Introduction. Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. As of 2018, the World Health Organization (WHO) reports that approximately 10 million people worldwide have it. Tuberculosis is one of the top 10 causes of death. Spinal tuberculosis represents 50 to 60% of osteoarticular tuberculosis. Three main radioclinic forms have been described: tuberculous spondylodiscitis or Pott's disease, tuberculous spondylitis and primary tuberculosis of the posterior arch. The early diagnosis of spinal tuberculosis has become easy thanks to the progress of imaging and the development of disco-vertebral biopsy techniques. Chronic hemodialysis patients are particularly at risk of tuberculosis. Spondylodiscitis is more frequent in this population and threatens the vital prognosis. Observation: We report two cases of tuberculous spondylodiscitis diagnosed in the context of pelvic and lumbar pain. The biological work-up noted an inflammatory hypochromic microcytic anemia. The infectious workup was negative. MRI and CT scans showed lumbar spondylodiscitis in both cases. No disco-vertebral biopsy was performed. The diagnosis of tuberculous spondylodiscitis was made on the basis of clinical and imaging findings. A quadrithérapie anti bacillaire was instituted. The short-term evolution was favorable with disappearance of the pain, but one patient died of an unclear cause because the death occurred at home. Conclusion: Spinal tuberculosis is far from being rare in hemodialysis patients in Mali. It should always be considered in the presence of unlabelled pain, which will lead to the request of imaging examinations in order to evoke the diagnosis and to initiate antituberculosis treatment.
Published in | International Journal of Medical Case Reports (Volume 1, Issue 1) |
DOI | 10.11648/j.ijmcr.20220101.11 |
Page(s) | 1-5 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Spondylodiscitis, Tuberculosis, Hemodialysis, Anti-bacillary Treatment
[1] | Wafae Bekhechi, Hakim Chiali, Leila Borsali, Rawda Sari-Hamidou, Mustapha Benmansour. Renal tuberculosis disease indicative of Pott’s disease. Néphrologie & Thérapeutique 17 (2021) 185-189. |
[2] | OMS. Tuberculose liée au VIH: le nombre de cas et de décès atteint de proportions alarmantes en Afrique. Rapport sur la lutte antituberculeuse. OMS, Genève, 24 Mars 2005. |
[3] | M. F. Ladeb, H. Riahi, M. Chelli Bouaziz, M. Mechri. Clinical evolution of tuberculous spondylodiscitis in Tunisia. Bull Acad Natl Med (2019) 203, 328-333. |
[4] | Solovic. M; Sester. M; Gomez-Reino. JJ; Rieder. HL; Ehlers. S; Milburn. HJ et al. The risk of tuberculosis related to tumor necrosis factor antagonist Thérapies: TBNET consensus statement. Eur Resp 2010; 36 (5): 1185-1206. |
[5] | Toloba. Y; Diallo. S; Maiga. Y; Sissoko. BF; Ouattara. K; Soumaré. D; Sidibé. S. Tuberculose vertébrale (Mal de pott): aspect épidémio-clinique, radiologique et évolutif au CHU du Point G; Mali Médical 2011. Tome XXVI N°2. |
[6] | Américan Thoracic Society; centers for Disease control and prévention; infections Diseases society: controlling tuberculosis in the United stades. Am J Respir Crit Care Med 2005; 172: 1169-2127. |
[7] | Man. NK; Touam. M; Jungers. P. Hemodialysis for renal replacement thérapy Lavoisier SAS 2020; 56: 112-6. |
[8] | Fongoro. S; Diallo. D; Toloba. Y; Dialla. S; Maiga. H; Arama. C et al: the case of tuberculosis to the chronic hémodialysis patients at the teaching hospital of point G in Bamako about 10 remarks. Mali Med 2011; 2: 27-30. |
