Research Article
Evaluation of the Molluscicidal Activity of Aqueous and Ethanolic Extracts of the Neorautanenia Mitis Plant Against Snail Intermediate Hosts of Bilharziasis in the Laboratory
Jean Jacques Mashimango Bagalwa*,
Prince Kilamwaka Nshombo,
Antoine Kaguku Nfundiko,
Katcho Karume
Issue:
Volume 11, Issue 6, December 2025
Pages:
113-118
Received:
20 October 2025
Accepted:
31 October 2025
Published:
11 December 2025
Abstract: Schistosomiasis remains a major public health problem in tropical countries and especially in DR Congo. One of the main preventive measures against trematode infection is the control of the disease vector population through the use of molluscicides. The objective of this work is focused on the fight against bilharzia intermediate host snails using extracts of the Neorautanenia mitis plant from the East of the Democratic Republic of Congo against the snails Biomphalaria pfeifferi intermediate host of bilharziasis. For the identification of the different characteristics of the plant, we used phytochemical tests based on color or precipitation reactions and a test of molluscicidal activities to know the lethal concentrations of the extracts were carried out. Analysis of the plant Neorautanenia mitis shows that this plant is pharmacologically active against snail intermediate hosts of bilharziasis. It contains phenol, terpene and saponin which are recognized as molluscicidal and insecticidal substances. The mortality rate is greater than 50% at a concentration of up to 0.002mg/L of the crude extracts in ethanol of this plant. This plant is very poisonous than these other plants. But the responsible substance is not yet well determined and deserves very detailed studies of the extraction of the different responsible substances and their tests on molluscs before determining the structure of this substance.
Abstract: Schistosomiasis remains a major public health problem in tropical countries and especially in DR Congo. One of the main preventive measures against trematode infection is the control of the disease vector population through the use of molluscicides. The objective of this work is focused on the fight against bilharzia intermediate host snails using ...
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Research Article
Analytical Study of Some Drug Brands Used to Treat Stomach Acidity
Aisha Alfituri Benjuma*
,
Rabia Omar Eshkourfu,
Najat Faraj Abu Naji,
Ruwaida Muammar Al-Rabshi
Issue:
Volume 11, Issue 6, December 2025
Pages:
119-125
Received:
12 August 2025
Accepted:
25 August 2025
Published:
24 December 2025
Abstract: This study is predicated on the assessment of the acid-neutralizing capacity of five distinct commercial brands of antacid. Antacids are prevalent substances utilized by individuals experiencing heightened gastric acidity, owing to their widespread availability in pharmacies. Consequently, this investigation concentrated on several brands of antacid medications, which function as weak bases that neutralize excess stomach acidity, thereby elevating the pH. The quantity of acid neutralized by each antacid was determined through back titration. The acid-neutralizing capacities of the brands were ranked as follows: A > B > E > D > C. The pH of the acid was measured after being heated to a temperature of 37°C, followed by the addition of the antacid, with a subsequent observation period of five minutes post-addition. The results regarding the impact of the antacids on acid pH were recorded as 6.95 for sample A, 6.74 for sample B, 4.58 for brand C, 1.76 for sample E, and 1.73 for sample D. An analysis of the findings indicates that sample A exhibits the highest neutralizing capacity (NC), whereas sample C demonstrates a significantly lower value of neutralizing capacity (NC).
Abstract: This study is predicated on the assessment of the acid-neutralizing capacity of five distinct commercial brands of antacid. Antacids are prevalent substances utilized by individuals experiencing heightened gastric acidity, owing to their widespread availability in pharmacies. Consequently, this investigation concentrated on several brands of antaci...
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