The Experience and Outcome of Renal Transplantation in Yemen

Nagib Wazea Abuasba; Ibrahim Al Nono; Tawfiq Al Badani; Abd Al Ilah Ghailan; Abdo Zekri

doi:doi:10.11648/j.ijcu.20190302.15

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The Experience and Outcome of Renal Transplantation in Yemen

Nagib Wazea Abuasba, Ibrahim Al Nono, Tawfiq Al Badani, Abd Al Ilah Ghailan, Abdo Zekri

Published in International Journal of Clinical Urology (Volume 3, Issue 2)

Received: 9 November 2019 Accepted: 28 November 2019 Published: 10 December 2019

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Abstract

Access to renal transplantation in the developing world remains limited It remains the treatment of choice for end-stage kidney disease. This procedure not only improves quality of life, but also markedly increases patients’ survival rates. Therefore, this study aimed to evaluate clinical outcomes of renal transplants in our center and to compare the outcomes between the patients who received induction therapy and those patients without such induction. It was a retrospective study conducted at Al Thawra General Hospital, Sana’a on 154 patients. Data were collected on all patients who underwent a renal transplant from 2004 to t 2015. Analyses were performed to assess baseline characteristics, graft and patient survival, as well as the outcomes of patients who given induction therapy. A total of 154 renal transplants were carried out at Al Thawra center. The mean age of patients was 32.42 ± 10.4 years (rang 14 – 66) and the male sex was predominant accounting for 72.7%. There were 93.5% of patients on dialysis and the dialysis time was ≥ 3 years in 72%. The major causes of end-stage kidney disease (ESKD) were chronic pyelonephritis (77.9%), hypertension (13%), glomerulonephritis (3.9%) and diabetes mellitus (2.4%). During the first year following renal transplants, 6 patients (3.9%) complicated by acute rejection episodes that did not reach statistical significance (P > 0.05). It is found that the mortality rate during the 1^st, 5^th, and 10^th years was 1.9%, 9% and 14.9%respectively and the infectious conditions were the most frequent cause of death (13%) followed by cardiovascular events (3.9%) and others (2.5%). Although, the process of renal transplants in Yemen started slowly with the initial support and cooperation of the Egyptians’ transplant surgeons, the overall outcomes are satisfactory and comparable to the universal reports.

Published in	International Journal of Clinical Urology (Volume 3, Issue 2)
DOI	10.11648/j.ijcu.20190302.15
Page(s)	50-55
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Renal Transplantation, Graft Survival Rate, Yemen, Immunosuppressive

References

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[6]	Davidson B, Du Toit T, Jones ESW, Barday Z, Manning K, Mc Curdie F, et al. (2019)Outcomes and challenges of a kidney transplant programme at Groote Schuur Hospital, Cape Town: A South African perspective. PLoS ONE 14 (1): e0211189: https://doi.org/10.1371/journal.pone.0211189.
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Nagib Wazea Abuasba, Ibrahim Al Nono, Tawfiq Al Badani, Abd Al Ilah Ghailan, Abdo Zekri. (2019). The Experience and Outcome of Renal Transplantation in Yemen. International Journal of Clinical Urology, 3(2), 50-55. https://doi.org/10.11648/j.ijcu.20190302.15

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ACS Style

Nagib Wazea Abuasba; Ibrahim Al Nono; Tawfiq Al Badani; Abd Al Ilah Ghailan; Abdo Zekri. The Experience and Outcome of Renal Transplantation in Yemen. Int. J. Clin. Urol. 2019, 3(2), 50-55. doi: 10.11648/j.ijcu.20190302.15

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AMA Style

Nagib Wazea Abuasba, Ibrahim Al Nono, Tawfiq Al Badani, Abd Al Ilah Ghailan, Abdo Zekri. The Experience and Outcome of Renal Transplantation in Yemen. Int J Clin Urol. 2019;3(2):50-55. doi: 10.11648/j.ijcu.20190302.15

