Moringa oleifera popularly known as Zogale in Northern Nigeria is one of the most widely distributed and cultivated plant species in the region. Moringa oleifera is a small or middle-sized tree, about 10m in height and is cultivated for different purposes such as vegetable, spice, medicine, for cooking and cosmetic oil. Different parts of this plant contain a profile of important minerals, and are a good source of protein, vitamins, β-carotene, amino acids and various phenolics. It was reported that Moringa trees are used to overcome malnutrition, especially in infants and nursing mothers, due to the presence of essential nutritional composition. Moringa leaves contain more vitamin A, calcium, iron, vitamin C, and potassium than carrots, milk, spinach, oranges and bananas respectively, and the protein quality of Moringa leaves is more than that of milk and eggs. An overview of phytochemical constituents present, biological activities, therapeutic potentials and their nutritional values are given in this paper.
Published in | Journal of Drug Design and Medicinal Chemistry (Volume 3, Issue 4) |
DOI | 10.11648/j.jddmc.20170304.12 |
Page(s) | 60-66 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
Moringa oleifera, Zogale, Phytochemical, Nutritional, Glucosinolate, β-Carotene
[1] | H. E., Mshelia, (2016). “Exploring the Nigerian Natural Products from plant through Ethnobotany for National Development”. A paper presented at 15th National Conference of SCSN ABU Zaria 30th August – 3rd Sep. 2016. |
[2] | Pan S-Y, Zhou S-F, Gao S-H et al (2013) New perspectives on how to discover drugs from herbal medicines: CAM’s outstanding contribution to modern therapeutics, new perspectives on how to discover drugs from herbal medicines: CAM’s outstanding contribution to modern therapeutics. Evid Based Complement Altern Med, 2013:e627375. doi:10.1155/2013/627375 |
[3] | Kunyanga C. N., Imungi J. K., Vellingiri V (2013) Nutritional evaluation of indigenous foods with potential food-based solution to alleviate hunger and malnutrition in Kenya. J Appl Biosci, 67:5277–5288. doi:10.4314/jab.v67i0.95049. |
[4] | Padayachee B, Baijnath H (2012) An overview of the medicinal importance of Moringaceae. J Med Plants Res 6:5831–5839. |
[5] | Saini R. K., (2015) Studies on enhancement of carotenoids folic acid iron and their bioavailability in M oleifera and in vitro propagation. University of Mysore, Mysore. |
[6] | Stevens GC, Baiyeri KP, Akinnnagbe O (2013) Ethno-medicinal and culinary uses of M. oleifera Lam. in Nigeria. J Med Plants Res 7:799–804. |
[7] | Saini R. K., Manoj P, Shetty NP et al (2014a) Dietary iron supplements and Moringa oleifera leaves influence the liver hepcidin messenger RNA expression and biochemical indices of iron status in rats. Nutr Res 34:630–638. doi:10.1016/j.nutres.2014. 07.003 |
[8] | Saini R. K., Prashanth KVH, Shetty NP, Giridhar P (2014b) Elicitors, SA and MJ enhance carotenoids and tocopherol biosynthesis and expression of antioxidant related genes in M. oleifera Lam. leaves. Acta Physiol Plant 36:2695–2704. doi:10.1007/s11738014-1640-7 |
[9] | Saini R. K., Shetty NP, Giridhar P (2014c) Carotenoid content in vegetative and reproductive parts of commercially grown Moringa oleifera Lam. cultivars from India by LC–MS. Eur Food Res Technol 238:971–978. |
[10] | Saini R. K., Shetty NP, Giridhar P (2014d) GC-FID/MS analysis of fatty acids in Indian cultivars of M. oleifera: potential sources of PUFA. J Am Oil Chem Soc 91:1029–1034 |
