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The Etiology of Febrile Illnesses among Febrile Patients Attending Felegeselam Health Center, Northwest Ethiopia

Received: 7 October 2013     Published: 20 November 2013
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Abstract

The causes of acute febrile illness remain undifferentiated in many parts of the world and their burden is still challenging particularly in resource poor countries. The problem is significance especially in malaria endemic areas of tropical and sub-tropical regions. A cross sectional study was conducted during December 2011 in Northwest Ethiopia to determine the etiological agents of febrile illnesses among 398 acute febrile patients. Vein blood was collected to determine the etiological agents of febrile illnesses. The analysis of generated data revealed that the prevalence of malaria, typhoid, typhus and relapsing fever were 51.5%, 10.3%, 5% and 0%, respectively. Malaria prevalence found to be the highest among other febrile illnesses followed by typhoid and typhus. Of the malaria infections Plasmodium falciparum prevalence accounts the highest 49.75% followed by Plasmodium vivax 1.75% (n= 398). Awareness of the community about the sign and symptom of febrile illnesses were less. In addition, Proper bed net utilization was lower in rural than urban. Therefore, it is important to perform parasitological examination and serological tests simultaneously to encourage proper diagnosis and treatment of acute febrile cases especially in malaria endemic areas.

Published in American Journal of Biomedical and Life Sciences (Volume 1, Issue 3)
DOI 10.11648/j.ajbls.20130103.14
Page(s) 58-63
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2013. Published by Science Publishing Group

