Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar

Ahmed Mohamed El Zayat; Eman Abdelhalem El Sharrawy; Amr Ali El Swify; Abdel Bade Abd Allah Abdel Maabod

doi:doi:10.11648/j.ijcoms.20180401.14

| Peer-Reviewed

Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar

Ahmed Mohamed El Zayat, Eman Abdelhalem El Sharrawy, Amr Ali El Swify, Abdel Bade Abd Allah Abdel Maabod

Published in International Journal of Clinical Oral and Maxillofacial Surgery (Volume 4, Issue 1)

Received: 17 April 2018 Accepted: 2 May 2018 Published: 2 June 2018

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

The aim of this comparative clinical study was to investigate the effects of preoperative injections of Dexamethasone Sodium Phosphate versus Diclofenac Sodium. The study includes 60 patients (age range 16-35) who were randomly distributed into three equal groups. Edema and trismus was measured preoperatively, immediate, 24 h, 2 week, 1 month postoperatively. Pain was assessed by visual analogue scale. Noteworthy reduction in postoperatively complication associated with Dexamethasone group was noticed. Edema & trismus in control group was greater followed by Diclofenac groups then group I. Pain was greater score in control group followed by Diclofenac group then group I.

Published in	International Journal of Clinical Oral and Maxillofacial Surgery (Volume 4, Issue 1)
DOI	10.11648/j.ijcoms.20180401.14
Page(s)	19-24
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Preoperative Injection, Submucosal, Corticosteriod, Diclofenac Sodium, Mandibular Impacted Third Molar