[9] | Boubou. M; Houssaini Squalli. H; Maaroufi. M; Tizniti. S. Apports de l’IRM dans les spondylodiscites tuberculeuses. Revue Maghrébine de Neurosciences RMNSC 2012; 5. |
[10] | Ellner. JJ. Review: the immune response in humantuberculosis-implications for tuberculosis control: J Infect Dis 1997; 176: 1351. |
[11] | Chon. KJ; Fang. HC; Bai. KJ; Hwang. SJ; Yang. WC; Chung. HM. Tuberculosis in maintenance dialysis patients. Nephron 2001; 88: 138-143. |
[12] | Neaver. P; Lifeso. RM. The radiological diagnosis of tuberculosis of the adulte spine. Skeletal Radiol 1984; 12: 178. |
[13] | H assani. M. Paraplégie brutale sur spondylodiscite tuberculeuse chez un patient hémodialysé. IOSR Journal of dental and Médical sciences (IOSR- JDMS) 2018; 17: 66-70. |
[14] | Boussel. L; Marchand. B; Blineau. N; Pariset. C; Hermier. M; Picand. G. Imagerie de la tuberculose ostéo-articulaire. J. radiol 2002; 83 (9): 1025-1034. |
[15] | Held. M; Laubscher; Mears. S et al. Diagnostic accuracy of the Xpert MTB/RIF Assay for extrapulmonary tuberculopsis in children with musculoskeletal infections. Pediatr Infect Dis J 2016; 35: 11. |
APA Style
Saharé Fongoro, Magara Samaké, Seydou Sy, Hamadoun Yattara, Moctar Coulibaly, et al. (2022). Tuberculous Spondylodiscitis (Pott's Disease) in Hemodialysis Patients: A Case Report from the Point G University Hospital, Bamako, Mali. International Journal of Medical Case Reports, 1(1), 1-5. https://doi.org/10.11648/j.ijmcr.20220101.11
ACS Style
Saharé Fongoro; Magara Samaké; Seydou Sy; Hamadoun Yattara; Moctar Coulibaly, et al. Tuberculous Spondylodiscitis (Pott's Disease) in Hemodialysis Patients: A Case Report from the Point G University Hospital, Bamako, Mali. Int. J. Med. Case Rep. 2022, 1(1), 1-5. doi: 10.11648/j.ijmcr.20220101.11
AMA Style
Saharé Fongoro, Magara Samaké, Seydou Sy, Hamadoun Yattara, Moctar Coulibaly, et al. Tuberculous Spondylodiscitis (Pott's Disease) in Hemodialysis Patients: A Case Report from the Point G University Hospital, Bamako, Mali. Int J Med Case Rep. 2022;1(1):1-5. doi: 10.11648/j.ijmcr.20220101.11
@article{10.11648/j.ijmcr.20220101.11, author = {Saharé Fongoro and Magara Samaké and Seydou Sy and Hamadoun Yattara and Moctar Coulibaly and Aboubacar Sidiki Fofana and Djénèba Diallo and Atabième Kodio and Djénéba Maiga and Sah Dit Baba Coulibaly and Nanko Doumbia and Aboudou Messoum Dolo and Moustapha Tangara and Nouhoum Coulibaly and Kalilou Coulibaly and Ibrahima Koné}, title = {Tuberculous Spondylodiscitis (Pott's Disease) in Hemodialysis Patients: A Case Report from the Point G University Hospital, Bamako, Mali}, journal = {International Journal of Medical Case Reports}, volume = {1}, number = {1}, pages = {1-5}, doi = {10.11648/j.ijmcr.20220101.11}, url = {https://doi.org/10.11648/j.ijmcr.20220101.11}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmcr.20220101.11}, abstract = {Introduction. Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. As of 2018, the World Health Organization (WHO) reports that approximately 10 million people worldwide have it. Tuberculosis is one of the top 10 causes of death. Spinal tuberculosis represents 50 to 60% of osteoarticular tuberculosis. Three main radioclinic forms have been described: tuberculous spondylodiscitis or Pott's disease, tuberculous spondylitis and primary tuberculosis of the posterior arch. The early diagnosis of spinal tuberculosis has become easy thanks to the progress of imaging and the development of disco-vertebral biopsy techniques. Chronic hemodialysis patients are particularly at risk of tuberculosis. Spondylodiscitis is more frequent in this population