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@article{10.11648/j.ijcu.20190302.15,
  author = {Nagib Wazea Abuasba and Ibrahim Al Nono and Tawfiq Al Badani and Abd Al Ilah Ghailan and Abdo Zekri},
  title = {The Experience and Outcome of Renal Transplantation in Yemen},
  journal = {International Journal of Clinical Urology},
  volume = {3},
  number = {2},
  pages = {50-55},
  doi = {10.11648/j.ijcu.20190302.15},
  url = {https://doi.org/10.11648/j.ijcu.20190302.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20190302.15},
  abstract = {Access to renal transplantation in the developing world remains limited It remains the treatment of choice for end-stage kidney disease. This procedure not only improves quality of life, but also markedly increases patients’ survival rates. Therefore, this study aimed to evaluate clinical outcomes of renal transplants in our center and to compare the outcomes between the patients who received induction therapy and those patients without such induction. It was a retrospective study conducted at Al Thawra General Hospital, Sana’a on 154 patients. Data were collected on all patients who underwent a renal transplant from 2004 to t 2015. Analyses were performed to assess baseline characteristics, graft and patient survival, as well as the outcomes of patients who given induction therapy. A total of 154 renal transplants were carried out at Al Thawra center. The mean age of patients was 32.42 ± 10.4 years (rang 14 – 66) and the male sex was predominant accounting for 72.7%. There were 93.5% of patients on dialysis and the dialysis time was ≥ 3 years in 72%. The major causes of end-stage kidney disease (ESKD) were chronic pyelonephritis (77.9%), hypertension (13%), glomerulonephritis (3.9%) and diabetes mellitus (2.4%). During the first year following renal transplants, 6 patients (3.9%) complicated by acute rejection episodes that did not reach statistical significance (P > 0.05). It is found that  the mortality rate during the 1st, 5th, and 10th years was 1.9%, 9% and 14.9%respectively and the infectious conditions were the most frequent cause of death (13%) followed by cardiovascular events (3.9%) and others (2.5%). Although, the process of renal transplants in Yemen started slowly with the initial support and cooperation of the Egyptians’ transplant surgeons, the overall outcomes are satisfactory and comparable to the universal reports.},
 year = {2019}
}

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TY - JOUR
T1 - The Experience and Outcome of Renal Transplantation in Yemen
AU - Nagib Wazea Abuasba
AU - Ibrahim Al Nono
AU - Tawfiq Al Badani
AU - Abd Al Ilah Ghailan
AU - Abdo Zekri
Y1 - 2019/12/10
PY - 2019
N1 - https://doi.org/10.11648/j.ijcu.20190302.15
DO - 10.11648/j.ijcu.20190302.15
T2 - International Journal of Clinical Urology
JF - International Journal of Clinical Urology
JO - International Journal of Clinical Urology
SP - 50
EP - 55
PB - Science Publishing Group
SN - 2640-1355
UR - https://doi.org/10.11648/j.ijcu.20190302.15
AB - Access to renal transplantation in the developing world remains limited It remains the treatment of choice for end-stage kidney disease. This procedure not only improves quality of life, but also markedly increases patients’ survival rates. Therefore, this study aimed to evaluate clinical outcomes of renal transplants in our center and to compare the outcomes between the patients who received induction therapy and those patients without such induction. It was a retrospective study conducted at Al Thawra General Hospital, Sana’a on 154 patients. Data were collected on all patients who underwent a renal transplant from 2004 to t 2015. Analyses were performed to assess baseline characteristics, graft and patient survival, as well as the outcomes of patients who given induction therapy. A total of 154 renal transplants were carried out at Al Thawra center. The mean age of patients was 32.42 ± 10.4 years (rang 14 – 66) and the male sex was predominant accounting for 72.7%. There were 93.5% of patients on dialysis and the dialysis time was ≥ 3 years in 72%. The major causes of end-stage kidney disease (ESKD) were chronic pyelonephritis (77.9%), hypertension (13%), glomerulonephritis (3.9%) and diabetes mellitus (2.4%). During the first year following renal transplants, 6 patients (3.9%) complicated by acute rejection episodes that did not reach statistical significance (P > 0.05). It is found that the mortality rate during the 1st, 5th, and 10th years was 1.9%, 9% and 14.9%respectively and the infectious conditions were the most frequent cause of death (13%) followed by cardiovascular events (3.9%) and others (2.5%). Although, the process of renal transplants in Yemen started slowly with the initial support and cooperation of the Egyptians’ transplant surgeons, the overall outcomes are satisfactory and comparable to the universal reports.
VL - 3
IS - 2
ER -

