The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats

Areshidze David; Timchenko Luydmila; Кozlova Maria

doi:doi:10.11648/j.ajbls.20130101.16

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The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats

Areshidze David, Timchenko Luydmila, Кozlova Maria

Published in American Journal of Biomedical and Life Sciences (Volume 1, Issue 1)

Received: 26 May 2013 Published: 30 July 2013

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Abstract

Investigation of the influence of the enzymatic hydrolyzate of Chlorophytum comosumthe first on the liver of rats at its toxic damage showed that the substrate has expressed a pronounced hepatoprotective effect. Under its influence in the rat liver morphological changes induced by CCl4 are much less pronounced than in the controls. There are also less significant deviations from normal levels of ALT, AST and bilirubin. Information analysis of the state of the organ indicates that the level of adaptation and regeneration opportunities of the liver of rats treated with an enzymatic hydrolyzate of Chlorophytum comosum is significantly higher than that of the liver of rats with experimental toxic liver damage without the use of tested substrate.

Published in	American Journal of Biomedical and Life Sciences (Volume 1, Issue 1)
DOI	10.11648/j.ajbls.20130101.16
Page(s)	32-36
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2013. Published by Science Publishing Group

Keywords

Liver, Hydrolizate, Hepatocyte, Chlorophytum Comosum

References

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[2]	S.E. Afton, B. Catron and J.A. Caruso,"Elucidating the selenium and arsenic metabolic pathways following exposure to the non-hyperaccumulatingChlorophytum comosum, spider plant", Journal of Experimental Botany 2009, vol. 60; 4, pp.1289-1297.
[3]	G.G.Avtandilov 2008.Medical Morphometry [in Russian]. Moscow:Meditsina,. pp.298.
[4]	M. Giese, U. Bauer-Doranth, S.Langebartels, and H. Sandermann" Detoxification of Formaldehyde by the Spider Plant (Chlorophytum comosum L.) and by Soybean (Glycine max L.) Cell-Suspension Cultures", Plant Physiology1994, vol. 4, pp. 1301-1309.
[5]	A.J.Haagen-Smit, E.F. Darley, M.Zaitlin, H. Hull and W.Noble "Investigation on injury to plants from air pollution in the Los Angeles area", Plant Physiology, 1952; vol. 27, pp. 18-34.
[6]	C.P. Kala, B.S.Dhyani and B.S.Sajwan. "Developing the medicinal plants sector in northern India: challenges and opportunities", Journal of Ethnobiology and Ethnomedicine. 2006,vol. 6, pp. 32-38.
[7]	M.D. Logsdon, Jr. Meyn,and P.C.Besa. "Apoptosis and the Bcl–2 gene family: patterns of expression and prognostic value in stage I and II follicular center lymphoma?",Int J RadiatOncolBiolPhys 1999,vol.44, pp. 19-29.
[8]	H. Matsushita, H.Kuwabara, H. Matsushita, S. Ishikawa and M. Mochizuki. "Apoptosis Induced in Human Cell Lines by a Butanol Extract from Chlorophytum comosum", Roots Journal of Health Science, 2005,vol. 51, pp. 341-345.
[9]	M. Thakur, S. Bhangava and V. Dixit "Immunomodulatory Activity of Chlorophytum borivilianum", Sant. Evid Based Complement Alternative Medicine, 2007, vol. 4, pp. 419-423.
[10]	R.A. Wood, R. Orwell, M.D. Burchett, J. Tarran and S.K. Brown. "Absorption of organic compounds in indoor air by commonly used indoor plants", Proceedings of Healthy Buildings,2000, vol. 2, pp. 125-130.

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Areshidze David, Timchenko Luydmila, Кozlova Maria. (2013). The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats. American Journal of Biomedical and Life Sciences, 1(1), 32-36. https://doi.org/10.11648/j.ajbls.20130101.16

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ACS Style

Areshidze David; Timchenko Luydmila; Кozlova Maria. The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats. Am. J. Biomed. Life Sci. 2013, 1(1), 32-36. doi: 10.11648/j.ajbls.20130101.16

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AMA Style

Areshidze David, Timchenko Luydmila, Кozlova Maria. The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats. Am J Biomed Life Sci. 2013;1(1):32-36. doi: 10.11648/j.ajbls.20130101.16

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@article{10.11648/j.ajbls.20130101.16,
  author = {Areshidze David and Timchenko Luydmila and Кozlova Maria},
  title = {The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {1},
  number = {1},
  pages = {32-36},
  doi = {10.11648/j.ajbls.20130101.16},
  url = {https://doi.org/10.11648/j.ajbls.20130101.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20130101.16},
  abstract = {Investigation of the influence of the enzymatic hydrolyzate of Chlorophytum comosumthe first on the liver of rats at its toxic damage showed that the substrate has expressed a pronounced hepatoprotective effect. Under its influence in the rat liver morphological changes induced by CCl4 are much less pronounced than in the controls. There are also less significant deviations from normal levels of ALT, AST and bilirubin. Information analysis of the state of the organ indicates that the level of adaptation and regeneration opportunities of the liver of rats treated with an enzymatic hydrolyzate of Chlorophytum comosum is significantly higher than that of the liver of rats with experimental toxic liver damage without the use of tested substrate.},
 year = {2013}
}

