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Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty

Received: 1 November 2020     Accepted: 19 November 2020     Published: 30 November 2020
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Abstract

Background: Investigate the risk factors of recurrent vertebral compression fractures after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF). Method: Data of 401 patients with osteoporotic vertebral compression fractures treated by PVP from March 2013 to June 2018 were retrospectively analyzed, and were divided into re-fracture group and nonre-fracture group according to the postoperative recurrence of vertebral compression fractures. The following parameters were observed, including age, gender, bone mineral density (BMD), correction degree of kyphosis, recovery degree of vertebral height, amount of bone cement injected, Pfirrmann classification of adjacent intervertebral disc of hurt vertebral, and bone cement leakage in intervertebral disc. Then, the above parameters were statistically analyzed by univariate and multivariate analysis to explore the risk factors of vertebral recurrent fracture after PVP. Result: Among 401 patients, 34 (34 /401, 8.4%) recurred OVCF after PVP. Statistical analysis showed that the risk of recurrent vertebral fracture increased by 3.732 times (95% CI 1.107-12.581) when Pfirrmann classification of adjacent intervertebral disc was in degeneration grade. The risk of recurrent vertebral fracture was significantly increased by 31.818 times (95% CI 13.384-75.640) when bone cement leakage occurred in intervertebral disc. Conclusion: Pfirrmann classification of adjacent intervertebral disc and bone cement leakage in intervertebral disc are significantly correlated with the recurrence of vertebral fracture after PVP. In PVP operation, avoiding the bone cement leakage in intervertebral disc can significantly reduce the recurrence of vertebral compression fractures.

Published in Journal of Surgery (Volume 8, Issue 6)
DOI 10.11648/j.js.20200806.16
Page(s) 204-208
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Percutaneous Vertebroplasty, Osteoporotic Vertebral Compression Fractures, Recurrent Fractures, Risk Factors

References
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Cite This Article
  • APA Style

    Jiang Du, Chenhuan Lu, Jing Wang. (2020). Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty. Journal of Surgery, 8(6), 204-208. https://doi.org/10.11648/j.js.20200806.16

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    ACS Style

    Jiang Du; Chenhuan Lu; Jing Wang. Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty. J. Surg. 2020, 8(6), 204-208. doi: 10.11648/j.js.20200806.16

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    AMA Style

    Jiang Du, Chenhuan Lu, Jing Wang. Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty. J Surg. 2020;8(6):204-208. doi: 10.11648/j.js.20200806.16

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  • @article{10.11648/j.js.20200806.16,
      author = {Jiang Du and Chenhuan Lu and Jing Wang},
      title = {Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty},
      journal = {Journal of Surgery},
      volume = {8},
      number = {6},
      pages = {204-208},
      doi = {10.11648/j.js.20200806.16},
      url = {https://doi.org/10.11648/j.js.20200806.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20200806.16},
      abstract = {Background: Investigate the risk factors of recurrent vertebral compression fractures after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF). Method: Data of 401 patients with osteoporotic vertebral compression fractures treated by PVP from March 2013 to June 2018 were retrospectively analyzed, and were divided into re-fracture group and nonre-fracture group according to the postoperative recurrence of vertebral compression fractures. The following parameters were observed, including age, gender, bone mineral density (BMD), correction degree of kyphosis, recovery degree of vertebral height, amount of bone cement injected, Pfirrmann classification of adjacent intervertebral disc of hurt vertebral, and bone cement leakage in intervertebral disc. Then, the above parameters were statistically analyzed by univariate and multivariate analysis to explore the risk factors of vertebral recurrent fracture after PVP. Result: Among 401 patients, 34 (34 /401, 8.4%) recurred OVCF after PVP. Statistical analysis showed that the risk of recurrent vertebral fracture increased by 3.732 times (95% CI 1.107-12.581) when Pfirrmann classification of adjacent intervertebral disc was in degeneration grade. The risk of recurrent vertebral fracture was significantly increased by 31.818 times (95% CI 13.384-75.640) when bone cement leakage occurred in intervertebral disc. Conclusion: Pfirrmann classification of adjacent intervertebral disc and bone cement leakage in intervertebral disc are significantly correlated with the recurrence of vertebral fracture after PVP. In PVP operation, avoiding the bone cement leakage in intervertebral disc can significantly reduce the recurrence of vertebral compression fractures.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty
    AU  - Jiang Du
    AU  - Chenhuan Lu
    AU  - Jing Wang
    Y1  - 2020/11/30
    PY  - 2020
    N1  - https://doi.org/10.11648/j.js.20200806.16
    DO  - 10.11648/j.js.20200806.16
    T2  - Journal of Surgery
    JF  - Journal of Surgery
    JO  - Journal of Surgery
    SP  - 204
    EP  - 208
    PB  - Science Publishing Group
    SN  - 2330-0930
    UR  - https://doi.org/10.11648/j.js.20200806.16
    AB  - Background: Investigate the risk factors of recurrent vertebral compression fractures after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF). Method: Data of 401 patients with osteoporotic vertebral compression fractures treated by PVP from March 2013 to June 2018 were retrospectively analyzed, and were divided into re-fracture group and nonre-fracture group according to the postoperative recurrence of vertebral compression fractures. The following parameters were observed, including age, gender, bone mineral density (BMD), correction degree of kyphosis, recovery degree of vertebral height, amount of bone cement injected, Pfirrmann classification of adjacent intervertebral disc of hurt vertebral, and bone cement leakage in intervertebral disc. Then, the above parameters were statistically analyzed by univariate and multivariate analysis to explore the risk factors of vertebral recurrent fracture after PVP. Result: Among 401 patients, 34 (34 /401, 8.4%) recurred OVCF after PVP. Statistical analysis showed that the risk of recurrent vertebral fracture increased by 3.732 times (95% CI 1.107-12.581) when Pfirrmann classification of adjacent intervertebral disc was in degeneration grade. The risk of recurrent vertebral fracture was significantly increased by 31.818 times (95% CI 13.384-75.640) when bone cement leakage occurred in intervertebral disc. Conclusion: Pfirrmann classification of adjacent intervertebral disc and bone cement leakage in intervertebral disc are significantly correlated with the recurrence of vertebral fracture after PVP. In PVP operation, avoiding the bone cement leakage in intervertebral disc can significantly reduce the recurrence of vertebral compression fractures.
    VL  - 8
    IS  - 6
    ER  - 

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Author Information
  • Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou, China

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