[11] | Azam MM, Waris A, Nahar NM (2005) Prospects and potential of fatty acid methyl esters of some non-traditional seed oils for use as biodiesel in India. Biomass Bioenergy 29:293–302. |
[12] | Rashid U, Anwar F, Moser BR, Knothe G (2008) Moringa oleifera oil: a possible source of biodiesel. Bioresour Technol 99:8175–8179. doi:10.1016/j.biortech.2008.03.066 |
[13] | Mofijur M, Masjuki H. H., Kalam MA et al (2014) Comparative evaluation of performance and emission characteristics of Moringa oleifera and Palm oil based biodiesel in a diesel engine. Ind Crops Prod 53:78–84. doi:10.1016/j.indcrop.2013. 12.011 |
[14] | Kansal SK, Kumari A (2014) Potential of M. oleifera for the treatment of water and wastewater. Chem Rev 114:4993–5010. doi:10.1021/cr400093w |
[15] | Upadhyay P., Yadar, M. K., Mishra, S., Sharma, P., and Purohits (2015). “Moringa oleifera; A review of the medical evidence for its nutritional and pharmacological properties”. Int. J. Res. Pharm. Sci. 5(2), 12-16. |
[16] | Pullen J, Saeed K (2014) Experimental study of the factors affecting the oxidation stability of biodiesel FAME fuels. Fuel Process Technol 125:223–235. doi:10.1016/j.fuproc.2014.03.032 |
[17] | T. H. Ganatra, H. U., Joshi, N. P., Bhalodia, R. T., Desia, and R. P., Tirgar. (2012). “A panoramic view on pharmacognostic, pharmacological, nutritional, therapeutic, and prophylaetic values of M. oleifera Lam”. Int. Res. J. Pharm. 3(6). |
[18] | T. Radovich, 2011 (Revised). Farm and Forestry production and marketing profile for Moringa. In. eleritch, C. R. (ed). Speciality crops for pacific island agroforestry. |
[19] | P. S., Kumar, D. Mishra G. Ghosh, and C. S., Panda (2010). Medicinal uses and pharmacological properties of Moringa oleifera.” Int. J. phytomed. 2:210-216. |
[20] | E. N. Ali (2014). “Moringa oleifera leaves possible uses as environmentally friendly material: A review”. Int. J. chemical, Env. Biol. Sci. 2(2), 141-145. |
[21] | A. Annongu, O. R. Karim, A. A. Toye F. E. Sola-Ojo, R. M. O. Kayode, A. H. A. Badamos, O. I. Alli and K. D. Adeyemi (2014). “Geo-Assessment of chemical composition and nutritional Evaluation of Moringa oleifera seeds in nutrition of Broilers.” J. Agric. Sci. 6(4), 119-124. |
[22] | El-massry, F. H. M., Mossa, M. E. M. and S. M. Youssef. (2013). Moringa Oleifera plant” valve and utilization in food processing”. Egypt J. Agric. Res. 91(4), 1597-1609. |
[23] | Azra, Y. (2011). “Exploring the potential of moringa (Moringa oleifera) Leaf Extract as Natural plant growth enhancer”. A thesis submitted to the department of Agronomy, university of Agriculture, Faisalabad, Pakistan. |
[24] | B. R., Goyal, B. B., Agrawal, R. K., Goyal and A. A., Mehta (2007). “Phyto-pharmacology of moringa oleifera Lam. O. An overview. Nat. product radiance 6(4), 347-353. |
[25] | Monica, A. valdez-Solana et al., (2015). Nutritional content and elemental and phytochemical Analyses of Moringa oleifera grown in Mexico”. J. chem. http://dx.dio.og/10.1155/2015/860381. |
[26] | Kawo, A. H., Abdullahi, B. A., Gaiya, Z. A., Halilu, A., Dabai M. and Dakare, M. A. (2009). “Preliminary phytochemical screening, proximate and elemental composition of Moringa oleifera lam seed power”. Bayero J. pure App. Sci. 2(1): 96-100. |
[27] | S. Muhammad, M. N Danjuma and I. A Abdulkarim. (2005). “Ehtnobotanical survey of medicinal plants in metropolitan Kano, Nigeria”. Int. J. public Health Res. 3(6): 345-351. |