Keywords

Malaria, Febrile Illness, Prevalence, Awareness

References
[1] Archibald L.K, Reller L.B, "Clinical microbiology in developing countries", Emerg Infect Dissease, vol. 7, pp.302-305, 2001.
[2] Black R.E, Morris S.S, Bryce J. "Where and why are 10 million children dying every year?", The lancet, vol.361, pp. 2226-2234, 2003.
[3] Kasper M.R, Blair P.J, Touch S, Sokhal B, Yasuda C.Y, Williams M, Richards AL, Burgess T.H, Thomas WF, Putnam S.D, "Infectious Etiologies of Acute Febrile Illness among Patients Seeking Health Care in South Central Cambodia", Am. J. Trop. Med. Hygiene, vol. 86, pp. 246–253, 2012.
[4] Afifi S.K.E, Azab M.A, Youssef F.G, Sakka H.E, Wasfy M, Mansour H, Said O, Magda R, Francis M, "Hospital-based surveillance for acute febrile illness in Egypt: a focus on community-acquired bloodstream infections", Am J. Trop. Med. Hygiene, vol. 73, pp. 392–399, 2005.
[5] Lubell Y, "Likely Health Outcomes for Untreated Acute Febrile Illness in the Tropics in Decision and Economic Models: A Delphi Survey", PLoS one, vol. 6(2), 2011.
[6] Gwer S, Newton C.R.J.C, Berkley J.A, "Over-diagnosis and co-morbidity of severe malaria in African children: a Guide for Clinicians", Am. J. Trop. Med. Hygiene, 77, pp 6–13, 2007.
[7] Reyburn H, Mbakilwa H, Mwangi R, Mwerinde O, Olomi R, Drakeley C, Whitty C.J, "Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomised trial", BMJ, vol. 334, pp. 403, 2007.
[8] Animut A, Mekonnen A, Shimelis D, Epheraim A, "Febrile illness of different etiology among out patients in four health centers south western Ethiopia", JPN. journal of infect. Dissease, vol. 62, pp. 107-110, 2009.
[9] Schellenberg A, Adam J.R.M, Mshinda T, Masanja H, Kabadi H, Mukasa G, John O, Charles T, Nathan S, Wilczynska R, Mgalula K, Mbuya L, Mswia C, Manzi R, Savigny F.D.E, Schellenberg D.D, Victora C, "Effectiveness and cost of facility-based Integrated Management of Child Illness (IMCI) in Tanzania" Lancet; vol. 364, pp. 1583-1594, 2004.
[10] Koram K.A, Emolyneux M, "When Is "Malaria" Malaria? The Different Burdens of Malaria Infection, Malaria Disease and Malaria-Like Illnesses". Am. J. Trop. Med. Hygiene, vol. 77, pp. 1–5, 2007
[11] Meara O.W.P, Nkesa J.M, Steketee R, Greenwood B, "Changes in the burden of malaria in sub-Saharan Africa" Lancet Infect Disease, vol. 10, pp. 545–555, 2010.
[12] MOH: Malaria diagnosis and treatment guidelines for health workers in Ethiopia, 2nd edition: Federal Democratic republic of Ethiopia 2005. [URL: cnhde.ei.columbia.edu/files/1/1/2005]
[13] MOH: National malaria guide line 3rd edition, National malaria guide line-MOH. [URL: www.moh.gov.et/.../National/malaria/guidelines/2012]
[14] Maltha J, Gillet P, Bottieau E, Cnops L, Esbroeck MV, et al, "Evaluation of a rapid diagnostic test (CareStart™ Malaria HRP-2/pLDH (Pf/pan) Combo Test) for the diagnosis of malaria in a reference setting", Malaria Journal, vol. 9, pp. 171, 2010.
[15] Aftab R, Khurshid R, "Widal agglutination titer: a rapid serological diagnosis of typhoid fever in developing countries". Pak. J. Physiology, vol. 5, 65-76, 2009.
[16] Deressa W, Chibsa S, Olana D, "Treatment Seeking of Malaria Patients in East Shewa Zone of Oromia, Ethiopia" Ethiop. J. Health Development, vol.17, pp. 9-15, 2003.
[17] Animut A, Gebre-Michael T, Medhin G, Balkew M, Bashaye S, Seyoum A, "Assessment of distribution, knowledge and utilization of insecticide treated nets in selected malaria prone areas of Ethiopia", Ethio. J. Health Development, vol. 22, pp. 22, 268-274. 2008.
[18] Dagne G, Deressa W, "Knowledge and utilization of insecticide treated mosquito nets among freely supplied households in Wonago Woreda, Southern Ethiopia", Ethiop. J. Health Development, vol. 22, pp. 34-41, 2008.
[19] Deressa W, "Treatment-seeking behavior for febrile illness in an area of seasonal malaria transmission in rural Ethiopia", Malaria Journal, vol. 6 pp. 49, 2007.
[20] Chrispal A , Boorugu H, Gopinath K.G, Chandy S, Prakash J.A.J, Thomas E.M, Abraham A.M, Abraham O.C, "Thomas K: Acute undifferentiated febrile illness in adult hospitalized patients: the disease spectrum and diagnostic predictors: an experience from a tertiary care hospital in South India", Trop. Doctor, vol. 40, pp. 230-234, 2010.
[21] Abera B, Biadegelgen F, Bezabih B, "Prevalence of Salmonella typhi and intestinal parasites among food handlers in Bahir Dar Town, Northwest Ethiopia", Ethiop. J. Health Development, vol. 24, pp. 46-50, .2010.
[22] Ndip L.M, Bouyer D.H, Travassos D.A, Rosa P.A, Titanji V.P.K, Tesh R.B, Walker D.H, "Acute spotted fever Rickettsiosis among Febrile Patients, Cameroon", Emer. Infect. Disease, vol. 10, pp. 432–437, 2004.
[23] Kasper M.R, Blair P.J, Touch S, Sokhal B, Yasuda C.Y, Williams M, Richards A.L, Burgess T.H, Wierzba T.F, Putnam S.D, "Infectious Etiologies of Acute Febrile Illness among Patients Seeking Health Care in South-Central Cambodia", Am . J. Trop. Med. Hygiene, vol. 86, pp. 246–253, 2012.
[24] Kachur P, Schulden J, Goodman C.A, Kassala H, Farida B.E, Khatib R.A, Causer L.M, Mkikima S, Abdulla S, Bloland P.B, "Prevalence of malaria parasitemia among clients seeking treatment for fever or malaria at drug stores in rural Tanzania 2004", Trop. Med. and International Health. Vol.11, pp. 441–451, 2006.
[25] Zerihun T, Degarege A, Erko B, "Association of ABO blood group and Plasmodium falciparum malaria in Dore Bafeno Area, Southern Ethiopia", Asian Pacific Journal of Tropical Biomedicine, vol. 1, pp. 289-294, 2011.
[26] Chuks J.M, Irene K.A, "Prevalence and Management of Malaria in Ghana: A Case Study of Volta Region", African Population Studies, vol. 22(1), 2003
[27] Ashley E.A, Touab M, Ahrer M, Hutagalung R, Htun K, Luchavez J, Dureza C, Proux S, Leimanis M, Lwin M.M, Koscalova A, Comte E, Hamade P, Page A-L.N, Guerin P.J, "Evaluation of three parasite lactate dehydrogenase based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria", Malaria Journal, vol. 8, pp. 241, 2009.
[28] Asnakew K.Y, Sucharita G, Afework T.H, Dereje O.D, Hrishikesh, P.P, "Spatial analysis of malaria incidence at the village level in areas with unstable transmission in Ethiopia", Int. J. H. Geographics, vol. 8, pp. 5, 2009.
[29] Kachur P, Schulden J, Goodman C.A, Kassala H, Farida B.E, Khatib R.A, Causer L.M, Mkikima S, Abdulla S, Bloland P.B, "Prevalence of malaria parasitemia among clients seeking treatment for fever or malaria at drug stores in rural Tanzania 2004", Tropical Medicine and International Health, vol. 11, pp. 441-451, 2006.
[30] Clarke S, Brooker S, Kiambo J, Njau N, Estambale E.B, Muchiri E, Magnussen P, "Malaria morbidity among school children living in two areas of contrasting transmission in western Kenya", Am. J. Trop. Med. Hygiene, vol. 71 pp. 732–738, 2004.
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  • APA Style

