Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction

Jiang Yiming; Jiang Xuelian; Zou Yong; Wang Huikai; Lu Yuliang

doi:doi:10.11648/j.ijcm.20190304.12

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Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction

Jiang Yiming, Jiang Xuelian, Zou Yong, Wang Huikai, Lu Yuliang

Published in International Journal of Chinese Medicine (Volume 3, Issue 4)

Received: 13 October 2019 Accepted: 9 November 2019 Published: 17 November 2019

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Abstract

Objective: Chronic severe intrahepatic cholestasis hepatitis is a clinical refractory disease. We have achieved good results in the treatment of chronic severe intrahepatic cholestasis hepatitis with Liu Chen Tang. This study aims to explore the clinical efficacy of Liu Chen Tang in the treatment of chronic severe intrahepatic cholestasis hepatitis. Methods: Thirty-five patients with chronic severe intrahepatic cholestatic hepatitis were randomly divided into Chinese medicine treatment group (n=23) and control group (n=12). The changes of symptoms, signs such as yellow eyes and body, fatigue, nausea, low food intake, and yellow urine and liver function including serum total bilirubin (TBIL), direct bilirubin (DBIL), alanine aminotransferase (ALT), γ-glutamyl peptide transferase (GGT), before and after treatment were observed. Results: The improvement of the above indicators in the treatment group was significantly better than that of the control group (P<0.01 or P<0.05). The effective rate of the treatment group was 95.6%, and the effective rate of the control group was 58.3%. Conclusion: Through the application of Liu Xi Decoction in the treatment of chronic severe intrahepatic cholestatic hepatitis, it was observed that the treatment group was significantly better than the control group. Liu Xi Decoction is an effective prescription for the treatment of chronic severe intrahepatic cholestatic hepatitis and is worthy of further popularization and application.

Published in	International Journal of Chinese Medicine (Volume 3, Issue 4)
DOI	10.11648/j.ijcm.20190304.12
Page(s)	59-63
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Liu Xi Decoction, Chronic Severe Cholestatic Hepatitis, Clinical Research