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Author Information

Nagib Wazea Abuasba

Nephrology Department, Faculty of Medicine, Sana’a University, Sana’a, Yemen
Ibrahim Al Nono

Nephrology Department, Faculty of Medicine, Sana’a University, Sana’a, Yemen
Tawfiq Al Badani

Nephrology Department, Faculty of Medicine, Sana’a University, Sana’a, Yemen
Abd Al Ilah Ghailan

Nephrology Department, Faculty of Medicine, Sana’a University, Sana’a, Yemen
Abdo Zekri

Nephrology Department, Faculty of Medicine, Sana’a University, Sana’a, Yemen

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Nagib Wazea Abuasba, Ibrahim Al Nono, Tawfiq Al Badani, Abd Al Ilah Ghailan, Abdo Zekri. (2019). The Experience and Outcome of Renal Transplantation in Yemen. International Journal of Clinical Urology, 3(2), 50-55. https://doi.org/10.11648/j.ijcu.20190302.15

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ACS Style

Nagib Wazea Abuasba; Ibrahim Al Nono; Tawfiq Al Badani; Abd Al Ilah Ghailan; Abdo Zekri. The Experience and Outcome of Renal Transplantation in Yemen. Int. J. Clin. Urol. 2019, 3(2), 50-55. doi: 10.11648/j.ijcu.20190302.15

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AMA Style

Nagib Wazea Abuasba, Ibrahim Al Nono, Tawfiq Al Badani, Abd Al Ilah Ghailan, Abdo Zekri. The Experience and Outcome of Renal Transplantation in Yemen. Int J Clin Urol. 2019;3(2):50-55. doi: 10.11648/j.ijcu.20190302.15

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@article{10.11648/j.ijcu.20190302.15,
  author = {Nagib Wazea Abuasba and Ibrahim Al Nono and Tawfiq Al Badani and Abd Al Ilah Ghailan and Abdo Zekri},
  title = {The Experience and Outcome of Renal Transplantation in Yemen},
  journal = {International Journal of Clinical Urology},
  volume = {3},
  number = {2},
  pages = {50-55},
  doi = {10.11648/j.ijcu.20190302.15},
  url = {https://doi.org/10.11648/j.ijcu.20190302.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20190302.15},
  abstract = {Access to renal transplantation in the developing world remains limited It remains the treatment of choice for end-stage kidney disease. This procedure not only improves quality of life, but also markedly increases patients’ survival rates. Therefore, this study aimed to evaluate clinical outcomes of renal transplants in our center and to compare the outcomes between the patients who received induction therapy and those patients without such induction. It was a retrospective study conducted at Al Thawra General Hospital, Sana’a on 154 patients. Data were collected on all patients who underwent a renal transplant from 2004 to t 2015. Analyses were performed to assess baseline characteristics, graft and patient survival, as well as the outcomes of patients who given induction therapy. A total of 154 renal transplants were carried out at Al Thawra center. The mean age of patients was 32.42 ± 10.4 years (rang 14 – 66) and the male sex was predominant accounting for 72.7%. There were 93.5% of patients on dialysis and the dialysis time was ≥ 3 years in 72%. The major causes of end-stage kidney disease (ESKD) were chronic pyelonephritis (77.9%), hypertension (13%), glomerulonephritis (3.9%) and diabetes mellitus (2.4%). During the first year following renal transplants, 6 patients (3.9%) complicated by acute rejection episodes that did not reach statistical significance (P > 0.05). It is found that  the mortality rate during the 1st, 5th, and 10th years was 1.9%, 9% and 14.9%respectively and the infectious conditions were the most frequent cause of death (13%) followed by cardiovascular events (3.9%) and others (2.5%). Although, the process of renal transplants in Yemen started slowly with the initial support and cooperation of the Egyptians’ transplant surgeons, the overall outcomes are satisfactory and comparable to the universal reports.},
 year = {2019}
}

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