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TY  - JOUR
T1  - The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats
AU  - Areshidze David
AU  - Timchenko Luydmila
AU  - Кozlova Maria
Y1  - 2013/07/30
PY  - 2013
N1  - https://doi.org/10.11648/j.ajbls.20130101.16
DO  - 10.11648/j.ajbls.20130101.16
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 32
EP  - 36
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20130101.16
AB  - Investigation of the influence of the enzymatic hydrolyzate of Chlorophytum comosumthe first on the liver of rats at its toxic damage showed that the substrate has expressed a pronounced hepatoprotective effect. Under its influence in the rat liver morphological changes induced by CCl4 are much less pronounced than in the controls. There are also less significant deviations from normal levels of ALT, AST and bilirubin. Information analysis of the state of the organ indicates that the level of adaptation and regeneration opportunities of the liver of rats treated with an enzymatic hydrolyzate of Chlorophytum comosum is significantly higher than that of the liver of rats with experimental toxic liver damage without the use of tested substrate.
VL  - 1
IS  - 1
ER  -

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Author Information

Areshidze David

Center of Cell Biology and Applied Biotechnology, Moscow State Regional University, Moscow, Russian federation
Timchenko Luydmila

Institute of the living systems of the North Caucasus Federal University, Stavropol, Russian federation
Кozlova Maria

Center of Cell Biology and Applied Biotechnology, Moscow State Regional University, Moscow, Russian federation

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APA Style

Areshidze David, Timchenko Luydmila, Кozlova Maria. (2013). The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats. American Journal of Biomedical and Life Sciences, 1(1), 32-36. https://doi.org/10.11648/j.ajbls.20130101.16

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ACS Style

Areshidze David; Timchenko Luydmila; Кozlova Maria. The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats. Am. J. Biomed. Life Sci. 2013, 1(1), 32-36. doi: 10.11648/j.ajbls.20130101.16

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AMA Style

Areshidze David, Timchenko Luydmila, Кozlova Maria. The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats. Am J Biomed Life Sci. 2013;1(1):32-36. doi: 10.11648/j.ajbls.20130101.16

Copy | Download

@article{10.11648/j.ajbls.20130101.16,
  author = {Areshidze David and Timchenko Luydmila and Кozlova Maria},
  title = {The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {1},
  number = {1},
  pages = {32-36},
  doi = {10.11648/j.ajbls.20130101.16},
  url = {https://doi.org/10.11648/j.ajbls.20130101.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20130101.16},
  abstract = {Investigation of the influence of the enzymatic hydrolyzate of Chlorophytum comosumthe first on the liver of rats at its toxic damage showed that the substrate has expressed a pronounced hepatoprotective effect. Under its influence in the rat liver morphological changes induced by CCl4 are much less pronounced than in the controls. There are also less significant deviations from normal levels of ALT, AST and bilirubin. Information analysis of the state of the organ indicates that the level of adaptation and regeneration opportunities of the liver of rats treated with an enzymatic hydrolyzate of Chlorophytum comosum is significantly higher than that of the liver of rats with experimental toxic liver damage without the use of tested substrate.},
 year = {2013}
}

Copy | Download

TY  - JOUR
T1  - The Use of Enzymatic Hydrolyzate of Chlorophytum Comosum with Experimental Toxic Liver Damage in Rats
AU  - Areshidze David
AU  - Timchenko Luydmila
AU  - Кozlova Maria
Y1  - 2013/07/30
PY  - 2013
N1  - https://doi.org/10.11648/j.ajbls.20130101.16
DO  - 10.11648/j.ajbls.20130101.16
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 32
EP  - 36
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20130101.16
AB  - Investigation of the influence of the enzymatic hydrolyzate of Chlorophytum comosumthe first on the liver of rats at its toxic damage showed that the substrate has expressed a pronounced hepatoprotective effect. Under its influence in the rat liver morphological changes induced by CCl4 are much less pronounced than in the controls. There are also less significant deviations from normal levels of ALT, AST and bilirubin. Information analysis of the state of the organ indicates that the level of adaptation and regeneration opportunities of the liver of rats treated with an enzymatic hydrolyzate of Chlorophytum comosum is significantly higher than that of the liver of rats with experimental toxic liver damage without the use of tested substrate.
VL  - 1
IS  - 1
ER  -

Copy | Download