References

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[2]	Jiang Xuelian, Zhang Guodong, Sun Yunting, Wei Ming, Yang Jichao, Liu Zhixue. Clinical study of Liu Xi Decoction in the treatment of chronic severe intrahepatic cholestatic hepatitis [J]. Chinese medical emergencies, 2008 (09): 1217-1218.
[3]	Chinese Medical Association Infectious Diseases and Parasitic Diseases Branch, Liver Diseases Branch. Diagnostic criteria for viral hepatitis [J]. Chinese Journal of Integrated Traditional and Western Medicine, 2001, 11 (1): 56-60
[4]	Wang Guiqiang, Wang Fusheng, Cheng Jun, Ren Hong, Zhuang Hui, Sun Jian, Li Lanjuan, Li Jie, Meng Qinghua, Zhao Jingmin, Duan Zhongping, Hou Jinlin, Jia Jidong, Tang Hong, Sheng Jifang, Peng Yu, Lu Fengmin, Xie Qing, Wei Come. Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2015 Edition) [J]. Journal of Practical Hepatology, 2016, 19 (03): 389-400.
[5]	Huang Dawei, Ye Chunsheng, Wang Xiaodong. Observation on the efficacy of reusing blood circulation and removing blood stasis combined with western medicine in the treatment of refractory jaundice [J]. Hubei Journal of Traditional Chinese Medicine, 2017, 39 (07): 25-26.
[6]	Jiang Yiming, Jiang Xuelian, Liu Xinjun et al. Study on the optimization of liver fibrosis in patients with chronic hepatitis B treated by traditional Chinese medicine [J]. World Journal of Integrated Traditional Chinese and Western Medicine, 2015, 10 (01): 75-77.
[7]	Jiang Yiming, Jiang Xuelian, Wang Huikai et al. Clinical study of Liu Xiaoyao Wuqi Decoction in the treatment of chronic hepatitis B liver fibrosis [J]. Modern Journal of Integrated Traditional Chinese and Western Medicine, 2016, 25 (24): 2655-2657.
[8]	Jia Jianying, Lu Yuliang, Wang Huikai, Jiang Xuelian. Professor Jiang Xuelian's treatment of hepatitis B virus [J]. Shanxi Chinese Medicine, 2018, 39 (09): 1301-1303.
[9]	Zhou Houqin, Zhang Wei, Lu Xiaohua, Yang Yuxue, Wang Yingying, Zhao Yanling. Research progress in the treatment of cholestatic hepatitis with traditional Chinese medicine [J]. Evaluation and analysis of drug use in hospitals in China, 2018, 18 (12): 1588-1590+1594.
[10]	Wan Wanxiang, Wang Daguang, Shi Jia, Chen Hongkuan, Deng Linlin. Effect of Integrative Chinese and Western Medicine on Cholestatic Hepatitis [J]. Shanxi Journal of Traditional Chinese Medicine, 2017, 33 (07): 20+25.
[11]	Ji Yang, Guo Mingxing. Treatment of 38 cases of chronic type B cholestatic hepatitis with Ligan Huihuang Mixture [J]. Journal of Integrated Traditional and Western Medicine on Liver Diseases, 2018, 28 (03): 180-181.
[12]	Wang Chengbai. Diagnosis and treatment of chronic severe hepatitis with integrated traditional Chinese and Western medicine [M]. Hebei Zhengding: Handout of the Second National Advanced Chinese and Western Medicine Treatment of Hepatic Diseases, 2003, 35-51
[13]	Yan Ying, Song Maozhou, Liang Chaorong. Clinical observation of adenosylmethionine combined with ursodeoxycholic acid in the treatment of chronic severe cholestatic hepatitis B [J]. Journal of Shanxi College of Traditional Chinese Medicine, 2013, 14 (03): 68-69.
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APA Style

Jiang Yiming, Jiang Xuelian, Zou Yong, Wang Huikai, Lu Yuliang. (2019). Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction. International Journal of Chinese Medicine, 3(4), 59-63. https://doi.org/10.11648/j.ijcm.20190304.12

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ACS Style

Jiang Yiming; Jiang Xuelian; Zou Yong; Wang Huikai; Lu Yuliang. Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction. Int. J. Chin. Med. 2019, 3(4), 59-63. doi: 10.11648/j.ijcm.20190304.12

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AMA Style

Jiang Yiming, Jiang Xuelian, Zou Yong, Wang Huikai, Lu Yuliang. Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction. Int J Chin Med. 2019;3(4):59-63. doi: 10.11648/j.ijcm.20190304.12

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@article{10.11648/j.ijcm.20190304.12,
  author = {Jiang Yiming and Jiang Xuelian and Zou Yong and Wang Huikai and Lu Yuliang},
  title = {Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction},
  journal = {International Journal of Chinese Medicine},
  volume = {3},
  number = {4},
  pages = {59-63},
  doi = {10.11648/j.ijcm.20190304.12},
  url = {https://doi.org/10.11648/j.ijcm.20190304.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20190304.12},
  abstract = {Objective: Chronic severe intrahepatic cholestasis hepatitis is a clinical refractory disease. We have achieved good results in the treatment of chronic severe intrahepatic cholestasis hepatitis with Liu Chen Tang. This study aims to explore the clinical efficacy of Liu Chen Tang in the treatment of chronic severe intrahepatic cholestasis hepatitis. Methods: Thirty-five patients with chronic severe intrahepatic cholestatic hepatitis were randomly divided into Chinese medicine treatment group (n=23) and control group (n=12). The changes of symptoms, signs such as yellow eyes and body, fatigue, nausea, low food intake, and yellow urine and liver function including serum total bilirubin (TBIL), direct bilirubin (DBIL), alanine aminotransferase (ALT), γ-glutamyl peptide transferase (GGT), before and after treatment were observed. Results: The improvement of the above indicators in the treatment group was significantly better than that of the control group (P<0.01 or P<0.05). The effective rate of the treatment group was 95.6%, and the effective rate of the control group was 58.3%. Conclusion: Through the application of Liu Xi Decoction in the treatment of chronic severe intrahepatic cholestatic hepatitis, it was observed that the treatment group was significantly better than the control group. Liu Xi Decoction is an effective prescription for the treatment of chronic severe intrahepatic cholestatic hepatitis and is worthy of further popularization and application.},
 year = {2019}
}

