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Studies on Lipid Profile Levels in Hypertensive and Type 2 Diabetes Mellitus

Received: 10 February 2014     Published: 20 March 2014
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Abstract

Studies on the effect of non-hypertensive and hypertensive type 2 diabetes on lipid profile was performed to determine whether these biochemical parameters were affected in individuals associated with these disease conditions. A total of one hundred and thirty-three (133) individuals were used for these studies. Of these thirty-five (35) were established hypertensive diabetics and thirty (30) are established non-hypertensive diabetics. The established hypertensive non-diabetics were thirty-three (33) while thirty-five (35) were normal healthy individuals. The results showed that there was no significant differences (P>0.05) in the mean concentrations of cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol and glucose between hypertensive diabetics and non-hypertensive diabetics studied. The study also showed that there were no significance differences (P>0.05) in the mean levels of all the parameters measured between hypertensive diabetics and hypertensive non-diabetics subjects studied, except for serum glucose that significantly higher (P<0.05) in hypertensive diabetics. It was observed that mean concentrations of cholesterol, triglycerides, LDC-cholesterol, as well as systolic blood pressure were significantly higher (P<0.05) in hypertensive diabetics compared with normal healthy individuals. The results also show that the mean HDL-cholesterol level was significantly lower (P>0.05) in hypertensive diabetics compared with normal healthy individuals. It was also observed that the concentrations of cholesterol, triglycerides, LDL-cholesterol systolic and diastolic blood pressure were significantly higher (P>0.05) in hypertensive non diabetics individuals compared with normal healthy individuals studied. However, the glucose and pulse rate mean levels showed no significant difference (P>0.05) between hypertensive non-diabetics and normal healthy individuals.

Published in American Journal of Biomedical and Life Sciences (Volume 2, Issue 1)
DOI 10.11648/j.ajbls.20140201.15
Page(s) 28-33
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Hypertension, Type 2 Diabetics

References
[1] Mayne, DP. Plasma Lipids and Lipometenis, in: Clinical Chemistry in Diagnosis and Treatment. Sixth edition, Oxford University Press, Inco. New York; 1996.
[2] Grundy SM, Pasternak R Greenland P. (1999). Assessment of Cardiovascular Risk Factor, Assessment Equation Journal of American glucose of Cardiology. 1999; 34:1248-1359.
[3] Wilson PH, Dagostino RB, Levy D. Prediction of Coronary Heart Disease Using Risk Factor Categories. Circulations. 1998; 97;1837-1847.
[4] Harlan WR. Cardiovascular Disease Care for Women: Service Utilization, Disability Utilization, and Expenditure Survey. In: Eaker ED, Packard B, Wenaer NK, Clarkson TB, Tyroler HA’s Coronary Heart Disease in Women. 4th Ed, New York, Haymanket Doyma; 1986
[5] Harris MI, Hadden WC, Knowler WC, Bennet PH. Mevalence of Diabetus and Impaired Glucose Tolerance and Plasma Glucose levels in U.S. Population aged 20-74 years Diabetics. 1987; 36:523-523, 534.
[6] Sokolow M, Malwen BM. Coronary Disease In: Clinical Cardiology, 2nd edition, Lans Medical Publications, California; 1979
[7] Tietz NW. Lipid, Apolipopotients. In: Fundamentals of Clinical Chemistry, 6th edition, WB Saunders Company, London; 2003
[8] Alderman MH, Cohen H, Mad Haven S, Kivilann S. Serum Uric acid and Cardiovascular Disease events in Successfully Treated Hypertensive Patient. Hypertensive. 1999; 34:144-150.
[9] Bishop ML, Duben, Engelkiri, JL, Fody, EP. Carbohydrate, Diabetes mellitus. In: Clinical chemistry, Principles, Procedures, Correlations, 2nd edition, J.B. Lippincott company, 1991.
[10] Roberts WC. Preventing and Arresting Coronary Atherosileresis. American heat Journal. 1995; 130:580-597.
[11] Lehninger AL. The biosynthesis of lipids. In: Principles of Biochemistry, 2nd edition, Worth Publishers Inc, New York. 1993
[12] Garcia A, Gutiierrez JM, Fernandez S, Aparicio J, Menendez PA. Dietary Intervention in a Hypercholustero-lemic School Aged Population from Northern Spain. Journal of Revolution of Physiology. 1996; 52:49-58.
[13] Trinder P. Diagnosis of Coronary Heart Disease. Annals of Clinical Biochemistry. 1997; 6: 24.
[14] Tilkian MS, Conover BM, Tilkian GA. Clinical Implications of Laboratory Tests; 2nd edition, the C.V. mosby company, London. 1979
[15] Kaplan A, Szabo LL, Opheim, EK. Clinical interpretation and techniques, 3rd edition, Lee and Febiger, Philadelphia. 1988.
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  • APA Style

