black Cumin (Nigella sativa) Oil. American Journal of Biomedical and Life Sciences, 4(3), 49-53. https://doi.org/10.11648/j.ajbls.20160403.15

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    ACS Style

    Shanita Zaman Smrity; A. H. M. Saifuddin; Sakina Sultana. Stability Analysis of Formulated Emulsion Containing Black Cumin (Nigella sativa) Oil. Am. J. Biomed. Life Sci. 2016, 4(3), 49-53. doi: 10.11648/j.ajbls.20160403.15

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    AMA Style

    Shanita Zaman Smrity, A. H. M. Saifuddin, Sakina Sultana. Stability Analysis of Formulated Emulsion Containing Black Cumin (Nigella sativa) Oil. Am J Biomed Life Sci. 2016;4(3):49-53. doi: 10.11648/j.ajbls.20160403.15

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  • @article{10.11648/j.ajbls.20160403.15,
      author = {Shanita Zaman Smrity and A. H. M. Saifuddin and Sakina Sultana},
      title = {Stability Analysis of Formulated Emulsion Containing Black Cumin (Nigella sativa) Oil},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {4},
      number = {3},
      pages = {49-53},
      doi = {10.11648/j.ajbls.20160403.15},
      url = {https://doi.org/10.11648/j.ajbls.20160403.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20160403.15},
      abstract = {In this present study emulsions were prepared by using black cumin oil. Dry gum method was followed to prepare emulsions formula A & B. Stability tests including organoleptic property evaluation, pH test, accelerated stability studies, water-drop test and peroxide value were determined. In case of organoleptic property evaluation emulsions showed insignificant changes and there were no variation in pH in both preparations up to 3 months. Emulsions were also undergone to different temperature effects and centrifugation at 4000 rpm, but lost the homogenous structure and separated into two phases under the effect of light and centrifugation. The study showed better results for emulsion B comparing with emulsion A. Thus our results showed that emulsion formulation B can be a good semi-solid preparation in Pharmaceutical field and food industry.},
     year = {2016}
    }
    

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  • TY  - JOUR
    T1  - Stability Analysis of Formulated Emulsion Containing Black Cumin (Nigella sativa) Oil
    AU  - Shanita Zaman Smrity
    AU  - A. H. M. Saifuddin
    AU  - Sakina Sultana
    Y1  - 2016/05/28
    PY  - 2016
    N1  - https://doi.org/10.11648/j.ajbls.20160403.15
    DO  - 10.11648/j.ajbls.20160403.15
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 49
    EP  - 53
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.20160403.15
    AB  - In this present study emulsions were prepared by using black cumin oil. Dry gum method was followed to prepare emulsions formula A & B. Stability tests including organoleptic property evaluation, pH test, accelerated stability studies, water-drop test and peroxide value were determined. In case of organoleptic property evaluation emulsions showed insignificant changes and there were no variation in pH in both preparations up to 3 months. Emulsions were also undergone to different temperature effects and centrifugation at 4000 rpm, but lost the homogenous structure and separated into two phases under the effect of light and centrifugation. The study showed better results for emulsion B comparing with emulsion A. Thus our results showed that emulsion formulation B can be a good semi-solid preparation in Pharmaceutical field and food industry.
    VL  - 4
    IS  - 3
    ER  - 

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Author Information
  • Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh

  • Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh

  • Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh

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