The Correlation Between <i>Helicobacter pylori</i> SeroPositive Patients and Throat Infection

Hiba Orsud; Ahmed Elmontaser Omer Mergani; Suliman Elsanousi

doi:doi:10.11648/j.plm.20210502.11

| Peer-Reviewed

The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection

Hiba Orsud, Ahmed Elmontaser Omer Mergani, Suliman Elsanousi

Published in Pathology and Laboratory Medicine (Volume 5, Issue 2)

Received: 4 November 2020 Accepted: 16 November 2020 Published: 9 July 2021

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Heliocobacter pylori besides being the cause of chronic gastritis it was shown be implicated in various extra gastric manifestation. Gastric juice infected with H. pylori might have important role in upper respiratory tract. However it has not been elucidated. Therefore this study aim to clarify whether H. pylori play a role in the etiology and pathogenesis of throat infection. 307 volunteers were participated in this study. Throat swabs from tonsils and oropharynx were collected, conventional bacteriological methods were applied for identification of pathogenic bacteria, followed by PCR confirmation. Along with, serum sample were collected for determination of anti-H. pylori IgG titer by quantitative ELISA method. Prior ICT antibody-based screening test were performed. Simultaneously questionnaire data form from our participants were collected for statistical analysis. This study was designed as case control study. From throat swabs Streptococcus pyogenes was the most common in our isolates. The mean of IgG antibody titer was 95.21 RU/ml, the positive samples for IgG was quite 88.2%. Clinical respiratory symptoms were observed only in 9.7% of participants in this study 89% of them confirmed with H. pylori. Statistical data showed very high significant correlation between pathogenic bacteria S. pyogenes and H. pylori infection.

Published in	Pathology and Laboratory Medicine (Volume 5, Issue 2)
DOI	10.11648/j.plm.20210502.11
Page(s)	19-25
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection

References

[1]	Mastrandrea pl., Rappelli, P., Cappuccinelli P. 2005. Brucella abortus infection acquired in microbiology laboratories. J. clin. Microbial., 38.
[2]	Corbel MJ. 2006. Brucellosis in Humans and Animals. World Health Organization, pp. 12-79.
[3]	Bang B., 1897. The etiology of epizootic abortion. J. Comp. Path. Therap., 10: 125-149.
[4]	Craig, CF., 1903. Malta Fever: Its occurrence in the United States Army, with a review of the literature. Amer J Med Sci., 125: 105-115.
[5]	Blood, D. C., Radostits, M. and Henderson, J. A., 1983. veterinary Medicine. 6^th edition, Bailliere Tindall. London. pp. 677–696.
[6]	OIE Terrestrial Manual. 2009. Bovine Brucellosis: Brucella abortus. Institute for international cooperation in animal biology and OIE collaborating center, Paris, France.
[7]	Bagheri Nejad, R., Krecek, R. C., Khalaf, O. H., Hailat, N. and Arenas-Gamboa, A. M., 2020. Brucellosis in the Middle East: Current situation and a pathway forward. PLOS Neglected Tropical Diseases, 14 (5), p. e0008071.
[8]	Simpson, R. J. S. 1908. Malta fever from the Blue Nile. Journal of Roy Army Med. Corps., 11: 593. (Cited in Symposium on Animal brucellosis in the Sudan, 1987).
[9]	Hasseb, M. A. (1950). Undulant fever in the Sudan. Sud. J. Med., 53: 241.
[10]	Angara T. E., Ismail A. A. A, Ibrahim A. M., Osman S. Z., 2016 Assessment Of The Economic Losses Due To Bovine Brucellosis In Khartoum State, Sudan International Journal of Technical Research and Applications: Volume 4, Issue 2, PP. 85-9.
[11]	Farina, R., 1985. Current serological methods in B. melitensis diagnosis. Brucella melitensis. CEC Seminar, Brussels. 32: 139-146.
[12]	Solanki, S. and Devi, D. 2020. Epidemiology and Diagnosis of Brucellosis in Large Ruminants. Journal homepage: http://www. ijcmas. com, 9 (10), p. 2020.
[13]	Rigueira, L. L., de Souza Vilanova, L. F. L., Perecmaniss, S., Vieira, Y. C., Soares, P. M. and de Souza, P. G., 2019. Epidemiological study of swine brucellosis in household farms in Federal District of Brazil. Acta Veterinaria Brasilica, 13 (2).
[14]	Baum M., Zamir O., Bergman-Rios R, Katz E, Beider Z, Cohen A and Banai M., 1995. Comparative evaluation of microagglutination test and serum agglutination test as supplementary diagnostic methods for brucellosis. J. Clin. Microbiol. vol. 33 no. 8 2166-2170.
[15]	Greiner m, verloo d, de massis f. 2009. meta-analytical equivalence studies on diagnostic tests for bovine brucellosis allowing assessment of a test against a group of comparative tests. Prev vet med.; 92: 373-81.
[16]	McGiven JA, Tucker JD, Perrett LL, Stack JA, Brew SD, Macmillan AP. 2003. validation of FPA and cELISA for the detection of antibodies to brucella abortus in cattle sera and comparison to SAT CFT, and iELISA. J immunol methods.; 278: 171-8.
[17]	Padilla Poester F, Nielsen K, Ernesto Samartino L, Ling Yu W, 2010. Diagnosis of brucellosis. The Open Veterinary Science Journal.; 4 (1).
[18]	Carlsson, H., Hurvell, B., Lindberg, A., 1976, Enzyme-linked immunosorbent assay (ELISA) for titration of antibodies against Brucella abortus and Yersinia enterocolitic. Acta Pathol. Microbiol. Scand. 84 C, 168-176.
[19]	Zriba, S., Garcia-Gonzalez, D. G., Khalaf, O. H., Wheeler, L., Chaki, S. P., Rice-Ficht, A., Ficht, T. A. and Arenas-Gamboa, A. M., 2019. Vaccine safety studies of Brucella abortus S19 and S19ΔvjbR in pregnant swine. Vaccine: X, 3, p. 100041.
[20]	Shimi, A. and Tabatabayi, A. H., 1981. pathological, bacteriological and serological responses of ewes experimentally infected with Brucella melitensis. Bulletin office International des Epizooties, 93: 1411-1422.
[21]	Voller, A., Bidwell, D. E. and Bartlett, A. 1980. Enzyme Linked immunosorbent assay on manual of clinical immunology Rose, N and Friedman, H, Washington, D. C, Am. soc. of Micro pp 359_371.
[22]	Salman A. M. A. and El Nasri H. A., 2012; Evaluation of four serological tests to detect prevalence of bovine brucellosis in Khartoum State journal of Cell and Animal Biology Vol. 6 (9), pp. 140-143.
[23]	Angara, T- E. E.; Ismail. A. A. A.; Agab. H. & Saeed, N. M, 2009. Seroprevalence of Bovine brucellosis in Kuku dairy Scheme. Sudan J. Veterinary. Science &. Animal. Husbundary. 48 (1 & 2): pp. 27-35.
[24]	Chachra D., Saxena H. M., Kaur G. and Chandra M., 2009, Comparative efficacy of Rose Bengal plate test, standard tube agglutination test and Dot ELISA in immunological detection of antibodies to Brucella abortus in sera Journal of Bacteriology Research Vol. 1 (3), pp. 030-033.

