Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives

Saranya Sathiyavasan; Maheswaran Sithambaresan; Parthiban Gunasingham; Ratnasothy Srikaran

doi:doi:10.11648/j.ijsts.20170505.16

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Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives

Saranya Sathiyavasan, Maheswaran Sithambaresan, Parthiban Gunasingham, Ratnasothy Srikaran

Published in International Journal of Science, Technology and Society (Volume 5, Issue 5)

Received: 17 August 2017 Accepted: 25 August 2017 Published: 19 September 2017

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Abstract

N-Oxidobenzamide derivatives are powerful metal ion chelators. It is used as inhibitors of hypertension, tumor growth, inﬂammation, infectious agents, asthma, arthritis, Alzheimer’s diseases and more. In this study, Copper (ll) (SRC1 and SRC3) and Cadmium (ll) (SRC2 and SRC4) complexes were synthesized from potassium N-Oxidobenzamide derivative ligands and they were characterized by using various techniques such as Infra-Red spectra, electronic spectra, melting point and conductivity measurements. The electronic spectral study and the melting point analysis revealed that the ligands are coordinated to the metal centre. IR and conductivity analyses confirm the coordination of hydroxamate ions to the metal centre as O, O-bidentate mode via the hydroxyl oxygen and the carbonyl oxygen atoms of the ligands. The proposed molecular structures for the newly formed complexes are also given.

Published in	International Journal of Science, Technology and Society (Volume 5, Issue 5)
DOI	10.11648/j.ijsts.20170505.16
Page(s)	179-181
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Hydroxamic Acids, N-Oxidobenzamide, Copper(ll) Complex, Cadmium (ll) Complex and Analytical Techniques

References

[1]	Rittakakkar, Theoretical studies on Hydroxamic Acids, Springer –Verlag Berlin Heideberg, (2013), P: 19-53.
[2]	Naqeebullah, Yang Farina, KokMeng Chan, Lo Kong Mun Nor Fadilah Rajab and Theng Choon Ooi, Diorganotin (IV) Derivatives of N-Methyl p-Fluorobenzo-Hydroxamic Acid: Preparation, Spectral Characterization, X-ray Diffraction Studies and Antitumor Activity, Molecules (2013), 18, P: 8696-8711.
[3]	Farkas, E., Csoka, H., Gama, S., Santos, M. A. Dihydroxamate based siderophore model, piperazine-1,4-bis-(N-methyl-acetohydroxamic acid (PIPDMAHA), as a chelating agent of molybdenum(VI). Talanta (2002), 57, 935–943.
[4]	Munster, P. N.; Troso-Sandoval, T.; Rosen, N.; Rifkind, R.; Marks, P. A.; Richon, V. M. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces differentiation of human breast cancer cells. Cancer Res. (2001), 61, 8492–8497.
[5]	Codd. R, Traversing the coordination chemistry and chemical biology of hydroxamic acid, Coord. Chem, Rev.(2008), 252, P: 1387–1408.
[6]	S. Sasi, M. Sithambaresan, MRP Kurup, HK Fun, Syntheses, EPR spectral studies and crystal structures of manganese (II) complexes of neutral N, N donor bidentate Schiff bases and azide/thiocyanate as coligand, Polyhedron (2010), 29, p: 2643-2650.
[7]	Pavia, Lampman, Kriz, Vyvyan, Intoduction to Spectroscopy, Fourth Edition, Brooks/Cole Cengage Learning, (2007), P: 15-89, 381-413.
[8]	Jain, R.; Sundram, A.; Lopez, S.; Neckermann, G.; Wu, C.; Hackbarth, C.; Chen, D.; Wang, W.; Ryder, NS.; Weidmann, B.; et al. α-Substituted hydroxamic acids as novel bacterial deformylase inhibitor-based antibacterial agents. Bioorg. Med. Chem. Lett. (2003), 13, 4223–4228.
[9]	Petrosyan, V. S.; Yashina, N. S.; Ponomarev, S. V. Syntheses, Structures and biological activites of Organogermaniun and Organotin derivatives of hydroxamic acids. Met. Based Drugs (1998), 5, 237–244.
[10]	Baul, T.; Masharing, C.; Ruisi, G.; Jirasko, R.; Holcapek, M.; De Vos, D.; Wolstenholme, D.; Linden, A. Self-assembly of extended Schiff base amino acetate keletons, 2-{[(2Z)-(3-hydroxy-1-Methyl-2-butenylidene)]amino}Phenylpropio-nate and 2-{[(E)-1-(2-hydroxy-aryl) alkylidene] amino} Phenyl-propionate skeletons incorporating organotin(IV) moieties: Synthesis, spectroscopic characterization, crystal structures, and in vitro cytotoxic activity. J. Organomet. Chem. (2007), 692, 4849–4862.