[28] | Nkechi V. Offiah et al., (2011). “Ethno botanical survey of medicinal plants used int eh treatment of animal diarrhea in Plateau State, Nigeria”. BMC vet. Res. 7:36, http://www.biomedcentral.com/1746-6148/7/36. |
[29] | A. Mudansiru, A. M. Haidara, S. Ibrahim, U. Zaharaddeen, and A. M. Darma. (2016). “Ethno botanical survey of some medicinal plants of Gumel town, Jigawa State, Nigeria.” Int. J. Sci. Res. Engr. 3(3): 10-15. |
[30] | Fahey, J. W., Zalcmann, A. T., and Talalay, P. (2001) “the chemical diversity and distribution of glucosinolates and isothiocyanates among plants”. Phytochemsitry, 56(10): 5-51. |
[31] | Pandey A, Pradheep K, Gupta R et al (2011) ‘‘Drumstick tree’’(Moringa oleifera Lam.): a multipurpose potential species in India. Genet Resour Crop Evol 58:453–460. |
[32] | Leone A, Spada A, Battezzati A et al (2015) Cultivation, genetic, ethno pharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: an overview. Int J Mol Sci 16:12791–12835. doi:10.3390/ijms160612791 |
[33] | Zaku SG, Emmanuel S, Tukur AA, Kabir A (2015) Moringa oleifera: an underutilized tree in nigeria with amazing versatility: a review. Afr J Food Sci 9:456–461. |
[34] | Saini R., Saad KR, Ravishankar GA et al (2013) Genetic diversity of commercially grown Moringa oleifera Lam. cultivars from India by RAPD, ISSR and cytochrome P450-based markers. Plant Syst Evol 299:1205–1213. |
[35] | Da Silva JPV, Serra TM, Gossmann M et al (2010) Moringa oleifera oil: studies of characterization and biodiesel production. Biomass Bioenergy 34:1527–1530. doi:10.1016/j.biombioe. 2010.04.002 |
[36] | Ayerza R (2011) Seed yield components, oil content, and fatty acid composition of two cultivars of Moringa (Moringa oleifera Lam.) growing in the Arid Chaco of Argentina. Int Crops Prod 33:389–394. doi:10.1016/j.indcrop.2010.11.003 |
[37] | Patel S, Thakur AS, Chandy A, Manigauha A (2010) Moringa oleifera: a review of there medicinal and economical importance to the health and nation. Drug Invent Today 2:339–342. |
[38] | Saini R. K., Shetty NP, Prakash M, Giridhar P (2014e) Effect of dehydration methods on retention of carotenoids, tocopherols, ascorbic acid and antioxidant activity in Moringa oleifera leaves and preparation of a RTE product. J Food Sci Technol 51:2176–2182. |
[39] | Anwar F, Latif S, Ashraf M, Gilani AH (2007) Moringa oleifera: a food plant with multiple medicinal uses. Phytother Res 21:17–25. doi:10.1002/ptr.2023 |
[40] | Coppin JP, Xu Y, Chen H et al (2013) Determination of flavonoids by LC/MS and anti-inflammatory activity in Moringa oleifera. J Func Foods 5:1892–1899 |
[41] | Nouman W, Anwar F, Gull T et al (2016) Profiling of polyphenolics, nutrients and antioxidant potential of germplasm’s leaves from seven cultivars of Moringa oleifera Lam. Int Crops Prod 83:166–176. doi:10.1016/j.indcrop.2015.12.032 |
[42] | Saini R. K., Manoj P, Shetty NP et al (2016) Relative bioavailability of folate from the traditional food plant Moringa oleifera L. as evaluated in a rat model. J Food Sci Technol 53:511–520. doi:10. 1007/s13197-015-1828-x |
[43] | Scotti M, Stella L, Shearer E. J., Stover P. J. (2013) Modeling cellular compartmentation in one-carbon metabolism. Wiley Interdiscip Rev Syst Biol Med 5:343–365. doi:10.1002/wsbm.1209 |
[44] | Williams J, Mai CT, Mulinare J et al (2015) Updated estimates of neural tube defects prevented by mandatory folic acid fortification—United States, 1995–2011. MMWR Morb Mortal Wkly Rep 64:1–5. |