    Ajuru, Gospel, Okolonkwo, Benjamin, Okeke, et al. (2014). Studies on Lipid Profile Levels in Hypertensive and Type 2 Diabetes Mellitus. American Journal of Biomedical and Life Sciences, 2(1), 28-33. https://doi.org/10.11648/j.ajbls.20140201.15

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    ACS Style

    Ajuru; Gospel; Okolonkwo; Benjamin; Okeke, et al. Studies on Lipid Profile Levels in Hypertensive and Type 2 Diabetes Mellitus. Am. J. Biomed. Life Sci. 2014, 2(1), 28-33. doi: 10.11648/j.ajbls.20140201.15

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    AMA Style

    Ajuru, Gospel, Okolonkwo, Benjamin, Okeke, et al. Studies on Lipid Profile Levels in Hypertensive and Type 2 Diabetes Mellitus. Am J Biomed Life Sci. 2014;2(1):28-33. doi: 10.11648/j.ajbls.20140201.15

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  • @article{10.11648/j.ajbls.20140201.15,
      author = {Ajuru and Gospel and Okolonkwo and Benjamin and Okeke and Chukwubike},
      title = {Studies on Lipid Profile Levels in Hypertensive and Type 2 Diabetes Mellitus},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {2},
      number = {1},
      pages = {28-33},
      doi = {10.11648/j.ajbls.20140201.15},
      url = {https://doi.org/10.11648/j.ajbls.20140201.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20140201.15},
      abstract = {Studies on the effect of non-hypertensive and hypertensive type 2 diabetes on lipid profile was performed to determine whether these biochemical parameters were affected in individuals associated with these disease conditions. A total of one hundred and thirty-three (133) individuals were used for these studies. Of these thirty-five (35) were established hypertensive diabetics and thirty (30) are established non-hypertensive diabetics. The established hypertensive non-diabetics were thirty-three (33) while thirty-five (35) were normal healthy individuals. The results showed that there was no significant differences (P>0.05) in the mean concentrations of cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol and glucose between hypertensive diabetics and non-hypertensive diabetics studied. The study also showed that there were no significance differences (P>0.05) in the mean levels of all the parameters measured between hypertensive diabetics and hypertensive non-diabetics subjects studied, except for serum glucose that significantly higher (P0.05) in hypertensive diabetics compared with normal healthy individuals. It was also observed that the concentrations of cholesterol, triglycerides, LDL-cholesterol systolic and diastolic blood pressure were significantly higher (P>0.05) in hypertensive non diabetics individuals compared with normal healthy individuals studied. However, the glucose and pulse rate mean levels showed no significant difference (P>0.05) between hypertensive non-diabetics and normal healthy individuals.},
     year = {2014}
    }
    

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    T1  - Studies on Lipid Profile Levels in Hypertensive and Type 2 Diabetes Mellitus
    AU  - Ajuru
    AU  - Gospel
    AU  - Okolonkwo
    AU  - Benjamin
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    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
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    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.ajbls.20140201.15
    AB  - Studies on the effect of non-hypertensive and hypertensive type 2 diabetes on lipid profile was performed to determine whether these biochemical parameters were affected in individuals associated with these disease conditions. A total of one hundred and thirty-three (133) individuals were used for these studies. Of these thirty-five (35) were established hypertensive diabetics and thirty (30) are established non-hypertensive diabetics. The established hypertensive non-diabetics were thirty-three (33) while thirty-five (35) were normal healthy individuals. The results showed that there was no significant differences (P>0.05) in the mean concentrations of cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol and glucose between hypertensive diabetics and non-hypertensive diabetics studied. The study also showed that there were no significance differences (P>0.05) in the mean levels of all the parameters measured between hypertensive diabetics and hypertensive non-diabetics subjects studied, except for serum glucose that significantly higher (P0.05) in hypertensive diabetics compared with normal healthy individuals. It was also observed that the concentrations of cholesterol, triglycerides, LDL-cholesterol systolic and diastolic blood pressure were significantly higher (P>0.05) in hypertensive non diabetics individuals compared with normal healthy individuals studied. However, the glucose and pulse rate mean levels showed no significant difference (P>0.05) between hypertensive non-diabetics and normal healthy individuals.
    VL  - 2
    IS  - 1
    ER  - 

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