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Saranya Sathiyavasan, Maheswaran Sithambaresan, Parthiban Gunasingham, Ratnasothy Srikaran. (2017). Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives. International Journal of Science, Technology and Society, 5(5), 179-181. https://doi.org/10.11648/j.ijsts.20170505.16

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Saranya Sathiyavasan; Maheswaran Sithambaresan; Parthiban Gunasingham; Ratnasothy Srikaran. Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives. Int. J. Sci. Technol. Soc. 2017, 5(5), 179-181. doi: 10.11648/j.ijsts.20170505.16

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AMA Style

Saranya Sathiyavasan, Maheswaran Sithambaresan, Parthiban Gunasingham, Ratnasothy Srikaran. Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives. Int J Sci Technol Soc. 2017;5(5):179-181. doi: 10.11648/j.ijsts.20170505.16

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@article{10.11648/j.ijsts.20170505.16,
  author = {Saranya Sathiyavasan and Maheswaran Sithambaresan and Parthiban Gunasingham and Ratnasothy Srikaran},
  title = {Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives},
  journal = {International Journal of Science, Technology and Society},
  volume = {5},
  number = {5},
  pages = {179-181},
  doi = {10.11648/j.ijsts.20170505.16},
  url = {https://doi.org/10.11648/j.ijsts.20170505.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijsts.20170505.16},
  abstract = {N-Oxidobenzamide derivatives are powerful metal ion chelators. It is used as inhibitors of hypertension, tumor growth, inﬂammation, infectious agents, asthma, arthritis, Alzheimer’s diseases and more. In this study, Copper (ll) (SRC1 and SRC3) and Cadmium (ll) (SRC2 and SRC4) complexes were synthesized from potassium N-Oxidobenzamide derivative ligands and they were characterized by using various techniques such as Infra-Red spectra, electronic spectra, melting point and conductivity measurements. The electronic spectral study and the melting point analysis revealed that the ligands are coordinated to the metal centre. IR and conductivity analyses confirm the coordination of hydroxamate ions to the metal centre as O, O-bidentate mode via the hydroxyl oxygen and the carbonyl oxygen atoms of the ligands. The proposed molecular structures for the newly formed complexes are also given.},
 year = {2017}
}

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TY  - JOUR
T1  - Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives
AU  - Saranya Sathiyavasan
AU  - Maheswaran Sithambaresan
AU  - Parthiban Gunasingham
AU  - Ratnasothy Srikaran
Y1  - 2017/09/19
PY  - 2017
N1  - https://doi.org/10.11648/j.ijsts.20170505.16
DO  - 10.11648/j.ijsts.20170505.16
T2  - International Journal of Science, Technology and Society
JF  - International Journal of Science, Technology and Society
JO  - International Journal of Science, Technology and Society
SP  - 179
EP  - 181
PB  - Science Publishing Group
SN  - 2330-7420
UR  - https://doi.org/10.11648/j.ijsts.20170505.16
AB  - N-Oxidobenzamide derivatives are powerful metal ion chelators. It is used as inhibitors of hypertension, tumor growth, inﬂammation, infectious agents, asthma, arthritis, Alzheimer’s diseases and more. In this study, Copper (ll) (SRC1 and SRC3) and Cadmium (ll) (SRC2 and SRC4) complexes were synthesized from potassium N-Oxidobenzamide derivative ligands and they were characterized by using various techniques such as Infra-Red spectra, electronic spectra, melting point and conductivity measurements. The electronic spectral study and the melting point analysis revealed that the ligands are coordinated to the metal centre. IR and conductivity analyses confirm the coordination of hydroxamate ions to the metal centre as O, O-bidentate mode via the hydroxyl oxygen and the carbonyl oxygen atoms of the ligands. The proposed molecular structures for the newly formed complexes are also given.
VL  - 5
IS  - 5
ER  -