References

[1]	Marciani RD. Complications of third molar surgery and their management. Atlas Oral Maxillofac Surg Clin North Am. 2012 (2):233-51. [PubMed] [Cross Ref]
[2]	Osunde OD, Adebola RA, Omeje UK. Management of inflammatory complications in third molar surgery: A review of the literature. Afr Health Sci. 2011;11(3):530-537.
[3]	Lopez-Carriches C, Martinez-Gonzalez JM, Donado-Rodriguez M. The use of methylprednisolone versus diclofenac in the treatment of inflammation and trismus after surgical removal of lower third molars. Med Oral Patol Oral Cir Bucal. 2006; 11(5):E440-E445.
[4]	Beirne. Corticosteroids decrease pain, swelling and trismus. Evidence Based Dent. 2013; 14(4):111.
[5]	Shah SA, Khan I, Shah HS. Effectiveness of Submucosal Dexamethasone to Control Postoperative Pain & Swelling in Apicectomy of Maxillary Anterior Teeth. Int J Health Sci (Qassim). 2011; 5(2):156-165.
[6]	Babatunde Olamide Bamgbose, Jelili Adisa Akinwande,Wasiu Lanre Adeyemo. Effects of co-administered dexamethasone and diclofenac potassium on pain, swelling and trismus following third molar surgery. BioMed- center 2005.
[7]	Saito K1, Kaneko A, Machii K, et al. Effectiveness of additional 200mg of celecoxib on postoperative pain after surgical extraction of third molar. 2012feb; 34(2):314-28. doi: 10.1016/j.clinthera.2012.01.004. Epub 2012 Jan 28.
[8]	De Menezes SA,Cury PR. Efficacy of nimesulide versus meloxicam in the control of pain, swelling and trismus following extraction of impacted lower third molar. Int J Oral Maxillofac Surg. 2010 Jun; 39(6):580-4. doi: 10.1016/j.ijom.
[9]	Boworn Klongnoi, Pariya Kaewpradub, Kiatanant Boonsiriseth, et al. Effect of single dose preoperative intramuscular dexamethasone injection on lower impacted third molar surgery. Int. J. Oral Maxillofac. Surg. 2012;41: 376–379. 2011 International Association of Oral and Maxillofacial Surgeons.
[10]	Brown JD, Daniels SE, Bandy DP, et al. Evaluation of multiday analgesia with etoricoxib in a double-blind, randomized controlled trial using the postoperative third-molar extraction dental pain model. J Pain. 2013 Jun; 29(6):492-8. doi: 10.1097/AJP.0b013e318260c144.
[11]	Trindade PA, Giglio FP, Colombini-Ishikiriama BL, et al. 2012 Sublingual ketorolac and sublingual piroxicam are equally effective for postoperative pain,trismus,and swelling management in lower third molar removal.
[12]	Aznar-Arasa L1, Harutunian K, Figueiredo R, et al. Comparative study of preoperative vs postoperative administration of ibuprofen. International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved. 2012.
[13]	Schlieve T, Kolokythas A, Miloro M. Third Molar Surgery Management of complications in oral and maxillofacial surgery. Chicago: Wiley-Blackwell; 2012:25-33.
[14]	Ness G. Impacted teeth. In: Miloro M, Ghali GE, Larsen PE, Waite PD, eds. Peterson’s Principles of Oral and Maxillofacial Surgery. 3rd ed. Connecticut: PMPH-USA; 2012:113-114.
[15]	Jadson Alípio Santana de Sousa Santos, Luiz Carlos Ferreira da Silva, Thiago de Santana Santos, et al. Comparative study of tramadol combined with dexamethasone and Diclofenac sodium in third-molar surgery. Journal of Cranio-Maxillo-Facial Surgery.2012.
[16]	Fragiskos FD. Surgical Extraction of Impacted Teeth. In: Schroder Gabriele M, ed. Oral Surgery. Heidelberg: Springer-Verlag; 2007:195-197.
[17]	Tiigimae-Saar J, Leibur E, Tamme T. Stomatologija. Comparative study of effect of sublingual administration of piroxicam versus ketorolac on postoperative complication 2010; 12(1):17-22.
[18]	Al-Saffar MT. Efficacy of Paracetamol versus Celebrex on the Control of Post Operative Complica-tions of Lower Third Molars. Al–Rafidain Dent J. 2011; 11(1):24-31.
[19]	Häggström, Mikael; Richfield, David. "Diagram of the pathways of human steroidogenesis". WikiJournal of medicine. 1 (1). doi:10.15347/wjm/ 2014.0 05. ISSN 2002-4436.
[20]	Frye CA "Steroids, reproductive endocrine function, and affect. A review". Minerva Ginecol 61 (6): 541–562. PMID 19942840. (2009).
[21]	Pelt AC Glucocorticoids: effects, action mechanisms, and therapeutic uses. Hauppauge, N. Y.: Nova Science. ISBN 978-1617287589. (2011).
[22]	Revollo JR, Cidlowski JA "Mechanisms generating diversity in glucocorticoid receptor signaling". Ann. N. Y. Acad. Sci. 1179: 167–78. doi:10.1111/j.1749-6632.2009.04986.x.PMID 19906239. (October 2009).
[23]	Liapi and Chrousos Chapter 14. Glucocorticoid Therapy and Adrenal Suppression.
[24]	Pazirandeh A, Xue Y, Prestegaard T, et al. "Effects of altered glucocorticoid sensitivity in the T cell lineage on thymocyte and T cell homeostasis". FASEBJ. 2002.
[25]	Herrera-Briones FJ, Prados Sánchez E, Reyes Botella C, et al. Update on the use of corticosteroids in third molar surgery: systematic review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013; 116(5):e342-e351.
[26]	Giovanni Battista Grossi, Carlo Maiorana, Rocco Alberto Garramone, et al. American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 65:2218-2226, 2007.
[27]	Omer Waleed Majid, Waseem Khalid. Effect of submucosal and intramuscular dexamethasone on postoperative sequelae after third molar surgery. 29 October 2010
[28]	Nandini, Gandhiraj. Effect of intramuscular and submucosal examethasone on postoperative sequelae after third molar surgical extraction: Comparative study. doi: 10.1016/j.ajoms.2013.09.010. G.D. 2013.
[29]	Nair RB, Rahman NM, Ummar M, et al. Effect of submucosal injection of dexamethasone on postoperative discomfort after third molar surgery. J Contemp Dent Pract. 2013;14(3):401-404.
[30]	Dhanavelu P, Shanmugapriyan, Ebenezer V, et al. Dexamethasone for third molar surgery- a review. Int J Pharm Bio Sci 2013; 4(4):9-13.
[31]	Janne Tiigimae-Saar, Edvitar Leibur, Tiia Tamme The effect of prednisolone on reduction of complaints after impacted third molar removal. Stomatologija, Baltic Dental and Maxillofacial Journal, 12: 17-22, 2010.
[32]	Warraich R, Faisal M, Rana M, et al. Evaluation of postoperative discomfort following third molar surgery using submucosal dexamethasone - Oral Surg Oral Med Oral Pathol Oral Radiol. 2013; 116(1):16-22.
[33]	Francisco Javier Herrera-Briones, Estrella Prados Sánchez, Candela Reyes Botella, et al. work on Update on the use of corticosteroids in third molar surgery. (Oral Surg Oral Med Oral Pathol Oral Radiol 2013;116:e342-e351).
[34]	Alcaˆntara, S. G. M. Falci, F. Oliveira-Ferreira, et al. comparative study of effect of dexamethasone vs methylprednisolone40mg on postoperative complication of surgical removal of lower third molar. Pinheiro 2013.
[35]	Sortino F, Cicciù, analyzed publications of the last 20 years with a pubmed search, focused on corticosteroid was administered by various routes Dent Res J (Isfahan). 2011 Oct; 8(4):162-71. doi: 10.4103/1735-3327.86031. M.

