Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian

Olusegun Adesola Busari; Paul Olowoyo; Segun Oladele Adeniyi; Bidemi Olayemi Onipede; Olisa Joseph; Solomon Ogunniran

doi:doi:10.11648/j.cnn.20180202.11

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Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian

Olusegun Adesola Busari, Paul Olowoyo, Segun Oladele Adeniyi, Bidemi Olayemi Onipede, Olisa Joseph, Solomon Ogunniran

Published in Clinical Neurology and Neuroscience (Volume 2, Issue 2)

Received: 25 October 2017 Accepted: 3 February 2018 Published: 4 July 2018

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Abstract

Dopa-responsive dystonia, also known as hereditary progressive dystonia with diurnal variation, is a genetic disease characterized by childhood or adolescent onset of dystonia and sometimes associated with parkinsonian features. This is a case report of an 18 year old Nigerian University undergraduate with features of difficulty in speaking, stiffness of the body, gait difficulties, coarse tremors and toe-walking. There was a very marked improvement of symptoms and signs within 24-48 hours of the commencement of SinemetTM (levodopa/ carbidopa) 125mg/12.5mg daily. The patient was discharged after 5 days with normal gait.

Published in	Clinical Neurology and Neuroscience (Volume 2, Issue 2)
DOI	10.11648/j.cnn.20180202.11
Page(s)	23-26
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Dopa, Dystonia, Diurnal Variations, Levodopa/Carbidopa

References

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APA Style

Olusegun Adesola Busari, Paul Olowoyo, Segun Oladele Adeniyi, Bidemi Olayemi Onipede, Olisa Joseph, et al. (2018). Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian. Clinical Neurology and Neuroscience, 2(2), 23-26. https://doi.org/10.11648/j.cnn.20180202.11

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ACS Style

Olusegun Adesola Busari; Paul Olowoyo; Segun Oladele Adeniyi; Bidemi Olayemi Onipede; Olisa Joseph, et al. Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian. Clin. Neurol. Neurosci. 2018, 2(2), 23-26. doi: 10.11648/j.cnn.20180202.11

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AMA Style

Olusegun Adesola Busari, Paul Olowoyo, Segun Oladele Adeniyi, Bidemi Olayemi Onipede, Olisa Joseph, et al. Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian. Clin Neurol Neurosci. 2018;2(2):23-26. doi: 10.11648/j.cnn.20180202.11

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@article{10.11648/j.cnn.20180202.11,
  author = {Olusegun Adesola Busari and Paul Olowoyo and Segun Oladele Adeniyi and Bidemi Olayemi Onipede and Olisa Joseph and Solomon Ogunniran},
  title = {Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian},
  journal = {Clinical Neurology and Neuroscience},
  volume = {2},
  number = {2},
  pages = {23-26},
  doi = {10.11648/j.cnn.20180202.11},
  url = {https://doi.org/10.11648/j.cnn.20180202.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20180202.11},
  abstract = {Dopa-responsive dystonia, also known as hereditary progressive dystonia with diurnal variation, is a genetic disease characterized by childhood or adolescent onset of dystonia and sometimes associated with parkinsonian features. This is a case report of an 18 year old Nigerian University undergraduate with features of difficulty in speaking, stiffness of the body, gait difficulties, coarse tremors and toe-walking. There was a very marked improvement of symptoms and signs within 24-48 hours of the commencement of SinemetTM (levodopa/ carbidopa) 125mg/12.5mg daily. The patient was discharged after 5 days with normal gait.},
 year = {2018}
}

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TY  - JOUR
T1  - Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian
AU  - Olusegun Adesola Busari
AU  - Paul Olowoyo
AU  - Segun Oladele Adeniyi
AU  - Bidemi Olayemi Onipede
AU  - Olisa Joseph
AU  - Solomon Ogunniran
Y1  - 2018/07/04
PY  - 2018
N1  - https://doi.org/10.11648/j.cnn.20180202.11
DO  - 10.11648/j.cnn.20180202.11
T2  - Clinical Neurology and Neuroscience
JF  - Clinical Neurology and Neuroscience
JO  - Clinical Neurology and Neuroscience
SP  - 23
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PB  - Science Publishing Group
SN  - 2578-8930
UR  - https://doi.org/10.11648/j.cnn.20180202.11
AB  - Dopa-responsive dystonia, also known as hereditary progressive dystonia with diurnal variation, is a genetic disease characterized by childhood or adolescent onset of dystonia and sometimes associated with parkinsonian features. This is a case report of an 18 year old Nigerian University undergraduate with features of difficulty in speaking, stiffness of the body, gait difficulties, coarse tremors and toe-walking. There was a very marked improvement of symptoms and signs within 24-48 hours of the commencement of SinemetTM (levodopa/ carbidopa) 125mg/12.5mg daily. The patient was discharged after 5 days with normal gait.
VL  - 2
IS  - 2
ER  -

