Knowledge of spatial and temporal distribution of genetic diversity within and between populations is a crucial step for establishing strategies management of Animal genetic resources. This study aims to contribute to a better understanding of the genetic structure of local sheep breeds. Specifically, it will characterize the genetic diversity, differentiation and evolution of the SRY gene in four main lineages of Ladoum sheep in Senegal. After alignments and corrections, a total of 42 sequences were used for analysis of SRY genetic diversity and demographic evolution. The standard indices of genetic diversity, genetic differenciation, analyses of hierarchical molecular variance (AMOVA) and demographic tests were compute. Analysis of genetic variability parameters in the overall population revealed a low level of polymorphism in the SRY gene. Haplotypic diversity is much higher than the average nucleotide divergence between all pairs of haplotypes. The genetic distances, as well as the values of the genetic differentiation factor beetween lineages, reveal two genetic groups; one made up of the individuals of “Birahim” and the other, grouping the three lineages individuals. Differences in frequencies of essential proteins for a multitude of functions in the body are observed between the "Birahim" lineage and the others. The comparative trends in genetic diversity indices, the shape of the mismatch distribution curves, demographic indices and demogenetic tests show a rapid and recent expansion population from an ancestral small size. The Z-test analysis of selection revealed that SRY gene is under selection. Unlike “Batling” who is under negative selection, "Birahim" and "Gorgui" are under positive selection. This study has made a significant contribution to understanding the genetic structure of the Ladoum raised in Senegal.
| Published in | International Journal of Genetics and Genomics (Volume 11, Issue 1) |
| DOI | 10.11648/j.ijgg.20231101.12 |
| Page(s) | 6-17 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Genetic, Diversity, Evolution, SRY, Polymorphism, Scheep, Ladoum
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APA Style
Sembene Pape Madiop, Mbaye Fatimata, Sembene Pape Mbacke. (2023). Genetic Diversity and Demographic Evolution Using SRY Gene Polymorphism in Four Lineages of Ladoum Sheep in Senegal. International Journal of Genetics and Genomics, 11(1), 6-17. https://doi.org/10.11648/j.ijgg.20231101.12
ACS Style
Sembene Pape Madiop; Mbaye Fatimata; Sembene Pape Mbacke. Genetic Diversity and Demographic Evolution Using SRY Gene Polymorphism in Four Lineages of Ladoum Sheep in Senegal. Int. J. Genet. Genomics 2023, 11(1), 6-17. doi: 10.11648/j.ijgg.20231101.12
AMA Style
Sembene Pape Madiop, Mbaye Fatimata, Sembene Pape Mbacke. Genetic Diversity and Demographic Evolution Using SRY Gene Polymorphism in Four Lineages of Ladoum Sheep in Senegal. Int J Genet Genomics. 2023;11(1):6-17. doi: 10.11648/j.ijgg.20231101.12
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Download@article{10.11648/j.ijgg.20231101.12,
author = {Sembene Pape Madiop and Mbaye Fatimata and Sembene Pape Mbacke},
title = {Genetic Diversity and Demographic Evolution Using SRY Gene Polymorphism in Four Lineages of Ladoum Sheep in Senegal},
journal = {International Journal of Genetics and Genomics},
volume = {11},
number = {1},
pages = {6-17},
doi = {10.11648/j.ijgg.20231101.12},
url = {https://doi.org/10.11648/j.ijgg.20231101.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijgg.20231101.12},
abstract = {Knowledge of spatial and temporal distribution of genetic diversity within and between populations is a crucial step for establishing strategies management of Animal genetic resources. This study aims to contribute to a better understanding of the genetic structure of local sheep breeds. Specifically, it will characterize the genetic diversity, differentiation and evolution of the SRY gene in four main lineages of Ladoum sheep in Senegal. After alignments and corrections, a total of 42 sequences were used for analysis of SRY genetic diversity and demographic evolution. The standard indices of genetic diversity, genetic differenciation, analyses of hierarchical molecular variance (AMOVA) and demographic tests were compute. Analysis of genetic variability parameters in the overall population revealed a low level of polymorphism in the SRY gene. Haplotypic diversity is much higher than the average nucleotide divergence between all pairs of haplotypes. The genetic distances, as well as the values of the genetic differentiation factor beetween lineages, reveal two genetic groups; one made up of the individuals of “Birahim” and the other, grouping the three lineages individuals. Differences in frequencies of essential proteins for a multitude of functions in the body are observed between the "Birahim" lineage and the others. The comparative trends in genetic diversity indices, the shape of the mismatch distribution curves, demographic indices and demogenetic tests show a rapid and recent expansion population from an ancestral small size. The Z-test analysis of selection revealed that SRY gene is under selection. Unlike “Batling” who is under negative selection, "Birahim" and "Gorgui" are under positive selection. This study has made a significant contribution to understanding the genetic structure of the Ladoum raised in Senegal.},
year = {2023}
}
TY - JOUR T1 - Genetic Diversity and Demographic Evolution Using SRY Gene Polymorphism in Four Lineages of Ladoum Sheep in Senegal AU - Sembene Pape Madiop AU - Mbaye Fatimata AU - Sembene Pape Mbacke Y1 - 2023/02/28 PY - 2023 N1 - https://doi.org/10.11648/j.ijgg.20231101.12 DO - 10.11648/j.ijgg.20231101.12 T2 - International Journal of Genetics and Genomics JF - International Journal of Genetics and Genomics JO - International Journal of Genetics and Genomics SP - 6 EP - 17 PB - Science Publishing Group SN - 2376-7359 UR - https://doi.org/10.11648/j.ijgg.20231101.12 AB - Knowledge of spatial and temporal distribution of genetic diversity within and between populations is a crucial step for establishing strategies management of Animal genetic resources. This study aims to contribute to a better understanding of the genetic structure of local sheep breeds. Specifically, it will characterize the genetic diversity, differentiation and evolution of the SRY gene in four main lineages of Ladoum sheep in Senegal. After alignments and corrections, a total of 42 sequences were used for analysis of SRY genetic diversity and demographic evolution. The standard indices of genetic diversity, genetic differenciation, analyses of hierarchical molecular variance (AMOVA) and demographic tests were compute. Analysis of genetic variability parameters in the overall population revealed a low level of polymorphism in the SRY gene. Haplotypic diversity is much higher than the average nucleotide divergence between all pairs of haplotypes. The genetic distances, as well as the values of the genetic differentiation factor beetween lineages, reveal two genetic groups; one made up of the individuals of “Birahim” and the other, grouping the three lineages individuals. Differences in frequencies of essential proteins for a multitude of functions in the body are observed between the "Birahim" lineage and the others. The comparative trends in genetic diversity indices, the shape of the mismatch distribution curves, demographic indices and demogenetic tests show a rapid and recent expansion population from an ancestral small size. The Z-test analysis of selection revealed that SRY gene is under selection. Unlike “Batling” who is under negative selection, "Birahim" and "Gorgui" are under positive selection. This study has made a significant contribution to understanding the genetic structure of the Ladoum raised in Senegal. VL - 11 IS - 1 ER -
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