    Hailu Tadesse, Kebede Tadesse. (2013). The Etiology of Febrile Illnesses among Febrile Patients Attending Felegeselam Health Center, Northwest Ethiopia. American Journal of Biomedical and Life Sciences, 1(3), 58-63. https://doi.org/10.11648/j.ajbls.20130103.14

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    ACS Style

    Hailu Tadesse; Kebede Tadesse. The Etiology of Febrile Illnesses among Febrile Patients Attending Felegeselam Health Center, Northwest Ethiopia. Am. J. Biomed. Life Sci. 2013, 1(3), 58-63. doi: 10.11648/j.ajbls.20130103.14

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    AMA Style

    Hailu Tadesse, Kebede Tadesse. The Etiology of Febrile Illnesses among Febrile Patients Attending Felegeselam Health Center, Northwest Ethiopia. Am J Biomed Life Sci. 2013;1(3):58-63. doi: 10.11648/j.ajbls.20130103.14

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  • @article{10.11648/j.ajbls.20130103.14,
      author = {Hailu Tadesse and Kebede Tadesse},
      title = {The Etiology of Febrile Illnesses among Febrile Patients Attending Felegeselam Health Center, Northwest Ethiopia},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {1},
      number = {3},
      pages = {58-63},
      doi = {10.11648/j.ajbls.20130103.14},
      url = {https://doi.org/10.11648/j.ajbls.20130103.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20130103.14},
      abstract = {The causes of acute febrile illness remain undifferentiated in many parts of the world and their burden is still challenging particularly in resource poor countries. The problem is significance especially in malaria endemic areas of tropical and sub-tropical regions. A cross sectional study was conducted during December 2011 in Northwest Ethiopia to determine the etiological agents of febrile illnesses among 398 acute febrile patients. Vein blood was collected to determine the etiological agents of febrile illnesses. The analysis of generated data revealed that the prevalence of  malaria, typhoid, typhus and relapsing fever were 51.5%, 10.3%, 5% and 0%, respectively. Malaria prevalence found to be the highest among other febrile illnesses followed by typhoid and typhus. Of the malaria infections Plasmodium falciparum prevalence accounts the highest 49.75% followed by Plasmodium vivax 1.75% (n= 398). Awareness of the community about the sign and symptom of febrile illnesses were less. In addition, Proper bed net utilization was lower in rural than urban. Therefore, it is important to perform parasitological examination and serological tests simultaneously to encourage proper diagnosis and treatment of acute febrile cases especially in malaria endemic areas.},
     year = {2013}
    }
    

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    AU  - Hailu Tadesse
    AU  - Kebede Tadesse
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    DO  - 10.11648/j.ajbls.20130103.14
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
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    AB  - The causes of acute febrile illness remain undifferentiated in many parts of the world and their burden is still challenging particularly in resource poor countries. The problem is significance especially in malaria endemic areas of tropical and sub-tropical regions. A cross sectional study was conducted during December 2011 in Northwest Ethiopia to determine the etiological agents of febrile illnesses among 398 acute febrile patients. Vein blood was collected to determine the etiological agents of febrile illnesses. The analysis of generated data revealed that the prevalence of  malaria, typhoid, typhus and relapsing fever were 51.5%, 10.3%, 5% and 0%, respectively. Malaria prevalence found to be the highest among other febrile illnesses followed by typhoid and typhus. Of the malaria infections Plasmodium falciparum prevalence accounts the highest 49.75% followed by Plasmodium vivax 1.75% (n= 398). Awareness of the community about the sign and symptom of febrile illnesses were less. In addition, Proper bed net utilization was lower in rural than urban. Therefore, it is important to perform parasitological examination and serological tests simultaneously to encourage proper diagnosis and treatment of acute febrile cases especially in malaria endemic areas.
    VL  - 1
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Author Information
  • Department of Microbiology, Immunology and Parasitology

  • Department of Microbiology, Immunology and Parasitology

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