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Fibrodysplasia Ossificans Progressiva: A Review with Presentation of a Case with Temporomandibular Extra-Articular Ankylosis

Received: 31 January 2018     Accepted: 16 February 2018     Published: 19 March 2018
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Abstract

Fibrodysplasia Ossificans Progressiva (FOP) is a connective tissue disorder that progressively affects tendons, ligaments, aponeurosis, fasciae and muscles which undergo fibrous cell proliferation that progresses to mature bone. It has a prevalence of 1 case per 2 million habitants, having reported less than 1000 cases worldwide. In the maxillofacial region, it might originate extra-articular temporomandibular ankylosis by ossification of ligaments, muscles of the mastication, head and a neck muscles; the most commonly affected are the masseters and sternocleidomastoids. The purpose of this article is to review the Fibrodysplasia Ossificans Progressiva (FOP) and to present the case of a 12-year-old male patient with FOP that causes extra-articular temporomandibular ankylosis. There is no effective proven treatment or prevention and the life expectancy of these patients approaches the 40 years of age, so the management of patients with FOP must be performed with a multidisciplinary approach in which the various health professionals work in a coordinated and joint way to offer a better quality of life to these patients and thus better understand the progression of the disease.

Published in International Journal of Clinical Oral and Maxillofacial Surgery (Volume 4, Issue 1)
DOI 10.11648/j.ijcoms.20180401.12
Page(s) 4-10
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Fibrodysplasia Ossificans Progressiva, Myositis Ossificans Systemic, Munchmeyer's Disease, Extra-Articular Temporomandibular Ankylosis, Ankylosis of the Temporomandibular Joint