[45] | Sa´nchez-Machado DI, Lo´pez-Cervantes J, Nu´n˜ez-Gaste´lum JA et al (2015) Effect of the refining process on Moringa oleifera seed oil quality. Food Chem 187:53–57. doi:10.1016/j.foodchem.2015. 04.031 |
[46] | Bhutada PR, Jadhav AJ, Pinjari DV et al (2016) Solvent assisted extraction of oil from Moringa oleifera Lam. seeds. Ind Crops Prod 82:74–80. doi:10.1016/j.indcrop.2015.12.004 |
[47] | Ogunsina BS, Radha C, Govardhan Singh RS (2010) Physicochemical and functional properties of full-fat and defatted Moringa oleifera kernel flour. Int J Food Sci Technol 45:2433–2439. doi:10.1111/j.1365-2621.2010.02423.x |
[48] | Teixeira EMB, Carvalho MRB, Neves VA et al (2014) Chemical characteristics and fractionation of proteins from Moringa oleifera Lam. leaves. Food Chem 147:51–54. doi:10.1016/j. foodchem.2013.09.135 |
[49] | Oyeyinka AT, Oyeyinka SA (2016) Moringa oleifera as a food fortificant: recent trends and prospects. J Saudi Soc Agric Sci. doi:10.1016/j.jssas.2016.02.002 |
[50] | Farooq F, Rai M, Tiwari A et al (2012) Medicinal properties of Moringa oleifera: an overview of promising healer. J Med Plants Res 6:4368–4374. |
[51] | Mbikay M (2012) Therapeutic potential of Moringa oleifera leaves in chronic hyperglycemia and dyslipidemia: a review. Front Pharmacol 3:24. doi:10.3389/fphar.2012.00024 |
[52] | Stohs S. J., Hartman MJ (2015) Review of the Safety and Efficacy of Moringa oleifera. Phytother Res PTR 29:796–804. doi:10.1002/ptr.5325 |
[53] | Sreelatha S, Jeyachitra A, Padma PR (2011) Antiproliferation and induction of apoptosis by Moringa oleifera leaf extract on human cancer cells. Food Chem Toxicol 49:1270–1275. |
[54] | Arun Giridhari V, Malathi D, Geetha K (2011) Anti diabetic property of drumstick (Moringa oleifera) leaf tablets. Int J Health Nutr 2:1–5. |
[55] | Jain PG, Patil SD, Haswani NG et al (2010) Hypolipidemic activity of Moringa oleifera Lam., Moringaceae, on high fat diet induced hyperlipidemia in albino rats. Rev Bras Farmacogn 20:969–973. doi:10.1590/S0102-695X2010005000038 |
[56] | Nambiar VS, Guin P, Parnami S, Daniel M (2010) Impact of antioxidants from drumstick leaves on the lipid profile of hyperlipidemics. J Herb Med Toxicol 4:165–172. |
[57] | Berkovich L, Earon G, Ron I et al (2013) Moringa oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells. BMC Complement Altern Med 13:212. |
[58] | W. Jed, Fahey, Sc. D. (2005). “Moringa Oleifera: A review of the medical evidence for its nutritional, therapeutic and prophylactic properties. Part 1”. Trees for life J. 1:5 http://www.TFLjournal.org/article.php/2005/201124931586. |
APA Style
Adamu Idris Maizuwo, Aminu Sharif Hassan, Hassanah Momoh, Jabir Abdullahi Muhammad. (2017). Phytochemical Constituents, Biological Activities, Therapeutic Potentials and Nutritional Values of Moringa oleifera (Zogale): A Review. Journal of Drug Design and Medicinal Chemistry, 3(4), 60-66. https://doi.org/10.11648/j.jddmc.20170304.12
ACS Style
Adamu Idris Maizuwo; Aminu Sharif Hassan; Hassanah Momoh; Jabir Abdullahi Muhammad. Phytochemical Constituents, Biological Activities, Therapeutic Potentials and Nutritional Values of Moringa oleifera (Zogale): A Review. J. Drug Des. Med. Chem. 2017, 3(4), 60-66. doi: 10.11648/j.jddmc.20170304.12
AMA Style
