A common diseased condition includes eye infections like conductivities and corneal disorder such as glaucoma etc. Some of the typical classes of drugs used for the ocular delivery are miotics, mydriatics/cycloplegics, anti-inflammatory, anti-infective, surgical adjuvant and diagnostics. This review presents an outline of the prospective of chitosan-based nanomedicine for the treatment of ocular infection for improving the corneal residence time and in vitro bioavailability. In addition, its minimum toxicity and good ocular tolerance, chitosan exhibits constructive biological behavior, like bioadhesion and good permeability with optimum physiochemical characteristics, which make it a unique biocompatible material for the ophthalmic application. The review summarizes the application of chitosan based nanomedicine such as nanoparticles, solid lipid nanoparticles, nanosuspention, nanosponge and nanogels for the treatment of ocular diseases. The results reported provide evidence of the potential of chitosan being natural polymers for enhancing therapeutics effect of drugs.
| Published in | International Journal of Ophthalmology & Visual Science (Volume 2, Issue 4) |
| DOI | 10.11648/j.ijovs.20170204.14 |
| Page(s) | 98-105 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
Chitosan Nanoparticles, Nanomedicine, Corneal Residence Time, in Vitro Bioavailability
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APA Style
Varsha Gharge, Pravin Pawar. (2017). Recent Trends in Chitosan Based Nanotechnology: A Reference to Ocular Drug Delivery System. International Journal of Ophthalmology & Visual Science, 2(4), 98-105. https://doi.org/10.11648/j.ijovs.20170204.14
ACS Style
Varsha Gharge; Pravin Pawar. Recent Trends in Chitosan Based Nanotechnology: A Reference to Ocular Drug Delivery System. Int. J. Ophthalmol. Vis. Sci. 2017, 2(4), 98-105. doi: 10.11648/j.ijovs.20170204.14
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Download@article{10.11648/j.ijovs.20170204.14,
author = {Varsha Gharge and Pravin Pawar},
title = {Recent Trends in Chitosan Based Nanotechnology: A Reference to Ocular Drug Delivery System},
journal = {International Journal of Ophthalmology & Visual Science},
volume = {2},
number = {4},
pages = {98-105},
doi = {10.11648/j.ijovs.20170204.14},
url = {https://doi.org/10.11648/j.ijovs.20170204.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20170204.14},
abstract = {A common diseased condition includes eye infections like conductivities and corneal disorder such as glaucoma etc. Some of the typical classes of drugs used for the ocular delivery are miotics, mydriatics/cycloplegics, anti-inflammatory, anti-infective, surgical adjuvant and diagnostics. This review presents an outline of the prospective of chitosan-based nanomedicine for the treatment of ocular infection for improving the corneal residence time and in vitro bioavailability. In addition, its minimum toxicity and good ocular tolerance, chitosan exhibits constructive biological behavior, like bioadhesion and good permeability with optimum physiochemical characteristics, which make it a unique biocompatible material for the ophthalmic application. The review summarizes the application of chitosan based nanomedicine such as nanoparticles, solid lipid nanoparticles, nanosuspention, nanosponge and nanogels for the treatment of ocular diseases. The results reported provide evidence of the potential of chitosan being natural polymers for enhancing therapeutics effect of drugs.},
year = {2017}
}
TY - JOUR T1 - Recent Trends in Chitosan Based Nanotechnology: A Reference to Ocular Drug Delivery System AU - Varsha Gharge AU - Pravin Pawar Y1 - 2017/09/21 PY - 2017 N1 - https://doi.org/10.11648/j.ijovs.20170204.14 DO - 10.11648/j.ijovs.20170204.14 T2 - International Journal of Ophthalmology & Visual Science JF - International Journal of Ophthalmology & Visual Science JO - International Journal of Ophthalmology & Visual Science SP - 98 EP - 105 PB - Science Publishing Group SN - 2637-3858 UR - https://doi.org/10.11648/j.ijovs.20170204.14 AB - A common diseased condition includes eye infections like conductivities and corneal disorder such as glaucoma etc. Some of the typical classes of drugs used for the ocular delivery are miotics, mydriatics/cycloplegics, anti-inflammatory, anti-infective, surgical adjuvant and diagnostics. This review presents an outline of the prospective of chitosan-based nanomedicine for the treatment of ocular infection for improving the corneal residence time and in vitro bioavailability. In addition, its minimum toxicity and good ocular tolerance, chitosan exhibits constructive biological behavior, like bioadhesion and good permeability with optimum physiochemical characteristics, which make it a unique biocompatible material for the ophthalmic application. The review summarizes the application of chitosan based nanomedicine such as nanoparticles, solid lipid nanoparticles, nanosuspention, nanosponge and nanogels for the treatment of ocular diseases. The results reported provide evidence of the potential of chitosan being natural polymers for enhancing therapeutics effect of drugs. VL - 2 IS - 4 ER -
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