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TY  - JOUR
T1  - Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction
AU  - Jiang Yiming
AU  - Jiang Xuelian
AU  - Zou Yong
AU  - Wang Huikai
AU  - Lu Yuliang
Y1  - 2019/11/17
PY  - 2019
N1  - https://doi.org/10.11648/j.ijcm.20190304.12
DO  - 10.11648/j.ijcm.20190304.12
T2  - International Journal of Chinese Medicine
JF  - International Journal of Chinese Medicine
JO  - International Journal of Chinese Medicine
SP  - 59
EP  - 63
PB  - Science Publishing Group
SN  - 2578-9473
UR  - https://doi.org/10.11648/j.ijcm.20190304.12
AB  - Objective: Chronic severe intrahepatic cholestasis hepatitis is a clinical refractory disease. We have achieved good results in the treatment of chronic severe intrahepatic cholestasis hepatitis with Liu Chen Tang. This study aims to explore the clinical efficacy of Liu Chen Tang in the treatment of chronic severe intrahepatic cholestasis hepatitis. Methods: Thirty-five patients with chronic severe intrahepatic cholestatic hepatitis were randomly divided into Chinese medicine treatment group (n=23) and control group (n=12). The changes of symptoms, signs such as yellow eyes and body, fatigue, nausea, low food intake, and yellow urine and liver function including serum total bilirubin (TBIL), direct bilirubin (DBIL), alanine aminotransferase (ALT), γ-glutamyl peptide transferase (GGT), before and after treatment were observed. Results: The improvement of the above indicators in the treatment group was significantly better than that of the control group (P<0.01 or P<0.05). The effective rate of the treatment group was 95.6%, and the effective rate of the control group was 58.3%. Conclusion: Through the application of Liu Xi Decoction in the treatment of chronic severe intrahepatic cholestatic hepatitis, it was observed that the treatment group was significantly better than the control group. Liu Xi Decoction is an effective prescription for the treatment of chronic severe intrahepatic cholestatic hepatitis and is worthy of further popularization and application.
VL  - 3
IS  - 4
ER  -

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Author Information

Jiang Yiming

Basic Medical College, Qingdao University, Qingdao, China
Jiang Xuelian

Affiliated Hospital of Binzhou Medical Colleg, Binzhou, China
Zou Yong

Yantai Yuhuangding Hospital, Yantai, China
Wang Huikai

Affiliated Hospital of Binzhou Medical Colleg, Binzhou, China
Lu Yuliang

Affiliated Hospital of Binzhou Medical Colleg, Binzhou, China

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Plain Text BibTeX RIS

APA Style

Jiang Yiming, Jiang Xuelian, Zou Yong, Wang Huikai, Lu Yuliang. (2019). Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction. International Journal of Chinese Medicine, 3(4), 59-63. https://doi.org/10.11648/j.ijcm.20190304.12

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ACS Style

Jiang Yiming; Jiang Xuelian; Zou Yong; Wang Huikai; Lu Yuliang. Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction. Int. J. Chin. Med. 2019, 3(4), 59-63. doi: 10.11648/j.ijcm.20190304.12

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AMA Style

Jiang Yiming, Jiang Xuelian, Zou Yong, Wang Huikai, Lu Yuliang. Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction. Int J Chin Med. 2019;3(4):59-63. doi: 10.11648/j.ijcm.20190304.12