Adamu Idris Maizuwo, Aminu Sharif Hassan, Hassanah Momoh, Jabir Abdullahi Muhammad. Phytochemical Constituents, Biological Activities, Therapeutic Potentials and Nutritional Values of Moringa oleifera (Zogale): A Review. J Drug Des Med Chem. 2017;3(4):60-66. doi: 10.11648/j.jddmc.20170304.12
@article{10.11648/j.jddmc.20170304.12, author = {Adamu Idris Maizuwo and Aminu Sharif Hassan and Hassanah Momoh and Jabir Abdullahi Muhammad}, title = {Phytochemical Constituents, Biological Activities, Therapeutic Potentials and Nutritional Values of Moringa oleifera (Zogale): A Review}, journal = {Journal of Drug Design and Medicinal Chemistry}, volume = {3}, number = {4}, pages = {60-66}, doi = {10.11648/j.jddmc.20170304.12}, url = {https://doi.org/10.11648/j.jddmc.20170304.12}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jddmc.20170304.12}, abstract = {Moringa oleifera popularly known as Zogale in Northern Nigeria is one of the most widely distributed and cultivated plant species in the region. Moringa oleifera is a small or middle-sized tree, about 10m in height and is cultivated for different purposes such as vegetable, spice, medicine, for cooking and cosmetic oil. Different parts of this plant contain a profile of important minerals, and are a good source of protein, vitamins, β-carotene, amino acids and various phenolics. It was reported that Moringa trees are used to overcome malnutrition, especially in infants and nursing mothers, due to the presence of essential nutritional composition. Moringa leaves contain more vitamin A, calcium, iron, vitamin C, and potassium than carrots, milk, spinach, oranges and bananas respectively, and the protein quality of Moringa leaves is more than that of milk and eggs. An overview of phytochemical constituents present, biological activities, therapeutic potentials and their nutritional values are given in this paper.}, year = {2017} }
TY - JOUR T1 - Phytochemical Constituents, Biological Activities, Therapeutic Potentials and Nutritional Values of Moringa oleifera (Zogale): A Review AU - Adamu Idris Maizuwo AU - Aminu Sharif Hassan AU - Hassanah Momoh AU - Jabir Abdullahi Muhammad Y1 - 2017/10/28 PY - 2017 N1 - https://doi.org/10.11648/j.jddmc.20170304.12 DO - 10.11648/j.jddmc.20170304.12 T2 - Journal of Drug Design and Medicinal Chemistry JF - Journal of Drug Design and Medicinal Chemistry JO - Journal of Drug Design and Medicinal Chemistry SP - 60 EP - 66 PB - Science Publishing Group SN - 2472-3576 UR - https://doi.org/10.11648/j.jddmc.20170304.12 AB - Moringa oleifera popularly known as Zogale in Northern Nigeria is one of the most widely distributed and cultivated plant species in the region. Moringa oleifera is a small or middle-sized tree, about 10m in height and is cultivated for different purposes such as vegetable, spice, medicine, for cooking and cosmetic oil. Different parts of this plant contain a profile of important minerals, and are a good source of protein, vitamins, β-carotene, amino acids and various phenolics. It was reported that Moringa trees are used to overcome malnutrition, especially in infants and nursing mothers, due to the presence of essential nutritional composition. Moringa leaves contain more vitamin A, calcium, iron, vitamin C, and potassium than carrots, milk, spinach, oranges and bananas respectively, and the protein quality of Moringa leaves is more than that of milk and eggs. An overview of phytochemical constituents present, biological activities, therapeutic potentials and their nutritional values are given in this paper. VL - 3 IS - 4 ER -