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Author Information

Olusegun Adesola Busari

Department of Medicine, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria
Paul Olowoyo

Department of Medicine, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria
Segun Oladele Adeniyi

Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria
Bidemi Olayemi Onipede

Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria
Olisa Joseph

Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria
Solomon Ogunniran

Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria

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Plain Text BibTeX RIS

APA Style

Olusegun Adesola Busari, Paul Olowoyo, Segun Oladele Adeniyi, Bidemi Olayemi Onipede, Olisa Joseph, et al. (2018). Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian. Clinical Neurology and Neuroscience, 2(2), 23-26. https://doi.org/10.11648/j.cnn.20180202.11

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ACS Style

Olusegun Adesola Busari; Paul Olowoyo; Segun Oladele Adeniyi; Bidemi Olayemi Onipede; Olisa Joseph, et al. Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian. Clin. Neurol. Neurosci. 2018, 2(2), 23-26. doi: 10.11648/j.cnn.20180202.11

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AMA Style

Olusegun Adesola Busari, Paul Olowoyo, Segun Oladele Adeniyi, Bidemi Olayemi Onipede, Olisa Joseph, et al. Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian. Clin Neurol Neurosci. 2018;2(2):23-26. doi: 10.11648/j.cnn.20180202.11

Copy | Download

@article{10.11648/j.cnn.20180202.11,
  author = {Olusegun Adesola Busari and Paul Olowoyo and Segun Oladele Adeniyi and Bidemi Olayemi Onipede and Olisa Joseph and Solomon Ogunniran},
  title = {Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian},
  journal = {Clinical Neurology and Neuroscience},
  volume = {2},
  number = {2},
  pages = {23-26},
  doi = {10.11648/j.cnn.20180202.11},
  url = {https://doi.org/10.11648/j.cnn.20180202.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20180202.11},
  abstract = {Dopa-responsive dystonia, also known as hereditary progressive dystonia with diurnal variation, is a genetic disease characterized by childhood or adolescent onset of dystonia and sometimes associated with parkinsonian features. This is a case report of an 18 year old Nigerian University undergraduate with features of difficulty in speaking, stiffness of the body, gait difficulties, coarse tremors and toe-walking. There was a very marked improvement of symptoms and signs within 24-48 hours of the commencement of SinemetTM (levodopa/ carbidopa) 125mg/12.5mg daily. The patient was discharged after 5 days with normal gait.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian
AU  - Olusegun Adesola Busari
AU  - Paul Olowoyo
AU  - Segun Oladele Adeniyi
AU  - Bidemi Olayemi Onipede
AU  - Olisa Joseph
AU  - Solomon Ogunniran
Y1  - 2018/07/04
PY  - 2018
N1  - https://doi.org/10.11648/j.cnn.20180202.11
DO  - 10.11648/j.cnn.20180202.11
T2  - Clinical Neurology and Neuroscience
JF  - Clinical Neurology and Neuroscience
JO  - Clinical Neurology and Neuroscience
SP  - 23
EP  - 26
PB  - Science Publishing Group
SN  - 2578-8930
UR  - https://doi.org/10.11648/j.cnn.20180202.11
AB  - Dopa-responsive dystonia, also known as hereditary progressive dystonia with diurnal variation, is a genetic disease characterized by childhood or adolescent onset of dystonia and sometimes associated with parkinsonian features. This is a case report of an 18 year old Nigerian University undergraduate with features of difficulty in speaking, stiffness of the body, gait difficulties, coarse tremors and toe-walking. There was a very marked improvement of symptoms and signs within 24-48 hours of the commencement of SinemetTM (levodopa/ carbidopa) 125mg/12.5mg daily. The patient was discharged after 5 days with normal gait.
VL  - 2
IS  - 2
ER  -

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