References
[1] Pignolo RJ, Shore EM and Kaplan FS. Fibrodysplasia ossificans progressiva: diagnosis, management, and therapeutic horizons. Pediatric endocrinology reviews 10 (02): 437-446, 2013.
[2] Morales-Piga A, Bachiller-Corral FJ and Sánchez-Duffhues G. ¿Es la «fibrodisplasia osificante progresiva» una enfermedad de origen vascular? Un modelo patogénico innovador. Reumatología Clínica 10 (6): 389-395, 2014.
[3] Kaplan FS, Le Merrer M, Glaser DL, Pignolo RJ, Goldsby RE, Kitterman JA and Shore EM. Fibrodysplasia ossificans progressiva. Best practice & research Clinical rheumatology, 22 (1): 191-205, 2008.
[4] Shore EM and Kaplan FS. Insights from a rare genetic disorder of extra-skeletal bone formation, fibrodysplasia ossificans progressiva (FOP). Bone, 43 (3): 427-433, 2008.
[5] Wiggins RL, Thurber D, Abramovitch K, Bouquot J and Vigneswaran N. Myositis ossificans circumscripta of the buccinator muscle: first report of a rare complication of mandibular third molar extraction. Journal of oral and maxillofacial surgery, 66 (9): 1959-1953, 2008.
[6] García-Serrano G, Sagüillo K, Almeida F, Núñez J and Picón M. Fibrodisplasia osificante progresiva: el papel del cirujano oral y maxilofacial. Experiencia en 2 casos. Revista Española de Cirugía Oral y Maxilofacial, 36 (2): 73-77, 2014.
[7] Herford AS and Boyne PJ. Ankylosis of the jaw in a patient with fibrodysplasia ossificans progressiva. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 96 (6): 680-684, 2003.
[8] Meij EH, Becking AG and Waal I. Fibrodysplasia ossificans progressiva. An unusual cause of restricted mandibular movement. Oral diseases, 12 (2): 204-207, 2006.
[9] Díaz-de la Torre J. Fibrodisplasia osificante progresiva. Reporte de un caso. Acta Ortopédica Mexicana, 26 (3): 192-196, 2012.
[10] Kaplan FS, Shore EM, Glaser DL and Emerson S. The medical management of fibrodysplasia ossificans progressiva: current treatment considerations. In Clin Proc intl clin consort FOP, 4: 1-100, 2011.
[11] Katagiri T. Recent topics in fibrodysplasia ossificans progressiva. Journal of Oral Biosciences, 54 (3): 119-123, 2012.
[12] Pignolo RJ, Shore EM and Kaplan FS. Fibrodysplasia ossificans progressiva: clinical and genetic aspects. Orphanet journal of rare diseases, 6 (1): 80, 2011.
[13] Hernández GS, Ruiz AM, Río MG, Fernandez AR, Lozano SO, Font CR and Elvira JL. Miositis osificante progresiva. Utilidad de la gammagrafía ósea. Revista Española de Medicina Nuclear, 24 (3): 195-198, 2005.
[14] Sendur OF and Gurer G. Severe limitation in jaw movement in a patient with fibrodysplasia ossificans progressiva: a case report. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics, 102 (3): 312-317, 2006.
[15] Luchetti W, Cohen RB, Hahn GV, Rocke DM, Helpin M, Zasloff M and Kaplan FS. Severe restriction in jaw movement after routine injection of local anesthetic in patients who have fibrodysplasia ossificans progressiva. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 81 (1): 21-25, 1996.
[16] Woolgar JA, Beirne JC and Triantafyllou A. Myositis ossificans traumatica of sternocleidomastoid muscle presenting as cervical lymph-node metastasis. International journal of oral and maxillofacial surgery, 24 (2): 170-173, 1995.
[17] Jayade B, Adirajaiah S, Vadera H, Kundalaswamy G, Sattur AP and Kalkur C. Myositis ossificans in medial, lateral pterygoid, and contralateral temporalis muscles: a rare case report. Oral surgery, oral medicine, oral pathology and oral radiology, 116 (4): 261-266, 2013.
[18] Mevio E, Rizzi L and Bernasconi G. Myositis ossificans traumatica of the temporal muscle: a case report. Auris Nasus Larynx, 28 (4): 345-347, 2001.
[19] Saka B, Stropahl G and Gundlach KKH. Traumatic myositis ossificans (ossifying pseudotumor) of temporal muscle. International journal of oral and maxillofacial surgery, 31 (1): 110-111, 2002.
[20] Aoki T, Naito H, Ota Y and Shiiki K. Myositis ossificans traumatica of the masticatory muscles: review of the literature and report of a case. Journal of oral and maxillofacial surgery, 60 (9): 1083-1088, 2002.
[21] Kim DD, Lazow SK, Har-El G and Berger JR. Myositis ossificans traumatica of masticatory musculature: a case report and literature review. Journal of oral and maxillofacial surgery, 60 (9): 1072-1076, 2002.
[22] Debeney-Bruyerre C, Chikhani L, Lockhart R, Favre-Dauvergne E, Weschler B, Bertrand JC and Guilbert F. Myositis ossificans progressiva: five generations where the disease was exclusively limited to the maxillofacial region: a case report. International journal of oral and maxillofacial surgery, 27 (4): 299-302, 1998.
