Abstract: Several factors affect seminal fluid indices, these factors impair male fertility either by exerting a gonadotoxic effect on the testicles, altering hypo-thalamic-pituitary-gonadal axis, impairing ejaculation and erectile function or by decreasing libido. The Study aim to assess the effects of some adverse socio-dermographic factors on seminal parameters of infertile couples. Three hundred and nine (309) male partners of infertile couples were recruited from five different fertility centers in Ilorin, Kwara state Nigeria using multi-stage sampling technique. Those with abnormal seminal fluid indices represented the study arm while those with normal semen indices represented the control arm for the study. Seminal fluid analysis was conducted on each participant and compared with World Health Organization reference for normal semen parameters. The results showed that male partners of infertile couples with abnormal seminal fluid indices had increased pattern of risky sexual behavior, with more numbers of both current sexual partners and life-time sexual partners, in addition to history of alcohol intake and cigarette smoking. (All P < 0.05). However, no statistical significant association was obtained with the amount of alcohol use, number of cigarette smoked and the use of native medication. Risky sexual behaviours, alcohol intake and cigarette smoking still remain important risk factors for abnormal seminal fluid indices. Thus, it is important to re-educate and enlighten the populace on the risk posed by these adverse social factors.Abstract: Several factors affect seminal fluid indices, these factors impair male fertility either by exerting a gonadotoxic effect on the testicles, altering hypo-thalamic-pituitary-gonadal axis, impairing ejaculation and erectile function or by decreasing libido. The Study aim to assess the effects of some adverse socio-dermographic factors on seminal para...Show More