Artemisia argyi is a well-known medicinal plant which has been used in traditional Chinese medicine for thousands of years. It is usually named Aicao or Aihao in China, and the leaves are processed and applied in moxibustion to treat different kinds of diseases. In order to select the best germplasm resource to grow high quality herbal products, we have compared the HPLC fingerprints profiles of 52 geographically different germplasm resources collected from 17 provinces of China. The results data were processed by similarity and hierarchical clustering analyses. In addition, common patterns of a typical local variety of A. argyi sourced in Henan province are established, and sample similarities were evaluated by selection of 14 typical chromatographic peaks of 10 samples and are found to vary between 0.664 and 0.969. The results show that the HPLC fngerprint analysis and quantitative analysis is a powerful tool to identify and control the quality of fresh A. argyi and related products. In addition, the content of a major secondary metabolite in the leaves of A. argyi known as eupatilin, which is a flavone with numerous bioactivities such as anticancer, anti-inflammation and anti ulcer has been determined for all the 52 samples by HPLC-DAD. The results provided great scientific basis for the research and development of the herb as popular products for the health care of human beings.
Published in | International Journal of Chinese Medicine (Volume 5, Issue 3) |
DOI | 10.11648/j.ijcm.20210503.11 |
Page(s) | 38-47 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
HPLC, Fingerprints, Eupatilin, Content
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APA Style
Hankui Wu, Xingqiang Gao, Xinyong You, Jianguang Chen, Zhen Su, et al. (2021). Eupatilin Content and HPLC Fingerprints of Fresh Leaves of Artemisia argyi from 52 Germplasm Resources. International Journal of Chinese Medicine, 5(3), 38-47. https://doi.org/10.11648/j.ijcm.20210503.11
ACS Style
Hankui Wu; Xingqiang Gao; Xinyong You; Jianguang Chen; Zhen Su, et al. Eupatilin Content and HPLC Fingerprints of Fresh Leaves of Artemisia argyi from 52 Germplasm Resources. Int. J. Chin. Med. 2021, 5(3), 38-47. doi: 10.11648/j.ijcm.20210503.11
AMA Style
Hankui Wu, Xingqiang Gao, Xinyong You, Jianguang Chen, Zhen Su, et al. Eupatilin Content and HPLC Fingerprints of Fresh Leaves of Artemisia argyi from 52 Germplasm Resources. Int J Chin Med. 2021;5(3):38-47. doi: 10.11648/j.ijcm.20210503.11
@article{10.11648/j.ijcm.20210503.11, author = {Hankui Wu and Xingqiang Gao and Xinyong You and Jianguang Chen and Zhen Su and Yuanping Wang and Kunpeng Zhang and Linlin Hou}, title = {Eupatilin Content and HPLC Fingerprints of Fresh Leaves of Artemisia argyi from 52 Germplasm Resources}, journal = {International Journal of Chinese Medicine}, volume = {5}, number = {3}, pages = {38-47}, doi = {10.11648/j.ijcm.20210503.11}, url = {https://doi.org/10.11648/j.ijcm.20210503.11}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20210503.11}, abstract = {Artemisia argyi is a well-known medicinal plant which has been used in traditional Chinese medicine for thousands of years. It is usually named Aicao or Aihao in China, and the leaves are processed and applied in moxibustion to treat different kinds of diseases. In order to select the best germplasm resource to grow high quality herbal products, we have compared the HPLC fingerprints profiles of 52 geographically different germplasm resources collected from 17 provinces of China. The results data were processed by similarity and hierarchical clustering analyses. In addition, common patterns of a typical local variety of A. argyi sourced in Henan province are established, and sample similarities were evaluated by selection of 14 typical chromatographic peaks of 10 samples and are found to vary between 0.664 and 0.969. The results show that the HPLC fngerprint analysis and quantitative analysis is a powerful tool to identify and control the quality of fresh A. argyi and related products. In addition, the content of a major secondary metabolite in the leaves of A. argyi known as eupatilin, which is a flavone with numerous bioactivities such as anticancer, anti-inflammation and anti ulcer has been determined for all the 52 samples by HPLC-DAD. The results provided great scientific basis for the research and development of the herb as popular products for the health care of human beings.}, year = {2021} }
TY - JOUR T1 - Eupatilin Content and HPLC Fingerprints of Fresh Leaves of Artemisia argyi from 52 Germplasm Resources AU - Hankui Wu AU - Xingqiang Gao AU - Xinyong You AU - Jianguang Chen AU - Zhen Su AU - Yuanping Wang AU - Kunpeng Zhang AU - Linlin Hou Y1 - 2021/07/24 PY - 2021 N1 - https://doi.org/10.11648/j.ijcm.20210503.11 DO - 10.11648/j.ijcm.20210503.11 T2 - International Journal of Chinese Medicine JF - International Journal of Chinese Medicine JO - International Journal of Chinese Medicine SP - 38 EP - 47 PB - Science Publishing Group SN - 2578-9473 UR - https://doi.org/10.11648/j.ijcm.20210503.11 AB - Artemisia argyi is a well-known medicinal plant which has been used in traditional Chinese medicine for thousands of years. It is usually named Aicao or Aihao in China, and the leaves are processed and applied in moxibustion to treat different kinds of diseases. In order to select the best germplasm resource to grow high quality herbal products, we have compared the HPLC fingerprints profiles of 52 geographically different germplasm resources collected from 17 provinces of China. The results data were processed by similarity and hierarchical clustering analyses. In addition, common patterns of a typical local variety of A. argyi sourced in Henan province are established, and sample similarities were evaluated by selection of 14 typical chromatographic peaks of 10 samples and are found to vary between 0.664 and 0.969. The results show that the HPLC fngerprint analysis and quantitative analysis is a powerful tool to identify and control the quality of fresh A. argyi and related products. In addition, the content of a major secondary metabolite in the leaves of A. argyi known as eupatilin, which is a flavone with numerous bioactivities such as anticancer, anti-inflammation and anti ulcer has been determined for all the 52 samples by HPLC-DAD. The results provided great scientific basis for the research and development of the herb as popular products for the health care of human beings. VL - 5 IS - 3 ER -