[23] Kaplan FS, Groppe J and Shore EM. When one skeleton is enough: approaches and strategies for the treatment of fibrodysplasia ossificans progressiva (FOP). Drug Discovery Today: Therapeutic Strategies, 5 (4): 255-262, 2009.
[24] Lasry F, Touki A, Abkari A and Khalifa HH. A rare cause of painful cervical swelling: myositis ossificans progressiva in childhood. Report of a case. Joint bone spine, 72 (4): 335-337, 2005.
[25] Morales-Piga A, Bachiller-Corral J, Trujillo-Tiebas MJ, Villaverde-Hueso A, Gamir-Gamir ML, Alonso-Ferreira V and Ayuso-García C. Fibrodysplasia ossificans progressiva in Spain: epidemiological, clinical, and genetic aspects. Bone, 51 (4): 748-755, 2012.
[26] Gómez MDMM, Navarro MN, Santiago FR and Álvarez ER. Fibrodisplasia osificante progresiva: comunicación de un caso terminal. Reumatología Clínica, 2016. http://dx.doi.org/10.1016/j.reuma.2016.04.006.
[27] Bridges AJ, Hsu KC, Singh A, Churchill R and Miles J. Fibrodysplasia (myositis) ossificans progressiva. In Seminars in arthritis and rheumatism, 24 (3): 155-164, 1994.
[28] Carvalho DR, Farage L, Martins BJAF and Speck-Martins CE. Craniofacial findings in fibrodysplasia ossificans progressiva: computerized tomography evaluation. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 111 (4): 499-502, 2011.
[29] Rogers JG and Geho WB. Fibrodysplasia ossificans progressiva. A survey of forty-two cases. J Bone Joint Surg Am, 61 (6): 909-914, 1979.
[30] Marx RE and Stern D. Oral and Maxillofacial Pathology: A Rationale for Diagnosis and Treatment. Inflammatory and Reactive Diseases of the Oral and Maxillofacial Region. Myositis Ossificans Progressiva. 2nd Ed. China. Quintessence Publishing Co. 2012 Chap. 2. Pag. 36-41.
[31] Kriegbaum RK and Hillerup S. Fibrodysplasia ossificans progressiva (FOP): Report of a case with extra-articular ankylosis of the mandible. Journal of Cranio-Maxillofacial Surgery, 41 (8): 856-860, 2013.
[32] Duan Y, Zhang H and Bu R. Intraoral approach technique for treating trismus caused by fibrodysplasia ossificans progressiva. Journal of Oral and Maxillofacial Surgery, 68 (6): 1408-1410, 2010.
[33] Bar Oz B and Boneh A. Myositis ossificans progressiva: a 10‐year follow‐up on a patient treated with etidronate disodium. Acta Paediatrica, 83 (12): 1332-1334, 1994.
[34] Hildebrandt G, Seed MP, Freemantle CN et al. Mechanisms of the antiinflammatory activity of low-dose radiation therapy. Int J Radiat Biol, 74 (3): 367-378, 1998.
[35] Connor JM and Evans DAP. Extra-articular ankylosis in fibrodysplasia ossificans progressiva. British Journal of Oral Surgery, 20 (2): 117-121, 1982.
[36] Renton P, Parkin SF and Stamp TCB. Abnormal temporomandibular joints in fibrodysplasia ossificans progressiva. British Journal of Oral Surgery, 20 (1): 31-38, 1982.
[37] Sellami M, Kallel S, Kessentini A, Charfeddine I, Hammami B and Ghorbel A. Fibrodysplasia ossificans progressiva presenting as a painful swelling of the sternocleidomastoid muscle. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 27 (5): 690-692, 2015.
[38] Roberts T, Stephen L, Scott C, Urban M, Sudi S and Beighton P. Fibrodysplasia ossificans progressiva (FOP) in South Africa: dental implications in 5 cases. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 112 (1): 11-18, 2011.
[39] Singh A, Ayyalapu A and Keochekian A. Anesthetic management in fibrodysplasia ossificans progressiva (FOP): a case report. Journal of clinical anesthesia, 15 (3): 211-213, 2003.
[40] Nussbaum BL, Grunwald Z and Kaplan FS. Oral and dental health care and anesthesia for persons with fibrodysplasia ossificans progressiva. Clinical Reviews in Bone and Mineral Metabolism, 3 (3-4): 239-242, 2005.
[41] Young JM, Diecidue RJ and Nussbaum BL. Oral management in a patient with fibrodysplasia ossificans progressiva. Special Care in Dentistry, 27 (3): 101-104, 2007.
[42] Nussbaum BL. Dental care for patients who are unable to open their mouths. Dental Clinics of North America, 53 (2): 323-328, 2009.
[43] Shimono K, Uchibe K, Kuboki T and Iwamoto M. The pathophysiology of heterotopic ossification: Current treatment considerations in dentistry. Japanese Dental Science Review, 50 (1): 1-8, 2014.
[44] Janoff HB, Zasloff MA and Kaplan FS. Submandibular swelling in patients with fibrodysplasia ossificans progressiva. Otolaryngology-Head and Neck Surgery, 114 (4): 599-604, 1996.
[45] Leavitt BD, Teeples TJ and Viozzi CF. Submandibular space swelling in a patient with fibrodysplasia ossificans progressiva: a diagnostic dilemma. Journal of Oral and Maxillofacial Surgery, 67 (3): 668-673, 2009.
[46] Awais M, Rehman A and Baloch NUA. Fibrodysplasia Ossificans Progressiva Misdiagnosed as Cervical Exostosis. Internal Medicine, 54 (7): 867-868, 2015.
Cite This Article
  • APA Style

