Congenital and genetic ocular disorders are linked to parental consanguinity. The aims was to investigate the effects of consanguineous marriages on the refractive errors of preschool-aged and adolescent patients. Two sample groups were recruited: the preschooler group (3–6 years; 335 participants) and the adolescent group (12–20 years; 998 participants). The required sample size was calculated using a sample size estimation software. Visual acuity was measured using the 15-line Lea symbols chart in the pre-school aged group and non-illuminated ETDRS VA chart in the adolescent group. Spherical equivalent refractive errors were noted with near-retinoscopy technique in young children and with the ARK-30 autorefractor in the adolescent group. In order to explore the impact of consanguineous marriages, the data were analyzed separately based on the age group using SPSS version 21 software. In the preschooler group, myopia was found in 4.2%, hyperopia in 8.1%, and astigmatism in 20%. Three children had high myopic scores (-10.00 D, -13.50 D and -17.50 D). In the adolescent group, 45.6% participants were myopic, 3.8% were hyperopic, and 22.3% were astigmatic. Despite the higher frequency of RE in those 15 years and older in the cousins group and the consanguineous parents of the three preschool-aged children with high myopia, there were no statistically significant (p>0.05) evidence that consanguineous marriages impact the refractive errors of their children. In conclusion, despite previous studies showing a link between ocular genetic or congenital disorders and consanguinity, no such link could be established with regard to refractive errors.
| Published in | International Journal of Ophthalmology & Visual Science (Volume 4, Issue 4) |
| DOI | 10.11648/j.ijovs.20190404.15 |
| Page(s) | 81-87 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Consanguinity, Consanguineous Marriages, Refractive Errors, Myopia, Saudi, Arabs
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APA Style
Ali Mazyed Alsaqr. (2019). Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A Cross-sectional Study. International Journal of Ophthalmology & Visual Science, 4(4), 81-87. https://doi.org/10.11648/j.ijovs.20190404.15
ACS Style
Ali Mazyed Alsaqr. Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A Cross-sectional Study. Int. J. Ophthalmol. Vis. Sci. 2019, 4(4), 81-87. doi: 10.11648/j.ijovs.20190404.15
AMA Style
Ali Mazyed Alsaqr. Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A Cross-sectional Study. Int J Ophthalmol Vis Sci. 2019;4(4):81-87. doi: 10.11648/j.ijovs.20190404.15
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Download@article{10.11648/j.ijovs.20190404.15,
author = {Ali Mazyed Alsaqr},
title = {Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A Cross-sectional Study},
journal = {International Journal of Ophthalmology & Visual Science},
volume = {4},
number = {4},
pages = {81-87},
doi = {10.11648/j.ijovs.20190404.15},
url = {https://doi.org/10.11648/j.ijovs.20190404.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20190404.15},
abstract = {Congenital and genetic ocular disorders are linked to parental consanguinity. The aims was to investigate the effects of consanguineous marriages on the refractive errors of preschool-aged and adolescent patients. Two sample groups were recruited: the preschooler group (3–6 years; 335 participants) and the adolescent group (12–20 years; 998 participants). The required sample size was calculated using a sample size estimation software. Visual acuity was measured using the 15-line Lea symbols chart in the pre-school aged group and non-illuminated ETDRS VA chart in the adolescent group. Spherical equivalent refractive errors were noted with near-retinoscopy technique in young children and with the ARK-30 autorefractor in the adolescent group. In order to explore the impact of consanguineous marriages, the data were analyzed separately based on the age group using SPSS version 21 software. In the preschooler group, myopia was found in 4.2%, hyperopia in 8.1%, and astigmatism in 20%. Three children had high myopic scores (-10.00 D, -13.50 D and -17.50 D). In the adolescent group, 45.6% participants were myopic, 3.8% were hyperopic, and 22.3% were astigmatic. Despite the higher frequency of RE in those 15 years and older in the cousins group and the consanguineous parents of the three preschool-aged children with high myopia, there were no statistically significant (p>0.05) evidence that consanguineous marriages impact the refractive errors of their children. In conclusion, despite previous studies showing a link between ocular genetic or congenital disorders and consanguinity, no such link could be established with regard to refractive errors.},
year = {2019}
}
TY - JOUR T1 - Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A Cross-sectional Study AU - Ali Mazyed Alsaqr Y1 - 2019/11/05 PY - 2019 N1 - https://doi.org/10.11648/j.ijovs.20190404.15 DO - 10.11648/j.ijovs.20190404.15 T2 - International Journal of Ophthalmology & Visual Science JF - International Journal of Ophthalmology & Visual Science JO - International Journal of Ophthalmology & Visual Science SP - 81 EP - 87 PB - Science Publishing Group SN - 2637-3858 UR - https://doi.org/10.11648/j.ijovs.20190404.15 AB - Congenital and genetic ocular disorders are linked to parental consanguinity. The aims was to investigate the effects of consanguineous marriages on the refractive errors of preschool-aged and adolescent patients. Two sample groups were recruited: the preschooler group (3–6 years; 335 participants) and the adolescent group (12–20 years; 998 participants). The required sample size was calculated using a sample size estimation software. Visual acuity was measured using the 15-line Lea symbols chart in the pre-school aged group and non-illuminated ETDRS VA chart in the adolescent group. Spherical equivalent refractive errors were noted with near-retinoscopy technique in young children and with the ARK-30 autorefractor in the adolescent group. In order to explore the impact of consanguineous marriages, the data were analyzed separately based on the age group using SPSS version 21 software. In the preschooler group, myopia was found in 4.2%, hyperopia in 8.1%, and astigmatism in 20%. Three children had high myopic scores (-10.00 D, -13.50 D and -17.50 D). In the adolescent group, 45.6% participants were myopic, 3.8% were hyperopic, and 22.3% were astigmatic. Despite the higher frequency of RE in those 15 years and older in the cousins group and the consanguineous parents of the three preschool-aged children with high myopia, there were no statistically significant (p>0.05) evidence that consanguineous marriages impact the refractive errors of their children. In conclusion, despite previous studies showing a link between ocular genetic or congenital disorders and consanguinity, no such link could be established with regard to refractive errors. VL - 4 IS - 4 ER -
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