Cite This Article

Plain Text BibTeX RIS

APA Style

Hiba Orsud, Ahmed Elmontaser Omer Mergani, Suliman Elsanousi. (2021). The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection. Pathology and Laboratory Medicine, 5(2), 19-25. https://doi.org/10.11648/j.plm.20210502.11

Copy | Download

ACS Style

Hiba Orsud; Ahmed Elmontaser Omer Mergani; Suliman Elsanousi. The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection. Pathol. Lab. Med. 2021, 5(2), 19-25. doi: 10.11648/j.plm.20210502.11

Copy | Download

AMA Style

Hiba Orsud, Ahmed Elmontaser Omer Mergani, Suliman Elsanousi. The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection. Pathol Lab Med. 2021;5(2):19-25. doi: 10.11648/j.plm.20210502.11

Copy | Download

@article{10.11648/j.plm.20210502.11,
  author = {Hiba Orsud and Ahmed Elmontaser Omer Mergani and Suliman Elsanousi},
  title = {The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection},
  journal = {Pathology and Laboratory Medicine},
  volume = {5},
  number = {2},
  pages = {19-25},
  doi = {10.11648/j.plm.20210502.11},
  url = {https://doi.org/10.11648/j.plm.20210502.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plm.20210502.11},
  abstract = {Heliocobacter pylori besides being the cause of chronic gastritis it was shown be implicated in various extra gastric manifestation. Gastric juice infected with H. pylori might have important role in upper respiratory tract. However it has not been elucidated. Therefore this study aim to clarify whether H. pylori play a role in the etiology and pathogenesis of throat infection. 307 volunteers were participated in this study. Throat swabs from tonsils and oropharynx were collected, conventional bacteriological methods were applied for identification of pathogenic bacteria, followed by PCR confirmation. Along with, serum sample were collected for determination of anti-H. pylori IgG titer by quantitative ELISA method. Prior ICT antibody-based screening test were performed. Simultaneously questionnaire data form from our participants were collected for statistical analysis. This study was designed as case control study. From throat swabs Streptococcus pyogenes was the most common in our isolates. The mean of IgG antibody titer was 95.21 RU/ml, the positive samples for IgG was quite 88.2%. Clinical respiratory symptoms were observed only in 9.7% of participants in this study 89% of them confirmed with H. pylori. Statistical data showed very high significant correlation between pathogenic bacteria S. pyogenes and H. pylori infection.},
 year = {2021}
}

