A novel mixed ligand complex of the type [M(FU)2A2] where M is Ni(II), FU is furfuralurea and A is thiourea was synthesized, characterized by solubility test, melting point, conductivity measurement, infrared and UV/Vis spectroscopy. The mixed ligand complex of the Ni II was also tested against Proteus mirabilis, Staphlococus aureus, E. coli, Klebsiella pneumonia and Pseudomonas aeriginosa. The in vitro evaluation of the biological studies of the mixed ligand complex showed greater activity against Proteus mirabilis and Klebsiella pneumonia at 60 ug/ml/disc with the minimum zone of inhibition of 13mm and 14mm respectively. The conductivity measurement revealed that the complex is a non electrolyte. The different shade of colour of the complex from the ligand, the shift of the band of the carbonyl functional group to a lower wavelength are evidences of coordination between the metal and the ligands. An octahedral geometry was suggested for the complex. The solubility test shows that the complex is soluble in methanol and dimethylsulphoxide.
Published in | World Journal of Applied Chemistry (Volume 1, Issue 1) |
DOI | 10.11648/j.wjac.20160101.14 |
Page(s) | 22-25 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2016. Published by Science Publishing Group |
Nickel, Mixed Ligand Complex, Antimicrobial, Furfuralurea, Coordination Compounds
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APA Style
Idoko Owoicho, Emmanuel Stella, Abubakar Salisu, Thomas Sunday Asuquo. (2016). Synthesis, Characterisation and Biological Activity of Mixed Ligand Complex of Ni(II) with Furfuralurea and Thiourea. World Journal of Applied Chemistry, 1(1), 22-25. https://doi.org/10.11648/j.wjac.20160101.14
ACS Style
Idoko Owoicho; Emmanuel Stella; Abubakar Salisu; Thomas Sunday Asuquo. Synthesis, Characterisation and Biological Activity of Mixed Ligand Complex of Ni(II) with Furfuralurea and Thiourea. World J. Appl. Chem. 2016, 1(1), 22-25. doi: 10.11648/j.wjac.20160101.14
@article{10.11648/j.wjac.20160101.14, author = {Idoko Owoicho and Emmanuel Stella and Abubakar Salisu and Thomas Sunday Asuquo}, title = {Synthesis, Characterisation and Biological Activity of Mixed Ligand Complex of Ni(II) with Furfuralurea and Thiourea}, journal = {World Journal of Applied Chemistry}, volume = {1}, number = {1}, pages = {22-25}, doi = {10.11648/j.wjac.20160101.14}, url = {https://doi.org/10.11648/j.wjac.20160101.14}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjac.20160101.14}, abstract = {A novel mixed ligand complex of the type [M(FU)2A2] where M is Ni(II), FU is furfuralurea and A is thiourea was synthesized, characterized by solubility test, melting point, conductivity measurement, infrared and UV/Vis spectroscopy. The mixed ligand complex of the Ni II was also tested against Proteus mirabilis, Staphlococus aureus, E. coli, Klebsiella pneumonia and Pseudomonas aeriginosa. The in vitro evaluation of the biological studies of the mixed ligand complex showed greater activity against Proteus mirabilis and Klebsiella pneumonia at 60 ug/ml/disc with the minimum zone of inhibition of 13mm and 14mm respectively. The conductivity measurement revealed that the complex is a non electrolyte. The different shade of colour of the complex from the ligand, the shift of the band of the carbonyl functional group to a lower wavelength are evidences of coordination between the metal and the ligands. An octahedral geometry was suggested for the complex. The solubility test shows that the complex is soluble in methanol and dimethylsulphoxide.}, year = {2016} }
TY - JOUR T1 - Synthesis, Characterisation and Biological Activity of Mixed Ligand Complex of Ni(II) with Furfuralurea and Thiourea AU - Idoko Owoicho AU - Emmanuel Stella AU - Abubakar Salisu AU - Thomas Sunday Asuquo Y1 - 2016/11/23 PY - 2016 N1 - https://doi.org/10.11648/j.wjac.20160101.14 DO - 10.11648/j.wjac.20160101.14 T2 - World Journal of Applied Chemistry JF - World Journal of Applied Chemistry JO - World Journal of Applied Chemistry SP - 22 EP - 25 PB - Science Publishing Group SN - 2637-5982 UR - https://doi.org/10.11648/j.wjac.20160101.14 AB - A novel mixed ligand complex of the type [M(FU)2A2] where M is Ni(II), FU is furfuralurea and A is thiourea was synthesized, characterized by solubility test, melting point, conductivity measurement, infrared and UV/Vis spectroscopy. The mixed ligand complex of the Ni II was also tested against Proteus mirabilis, Staphlococus aureus, E. coli, Klebsiella pneumonia and Pseudomonas aeriginosa. The in vitro evaluation of the biological studies of the mixed ligand complex showed greater activity against Proteus mirabilis and Klebsiella pneumonia at 60 ug/ml/disc with the minimum zone of inhibition of 13mm and 14mm respectively. The conductivity measurement revealed that the complex is a non electrolyte. The different shade of colour of the complex from the ligand, the shift of the band of the carbonyl functional group to a lower wavelength are evidences of coordination between the metal and the ligands. An octahedral geometry was suggested for the complex. The solubility test shows that the complex is soluble in methanol and dimethylsulphoxide. VL - 1 IS - 1 ER -