Contrast-enhanced ultrasound (CEUS) is an imaging modality that utilizes a non-nephrotoxic, intravascular microbubble agent to capture real-time perfusion of the target organ. CEUS has demonstrated utility for the evaluation and surveillance of indeterminate renal lesions in patients who are unable to receive conventional contrast agents, yet its potential utility in renal surgery remains poorly defined in the current literature. We present a series of 4 patients who underwent successful intraoperative CEUS during partial nephrectomy (PN) to help define renal mass contour and proximity to vascular structures in an attempt to optimize renal function after PN. All cases were endophytic with moderate-high complexity (R.E.N.A.L. scores>9). CEUS was safely performed in all cases providing excellent tumor contour definition. In one case, CEUS provided better visualization of tumor proximity within the hilum than conventional US, facilitating surgical resection and reconstruction. In another case, CEUS provided better definition of tumor contour, allowing wedge resection rather than heminephrectomy. Margins were negative in all cases. The average global renal function preserved following PN was 90%. While grey-scale US with color Doppler is usually sufficient for intraoperative tumor visualization, CEUS can be considered during PN for complex endophytic, infiltrative or hilar tumors where accurate delineation of tumor contour is critical.
| Published in | International Journal of Clinical Urology (Volume 5, Issue 2) |
| DOI | 10.11648/j.ijcu.20210502.21 |
| Page(s) | 113-117 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
Contrast-enhanced Ultrasound, Kidney Neoplasms, Nephron-sparing Surgery, Functional Outcomes
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APA Style
Brendan Thomas Frainey, Peace Ugonma Orji, Christopher Coppa, Steven Charles Campbell. (2021). Contrast-Enhanced Ultrasound for Intraoperative Tumor Contour Definition During Complex Partial Nephrectomy. International Journal of Clinical Urology, 5(2), 113-117. https://doi.org/10.11648/j.ijcu.20210502.21
ACS Style
Brendan Thomas Frainey; Peace Ugonma Orji; Christopher Coppa; Steven Charles Campbell. Contrast-Enhanced Ultrasound for Intraoperative Tumor Contour Definition During Complex Partial Nephrectomy. Int. J. Clin. Urol. 2021, 5(2), 113-117. doi: 10.11648/j.ijcu.20210502.21
AMA Style
Brendan Thomas Frainey, Peace Ugonma Orji, Christopher Coppa, Steven Charles Campbell. Contrast-Enhanced Ultrasound for Intraoperative Tumor Contour Definition During Complex Partial Nephrectomy. Int J Clin Urol. 2021;5(2):113-117. doi: 10.11648/j.ijcu.20210502.21
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Download@article{10.11648/j.ijcu.20210502.21,
author = {Brendan Thomas Frainey and Peace Ugonma Orji and Christopher Coppa and Steven Charles Campbell},
title = {Contrast-Enhanced Ultrasound for Intraoperative Tumor Contour Definition During Complex Partial Nephrectomy},
journal = {International Journal of Clinical Urology},
volume = {5},
number = {2},
pages = {113-117},
doi = {10.11648/j.ijcu.20210502.21},
url = {https://doi.org/10.11648/j.ijcu.20210502.21},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20210502.21},
abstract = {Contrast-enhanced ultrasound (CEUS) is an imaging modality that utilizes a non-nephrotoxic, intravascular microbubble agent to capture real-time perfusion of the target organ. CEUS has demonstrated utility for the evaluation and surveillance of indeterminate renal lesions in patients who are unable to receive conventional contrast agents, yet its potential utility in renal surgery remains poorly defined in the current literature. We present a series of 4 patients who underwent successful intraoperative CEUS during partial nephrectomy (PN) to help define renal mass contour and proximity to vascular structures in an attempt to optimize renal function after PN. All cases were endophytic with moderate-high complexity (R.E.N.A.L. scores>9). CEUS was safely performed in all cases providing excellent tumor contour definition. In one case, CEUS provided better visualization of tumor proximity within the hilum than conventional US, facilitating surgical resection and reconstruction. In another case, CEUS provided better definition of tumor contour, allowing wedge resection rather than heminephrectomy. Margins were negative in all cases. The average global renal function preserved following PN was 90%. While grey-scale US with color Doppler is usually sufficient for intraoperative tumor visualization, CEUS can be considered during PN for complex endophytic, infiltrative or hilar tumors where accurate delineation of tumor contour is critical.},
year = {2021}
}
TY - JOUR T1 - Contrast-Enhanced Ultrasound for Intraoperative Tumor Contour Definition During Complex Partial Nephrectomy AU - Brendan Thomas Frainey AU - Peace Ugonma Orji AU - Christopher Coppa AU - Steven Charles Campbell Y1 - 2021/12/24 PY - 2021 N1 - https://doi.org/10.11648/j.ijcu.20210502.21 DO - 10.11648/j.ijcu.20210502.21 T2 - International Journal of Clinical Urology JF - International Journal of Clinical Urology JO - International Journal of Clinical Urology SP - 113 EP - 117 PB - Science Publishing Group SN - 2640-1355 UR - https://doi.org/10.11648/j.ijcu.20210502.21 AB - Contrast-enhanced ultrasound (CEUS) is an imaging modality that utilizes a non-nephrotoxic, intravascular microbubble agent to capture real-time perfusion of the target organ. CEUS has demonstrated utility for the evaluation and surveillance of indeterminate renal lesions in patients who are unable to receive conventional contrast agents, yet its potential utility in renal surgery remains poorly defined in the current literature. We present a series of 4 patients who underwent successful intraoperative CEUS during partial nephrectomy (PN) to help define renal mass contour and proximity to vascular structures in an attempt to optimize renal function after PN. All cases were endophytic with moderate-high complexity (R.E.N.A.L. scores>9). CEUS was safely performed in all cases providing excellent tumor contour definition. In one case, CEUS provided better visualization of tumor proximity within the hilum than conventional US, facilitating surgical resection and reconstruction. In another case, CEUS provided better definition of tumor contour, allowing wedge resection rather than heminephrectomy. Margins were negative in all cases. The average global renal function preserved following PN was 90%. While grey-scale US with color Doppler is usually sufficient for intraoperative tumor visualization, CEUS can be considered during PN for complex endophytic, infiltrative or hilar tumors where accurate delineation of tumor contour is critical. VL - 5 IS - 2 ER -
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