    Cárcamo Idiáquez Osmar Adán, Cortes Flores Michelle, Anchecta Castro Diana Marielos, Vivanco Pérez Israel, Navarro Zarate Adolfo. (2018). Fibrodysplasia Ossificans Progressiva: A Review with Presentation of a Case with Temporomandibular Extra-Articular Ankylosis. International Journal of Clinical Oral and Maxillofacial Surgery, 4(1), 4-10. https://doi.org/10.11648/j.ijcoms.20180401.12

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    ACS Style

    Cárcamo Idiáquez Osmar Adán; Cortes Flores Michelle; Anchecta Castro Diana Marielos; Vivanco Pérez Israel; Navarro Zarate Adolfo. Fibrodysplasia Ossificans Progressiva: A Review with Presentation of a Case with Temporomandibular Extra-Articular Ankylosis. Int. J. Clin. Oral Maxillofac. Surg. 2018, 4(1), 4-10. doi: 10.11648/j.ijcoms.20180401.12

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    AMA Style

    Cárcamo Idiáquez Osmar Adán, Cortes Flores Michelle, Anchecta Castro Diana Marielos, Vivanco Pérez Israel, Navarro Zarate Adolfo. Fibrodysplasia Ossificans Progressiva: A Review with Presentation of a Case with Temporomandibular Extra-Articular Ankylosis. Int J Clin Oral Maxillofac Surg. 2018;4(1):4-10. doi: 10.11648/j.ijcoms.20180401.12

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  • @article{10.11648/j.ijcoms.20180401.12,
      author = {Cárcamo Idiáquez Osmar Adán and Cortes Flores Michelle and Anchecta Castro Diana Marielos and Vivanco Pérez Israel and Navarro Zarate Adolfo},
      title = {Fibrodysplasia Ossificans Progressiva: A Review with Presentation of a Case with Temporomandibular Extra-Articular Ankylosis},
      journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
      volume = {4},
      number = {1},
      pages = {4-10},
      doi = {10.11648/j.ijcoms.20180401.12},
      url = {https://doi.org/10.11648/j.ijcoms.20180401.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20180401.12},
      abstract = {Fibrodysplasia Ossificans Progressiva (FOP) is a connective tissue disorder that progressively affects tendons, ligaments, aponeurosis, fasciae and muscles which undergo fibrous cell proliferation that progresses to mature bone. It has a prevalence of 1 case per 2 million habitants, having reported less than 1000 cases worldwide. In the maxillofacial region, it might originate extra-articular temporomandibular ankylosis by ossification of ligaments, muscles of the mastication, head and a neck muscles; the most commonly affected are the masseters and sternocleidomastoids. The purpose of this article is to review the Fibrodysplasia Ossificans Progressiva (FOP) and to present the case of a 12-year-old male patient with FOP that causes extra-articular temporomandibular ankylosis. There is no effective proven treatment or prevention and the life expectancy of these patients approaches the 40 years of age, so the management of patients with FOP must be performed with a multidisciplinary approach in which the various health professionals work in a coordinated and joint way to offer a better quality of life to these patients and thus better understand the progression of the disease.},
     year = {2018}
    }
    

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    JF  - International Journal of Clinical Oral and Maxillofacial Surgery
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    AB  - Fibrodysplasia Ossificans Progressiva (FOP) is a connective tissue disorder that progressively affects tendons, ligaments, aponeurosis, fasciae and muscles which undergo fibrous cell proliferation that progresses to mature bone. It has a prevalence of 1 case per 2 million habitants, having reported less than 1000 cases worldwide. In the maxillofacial region, it might originate extra-articular temporomandibular ankylosis by ossification of ligaments, muscles of the mastication, head and a neck muscles; the most commonly affected are the masseters and sternocleidomastoids. The purpose of this article is to review the Fibrodysplasia Ossificans Progressiva (FOP) and to present the case of a 12-year-old male patient with FOP that causes extra-articular temporomandibular ankylosis. There is no effective proven treatment or prevention and the life expectancy of these patients approaches the 40 years of age, so the management of patients with FOP must be performed with a multidisciplinary approach in which the various health professionals work in a coordinated and joint way to offer a better quality of life to these patients and thus better understand the progression of the disease.
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Author Information
  • Maxillofacial Surgery Department, Meritorious Autonomous University of Puebla, Puebla, Mexico

  • Maxillofacial Surgery Department, Mexican Institute of Social Security, Guadalajara, Mexico

  • Faculty of Stomatology, Meritorious Autonomous University of Puebla, Puebla, Mexico

  • Maxillofacial Surgery Department, Meritorious Autonomous University of Puebla, Puebla, Mexico

  • Maxillofacial Surgery Department, Meritorious Autonomous University of Puebla, Puebla, Mexico

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