Cite This Article

Plain Text BibTeX RIS

APA Style

Ahmed Mohamed El Zayat, Eman Abdelhalem El Sharrawy, Amr Ali El Swify, Abdel Bade Abd Allah Abdel Maabod. (2018). Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar. International Journal of Clinical Oral and Maxillofacial Surgery, 4(1), 19-24. https://doi.org/10.11648/j.ijcoms.20180401.14

Copy | Download

ACS Style

Ahmed Mohamed El Zayat; Eman Abdelhalem El Sharrawy; Amr Ali El Swify; Abdel Bade Abd Allah Abdel Maabod. Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar. Int. J. Clin. Oral Maxillofac. Surg. 2018, 4(1), 19-24. doi: 10.11648/j.ijcoms.20180401.14

Copy | Download

AMA Style

Ahmed Mohamed El Zayat, Eman Abdelhalem El Sharrawy, Amr Ali El Swify, Abdel Bade Abd Allah Abdel Maabod. Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar. Int J Clin Oral Maxillofac Surg. 2018;4(1):19-24. doi: 10.11648/j.ijcoms.20180401.14

Copy | Download

@article{10.11648/j.ijcoms.20180401.14,
  author = {Ahmed Mohamed El Zayat and Eman Abdelhalem El Sharrawy and Amr Ali El Swify and Abdel Bade Abd Allah Abdel Maabod},
  title = {Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {4},
  number = {1},
  pages = {19-24},
  doi = {10.11648/j.ijcoms.20180401.14},
  url = {https://doi.org/10.11648/j.ijcoms.20180401.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20180401.14},
  abstract = {The aim of this comparative clinical study was to investigate the effects of preoperative injections of Dexamethasone Sodium Phosphate versus Diclofenac Sodium. The study includes 60 patients (age range 16-35) who were randomly distributed into three equal groups. Edema and trismus was measured preoperatively, immediate, 24 h, 2 week, 1 month postoperatively. Pain was assessed by visual analogue scale. Noteworthy reduction in postoperatively complication associated with Dexamethasone group was noticed. Edema & trismus in control group was greater followed by Diclofenac groups then group I. Pain was greater score in control group followed by Diclofenac group then group I.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar
AU  - Ahmed Mohamed El Zayat
AU  - Eman Abdelhalem El Sharrawy
AU  - Amr Ali El Swify
AU  - Abdel Bade Abd Allah Abdel Maabod
Y1  - 2018/06/02
PY  - 2018
N1  - https://doi.org/10.11648/j.ijcoms.20180401.14
DO  - 10.11648/j.ijcoms.20180401.14
T2  - International Journal of Clinical Oral and Maxillofacial Surgery
JF  - International Journal of Clinical Oral and Maxillofacial Surgery
JO  - International Journal of Clinical Oral and Maxillofacial Surgery
SP  - 19
EP  - 24
PB  - Science Publishing Group
SN  - 2472-1344
UR  - https://doi.org/10.11648/j.ijcoms.20180401.14
AB  - The aim of this comparative clinical study was to investigate the effects of preoperative injections of Dexamethasone Sodium Phosphate versus Diclofenac Sodium. The study includes 60 patients (age range 16-35) who were randomly distributed into three equal groups. Edema and trismus was measured preoperatively, immediate, 24 h, 2 week, 1 month postoperatively. Pain was assessed by visual analogue scale. Noteworthy reduction in postoperatively complication associated with Dexamethasone group was noticed. Edema & trismus in control group was greater followed by Diclofenac groups then group I. Pain was greater score in control group followed by Diclofenac group then group I.
VL  - 4
IS  - 1
ER  -