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Author Information

Saranya Sathiyavasan

Department of Human Biology, Faculty of Health-Care Sciences, Eastern University of Sri Lanka, Batticaloa, Sri Lanka
Maheswaran Sithambaresan

Department of Chemistry, Faculty of Science, Eastern University of Sri Lanka, Batticaloa, Sri Lanka
Parthiban Gunasingham

Department of Chemistry, Faculty of Science, Eastern University of Sri Lanka, Batticaloa, Sri Lanka
Ratnasothy Srikaran

Department of Chemistry, Faculty of Science, University of Jaffna, Jaffna, Sri Lanka

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APA Style

Saranya Sathiyavasan, Maheswaran Sithambaresan, Parthiban Gunasingham, Ratnasothy Srikaran. (2017). Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives. International Journal of Science, Technology and Society, 5(5), 179-181. https://doi.org/10.11648/j.ijsts.20170505.16

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ACS Style

Saranya Sathiyavasan; Maheswaran Sithambaresan; Parthiban Gunasingham; Ratnasothy Srikaran. Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives. Int. J. Sci. Technol. Soc. 2017, 5(5), 179-181. doi: 10.11648/j.ijsts.20170505.16

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AMA Style

Saranya Sathiyavasan, Maheswaran Sithambaresan, Parthiban Gunasingham, Ratnasothy Srikaran. Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives. Int J Sci Technol Soc. 2017;5(5):179-181. doi: 10.11648/j.ijsts.20170505.16

Copy | Download

@article{10.11648/j.ijsts.20170505.16,
  author = {Saranya Sathiyavasan and Maheswaran Sithambaresan and Parthiban Gunasingham and Ratnasothy Srikaran},
  title = {Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives},
  journal = {International Journal of Science, Technology and Society},
  volume = {5},
  number = {5},
  pages = {179-181},
  doi = {10.11648/j.ijsts.20170505.16},
  url = {https://doi.org/10.11648/j.ijsts.20170505.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijsts.20170505.16},
  abstract = {N-Oxidobenzamide derivatives are powerful metal ion chelators. It is used as inhibitors of hypertension, tumor growth, inﬂammation, infectious agents, asthma, arthritis, Alzheimer’s diseases and more. In this study, Copper (ll) (SRC1 and SRC3) and Cadmium (ll) (SRC2 and SRC4) complexes were synthesized from potassium N-Oxidobenzamide derivative ligands and they were characterized by using various techniques such as Infra-Red spectra, electronic spectra, melting point and conductivity measurements. The electronic spectral study and the melting point analysis revealed that the ligands are coordinated to the metal centre. IR and conductivity analyses confirm the coordination of hydroxamate ions to the metal centre as O, O-bidentate mode via the hydroxyl oxygen and the carbonyl oxygen atoms of the ligands. The proposed molecular structures for the newly formed complexes are also given.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives
AU  - Saranya Sathiyavasan
AU  - Maheswaran Sithambaresan
AU  - Parthiban Gunasingham
AU  - Ratnasothy Srikaran
Y1  - 2017/09/19
PY  - 2017
N1  - https://doi.org/10.11648/j.ijsts.20170505.16
DO  - 10.11648/j.ijsts.20170505.16
T2  - International Journal of Science, Technology and Society
JF  - International Journal of Science, Technology and Society
JO  - International Journal of Science, Technology and Society
SP  - 179
EP  - 181
PB  - Science Publishing Group
SN  - 2330-7420
UR  - https://doi.org/10.11648/j.ijsts.20170505.16
AB  - N-Oxidobenzamide derivatives are powerful metal ion chelators. It is used as inhibitors of hypertension, tumor growth, inﬂammation, infectious agents, asthma, arthritis, Alzheimer’s diseases and more. In this study, Copper (ll) (SRC1 and SRC3) and Cadmium (ll) (SRC2 and SRC4) complexes were synthesized from potassium N-Oxidobenzamide derivative ligands and they were characterized by using various techniques such as Infra-Red spectra, electronic spectra, melting point and conductivity measurements. The electronic spectral study and the melting point analysis revealed that the ligands are coordinated to the metal centre. IR and conductivity analyses confirm the coordination of hydroxamate ions to the metal centre as O, O-bidentate mode via the hydroxyl oxygen and the carbonyl oxygen atoms of the ligands. The proposed molecular structures for the newly formed complexes are also given.
VL  - 5
IS  - 5
ER  -

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