and threatens the vital prognosis. Observation: We report two cases of tuberculous spondylodiscitis diagnosed in the context of pelvic and lumbar pain. The biological work-up noted an inflammatory hypochromic microcytic anemia. The infectious workup was negative. MRI and CT scans showed lumbar spondylodiscitis in both cases. No disco-vertebral biopsy was performed. The diagnosis of tuberculous spondylodiscitis was made on the basis of clinical and imaging findings. A quadrithérapie anti bacillaire was instituted. The short-term evolution was favorable with disappearance of the pain, but one patient died of an unclear cause because the death occurred at home. Conclusion: Spinal tuberculosis is far from being rare in hemodialysis patients in Mali. It should always be considered in the presence of unlabelled pain, which will lead to the request of imaging examinations in order to evoke the diagnosis and to initiate antituberculosis treatment.}, year = {2022} }
TY - JOUR T1 - Tuberculous Spondylodiscitis (Pott's Disease) in Hemodialysis Patients: A Case Report from the Point G University Hospital, Bamako, Mali AU - Saharé Fongoro AU - Magara Samaké AU - Seydou Sy AU - Hamadoun Yattara AU - Moctar Coulibaly AU - Aboubacar Sidiki Fofana AU - Djénèba Diallo AU - Atabième Kodio AU - Djénéba Maiga AU - Sah Dit Baba Coulibaly AU - Nanko Doumbia AU - Aboudou Messoum Dolo AU - Moustapha Tangara AU - Nouhoum Coulibaly AU - Kalilou Coulibaly AU - Ibrahima Koné Y1 - 2022/04/22 PY - 2022 N1 - https://doi.org/10.11648/j.ijmcr.20220101.11 DO - 10.11648/j.ijmcr.20220101.11 T2 - International Journal of Medical Case Reports JF - International Journal of Medical Case Reports JO - International Journal of Medical Case Reports SP - 1 EP - 5 PB - Science Publishing Group SN - 2994-7049 UR - https://doi.org/10.11648/j.ijmcr.20220101.11 AB - Introduction. Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. As of 2018, the World Health Organization (WHO) reports that approximately 10 million people worldwide have it. Tuberculosis is one of the top 10 causes of death. Spinal tuberculosis represents 50 to 60% of osteoarticular tuberculosis. Three main radioclinic forms have been described: tuberculous spondylodiscitis or Pott's disease, tuberculous spondylitis and primary tuberculosis of the posterior arch. The early diagnosis of spinal tuberculosis has become easy thanks to the progress of imaging and the development of disco-vertebral biopsy techniques. Chronic hemodialysis patients are particularly at risk of tuberculosis. Spondylodiscitis is more frequent in this population and threatens the vital prognosis. Observation: We report two cases of tuberculous spondylodiscitis diagnosed in the context of pelvic and lumbar pain. The biological work-up noted an inflammatory hypochromic microcytic anemia. The infectious workup was negative. MRI and CT scans showed lumbar spondylodiscitis in both cases. No disco-vertebral biopsy was performed. The diagnosis of tuberculous spondylodiscitis was made on the basis of clinical and imaging findings. A quadrithérapie anti bacillaire was instituted. The short-term evolution was favorable with disappearance of the pain, but one patient died of an unclear cause because the death occurred at home. Conclusion: Spinal tuberculosis is far from being rare in hemodialysis patients in Mali. It should always be considered in the presence of unlabelled pain, which will lead to the request of imaging examinations in order to evoke the diagnosis and to initiate antituberculosis treatment. VL - 1 IS - 1 ER -