Copy | Download

Author Information

Ahmed Mohamed El Zayat

Oral & Maxillofacial Surgery Department, Insurance Hospital, Suez, Egypt
Eman Abdelhalem El Sharrawy

Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt
Amr Ali El Swify

Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt
Abdel Bade Abd Allah Abdel Maabod

Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Ahmed Mohamed El Zayat, Eman Abdelhalem El Sharrawy, Amr Ali El Swify, Abdel Bade Abd Allah Abdel Maabod. (2018). Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar. International Journal of Clinical Oral and Maxillofacial Surgery, 4(1), 19-24. https://doi.org/10.11648/j.ijcoms.20180401.14

Copy | Download

ACS Style

Ahmed Mohamed El Zayat; Eman Abdelhalem El Sharrawy; Amr Ali El Swify; Abdel Bade Abd Allah Abdel Maabod. Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar. Int. J. Clin. Oral Maxillofac. Surg. 2018, 4(1), 19-24. doi: 10.11648/j.ijcoms.20180401.14

Copy | Download

AMA Style

Ahmed Mohamed El Zayat, Eman Abdelhalem El Sharrawy, Amr Ali El Swify, Abdel Bade Abd Allah Abdel Maabod. Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar. Int J Clin Oral Maxillofac Surg. 2018;4(1):19-24. doi: 10.11648/j.ijcoms.20180401.14

Copy | Download

@article{10.11648/j.ijcoms.20180401.14,
  author = {Ahmed Mohamed El Zayat and Eman Abdelhalem El Sharrawy and Amr Ali El Swify and Abdel Bade Abd Allah Abdel Maabod},
  title = {Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {4},
  number = {1},
  pages = {19-24},
  doi = {10.11648/j.ijcoms.20180401.14},
  url = {https://doi.org/10.11648/j.ijcoms.20180401.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20180401.14},
  abstract = {The aim of this comparative clinical study was to investigate the effects of preoperative injections of Dexamethasone Sodium Phosphate versus Diclofenac Sodium. The study includes 60 patients (age range 16-35) who were randomly distributed into three equal groups. Edema and trismus was measured preoperatively, immediate, 24 h, 2 week, 1 month postoperatively. Pain was assessed by visual analogue scale. Noteworthy reduction in postoperatively complication associated with Dexamethasone group was noticed. Edema & trismus in control group was greater followed by Diclofenac groups then group I. Pain was greater score in control group followed by Diclofenac group then group I.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Comparative Clinical Study of Local Submucosal Corticosteriod Versus Diclofenac Sodium Injections Before Odontectomy of Mandibular Impacted Third Molar
AU  - Ahmed Mohamed El Zayat
AU  - Eman Abdelhalem El Sharrawy
AU  - Amr Ali El Swify
AU  - Abdel Bade Abd Allah Abdel Maabod
Y1  - 2018/06/02
PY  - 2018
N1  - https://doi.org/10.11648/j.ijcoms.20180401.14
DO  - 10.11648/j.ijcoms.20180401.14
T2  - International Journal of Clinical Oral and Maxillofacial Surgery
JF  - International Journal of Clinical Oral and Maxillofacial Surgery
JO  - International Journal of Clinical Oral and Maxillofacial Surgery
SP  - 19
EP  - 24
PB  - Science Publishing Group
SN  - 2472-1344
UR  - https://doi.org/10.11648/j.ijcoms.20180401.14
AB  - The aim of this comparative clinical study was to investigate the effects of preoperative injections of Dexamethasone Sodium Phosphate versus Diclofenac Sodium. The study includes 60 patients (age range 16-35) who were randomly distributed into three equal groups. Edema and trismus was measured preoperatively, immediate, 24 h, 2 week, 1 month postoperatively. Pain was assessed by visual analogue scale. Noteworthy reduction in postoperatively complication associated with Dexamethasone group was noticed. Edema & trismus in control group was greater followed by Diclofenac groups then group I. Pain was greater score in control group followed by Diclofenac group then group I.
VL  - 4
IS  - 1
ER  -

Copy | Download