Copy | Download

TY - JOUR
T1 - The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection
AU - Hiba Orsud
AU - Ahmed Elmontaser Omer Mergani
AU - Suliman Elsanousi
Y1 - 2021/07/09
PY - 2021
N1 - https://doi.org/10.11648/j.plm.20210502.11
DO - 10.11648/j.plm.20210502.11
T2 - Pathology and Laboratory Medicine
JF - Pathology and Laboratory Medicine
JO - Pathology and Laboratory Medicine
SP - 19
EP - 25
PB - Science Publishing Group
SN - 2640-4478
UR - https://doi.org/10.11648/j.plm.20210502.11
AB - Heliocobacter pylori besides being the cause of chronic gastritis it was shown be implicated in various extra gastric manifestation. Gastric juice infected with H. pylori might have important role in upper respiratory tract. However it has not been elucidated. Therefore this study aim to clarify whether H. pylori play a role in the etiology and pathogenesis of throat infection. 307 volunteers were participated in this study. Throat swabs from tonsils and oropharynx were collected, conventional bacteriological methods were applied for identification of pathogenic bacteria, followed by PCR confirmation. Along with, serum sample were collected for determination of anti-H. pylori IgG titer by quantitative ELISA method. Prior ICT antibody-based screening test were performed. Simultaneously questionnaire data form from our participants were collected for statistical analysis. This study was designed as case control study. From throat swabs Streptococcus pyogenes was the most common in our isolates. The mean of IgG antibody titer was 95.21 RU/ml, the positive samples for IgG was quite 88.2%. Clinical respiratory symptoms were observed only in 9.7% of participants in this study 89% of them confirmed with H. pylori. Statistical data showed very high significant correlation between pathogenic bacteria S. pyogenes and H. pylori infection.
VL - 5
IS - 2
ER -

Copy | Download

Author Information

Hiba Orsud

Department of Microbiology, Faculty of Veterinary Medicine, University of Khartoum, Khartoum North, Sudan
Ahmed Elmontaser Omer Mergani

Department of Microbiology, Faculty of Veterinary Medicine, University of Khartoum, Khartoum North, Sudan
Suliman Elsanousi

Department of Microbiology, Faculty of Veterinary Medicine, University of Khartoum, Khartoum North, Sudan

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Hiba Orsud, Ahmed Elmontaser Omer Mergani, Suliman Elsanousi. (2021). The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection. Pathology and Laboratory Medicine, 5(2), 19-25. https://doi.org/10.11648/j.plm.20210502.11

Copy | Download

ACS Style

Hiba Orsud; Ahmed Elmontaser Omer Mergani; Suliman Elsanousi. The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection. Pathol. Lab. Med. 2021, 5(2), 19-25. doi: 10.11648/j.plm.20210502.11

Copy | Download

AMA Style

Hiba Orsud, Ahmed Elmontaser Omer Mergani, Suliman Elsanousi. The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection. Pathol Lab Med. 2021;5(2):19-25. doi: 10.11648/j.plm.20210502.11

Copy | Download

@article{10.11648/j.plm.20210502.11,
  author = {Hiba Orsud and Ahmed Elmontaser Omer Mergani and Suliman Elsanousi},
  title = {The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection},
  journal = {Pathology and Laboratory Medicine},
  volume = {5},
  number = {2},
  pages = {19-25},
  doi = {10.11648/j.plm.20210502.11},
  url = {https://doi.org/10.11648/j.plm.20210502.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plm.20210502.11},
  abstract = {Heliocobacter pylori besides being the cause of chronic gastritis it was shown be implicated in various extra gastric manifestation. Gastric juice infected with H. pylori might have important role in upper respiratory tract. However it has not been elucidated. Therefore this study aim to clarify whether H. pylori play a role in the etiology and pathogenesis of throat infection. 307 volunteers were participated in this study. Throat swabs from tonsils and oropharynx were collected, conventional bacteriological methods were applied for identification of pathogenic bacteria, followed by PCR confirmation. Along with, serum sample were collected for determination of anti-H. pylori IgG titer by quantitative ELISA method. Prior ICT antibody-based screening test were performed. Simultaneously questionnaire data form from our participants were collected for statistical analysis. This study was designed as case control study. From throat swabs Streptococcus pyogenes was the most common in our isolates. The mean of IgG antibody titer was 95.21 RU/ml, the positive samples for IgG was quite 88.2%. Clinical respiratory symptoms were observed only in 9.7% of participants in this study 89% of them confirmed with H. pylori. Statistical data showed very high significant correlation between pathogenic bacteria S. pyogenes and H. pylori infection.},
 year = {2021}
}

Copy | Download