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@article{10.11648/j.ijcm.20190304.12,
  author = {Jiang Yiming and Jiang Xuelian and Zou Yong and Wang Huikai and Lu Yuliang},
  title = {Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction},
  journal = {International Journal of Chinese Medicine},
  volume = {3},
  number = {4},
  pages = {59-63},
  doi = {10.11648/j.ijcm.20190304.12},
  url = {https://doi.org/10.11648/j.ijcm.20190304.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20190304.12},
  abstract = {Objective: Chronic severe intrahepatic cholestasis hepatitis is a clinical refractory disease. We have achieved good results in the treatment of chronic severe intrahepatic cholestasis hepatitis with Liu Chen Tang. This study aims to explore the clinical efficacy of Liu Chen Tang in the treatment of chronic severe intrahepatic cholestasis hepatitis. Methods: Thirty-five patients with chronic severe intrahepatic cholestatic hepatitis were randomly divided into Chinese medicine treatment group (n=23) and control group (n=12). The changes of symptoms, signs such as yellow eyes and body, fatigue, nausea, low food intake, and yellow urine and liver function including serum total bilirubin (TBIL), direct bilirubin (DBIL), alanine aminotransferase (ALT), γ-glutamyl peptide transferase (GGT), before and after treatment were observed. Results: The improvement of the above indicators in the treatment group was significantly better than that of the control group (P<0.01 or P<0.05). The effective rate of the treatment group was 95.6%, and the effective rate of the control group was 58.3%. Conclusion: Through the application of Liu Xi Decoction in the treatment of chronic severe intrahepatic cholestatic hepatitis, it was observed that the treatment group was significantly better than the control group. Liu Xi Decoction is an effective prescription for the treatment of chronic severe intrahepatic cholestatic hepatitis and is worthy of further popularization and application.},
 year = {2019}
}

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TY  - JOUR
T1  - Clinical Study on Treatment of Chronic Severe Intrahepatic Cholestatic Hepatitis with Liu Xi Decoction
AU  - Jiang Yiming
AU  - Jiang Xuelian
AU  - Zou Yong
AU  - Wang Huikai
AU  - Lu Yuliang
Y1  - 2019/11/17
PY  - 2019
N1  - https://doi.org/10.11648/j.ijcm.20190304.12
DO  - 10.11648/j.ijcm.20190304.12
T2  - International Journal of Chinese Medicine
JF  - International Journal of Chinese Medicine
JO  - International Journal of Chinese Medicine
SP  - 59
EP  - 63
PB  - Science Publishing Group
SN  - 2578-9473
UR  - https://doi.org/10.11648/j.ijcm.20190304.12
AB  - Objective: Chronic severe intrahepatic cholestasis hepatitis is a clinical refractory disease. We have achieved good results in the treatment of chronic severe intrahepatic cholestasis hepatitis with Liu Chen Tang. This study aims to explore the clinical efficacy of Liu Chen Tang in the treatment of chronic severe intrahepatic cholestasis hepatitis. Methods: Thirty-five patients with chronic severe intrahepatic cholestatic hepatitis were randomly divided into Chinese medicine treatment group (n=23) and control group (n=12). The changes of symptoms, signs such as yellow eyes and body, fatigue, nausea, low food intake, and yellow urine and liver function including serum total bilirubin (TBIL), direct bilirubin (DBIL), alanine aminotransferase (ALT), γ-glutamyl peptide transferase (GGT), before and after treatment were observed. Results: The improvement of the above indicators in the treatment group was significantly better than that of the control group (P<0.01 or P<0.05). The effective rate of the treatment group was 95.6%, and the effective rate of the control group was 58.3%. Conclusion: Through the application of Liu Xi Decoction in the treatment of chronic severe intrahepatic cholestatic hepatitis, it was observed that the treatment group was significantly better than the control group. Liu Xi Decoction is an effective prescription for the treatment of chronic severe intrahepatic cholestatic hepatitis and is worthy of further popularization and application.
VL  - 3
IS  - 4
ER  -

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